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Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Mosaic-variegated aneuploidy (MVA) syndrome is a rare childhood disorder characterized by biallelic ...
Using a genome-wide analysis, we demonstrated that PRMT1 is selectively required for progesterone-re...
Transcriptional response to TGF-beta receptor inhibtion with or without VEGFA stimulation SOURCE: Ji...
We report differential gene expression in inflammatory monocyte (IM), tumor-associated macrophage (T...
We have discovered that the alternative splice form of MYH7b is a regulatory non-coding RNA in the h...
CBX4, a component of polycomb repressive complex 1 (PRC1), plays important roles in the maintenance ...
Checkpoint inhibitors like anti-PD1/PD-L1 have demonstrated significant therapeutic efficacy in a su...
Induction of vast transcriptional programs is a central event of innate host responses to viral infe...
mRNA: profiling the neural identity of cancer associated neurons; miRNA: investigating the p53 depen...
HCV infection induce thyroid dysfunction by influencing both immune and non immune thyroid-toxic mec...
Small intestinal group 3 innate lymphoid cells (ILC3) from ILC3-conditional BMAL1 knock out mice or ...
We describe a novel mechanism by which mammals with a low mamary cancer incidence may avert mammary ...
Toll-like receptors (TLRs) have a crucial role in the recognition of pathogens and initiation of imm...
A conserved event of the maternal-to-zygotic transition (MZT) in animal embryos is the elimination o...
mRNA: profiling the neural identity of cancer associated neurons; miRNA: investigating the p53 depen...
In Cichlids, replacement teeth (RT) share a continuous band of epithelium with adjacent taste buds (...
Purpose: The goals of this study are to verify the inhibition of Wnt signaling is suffice to surpres...
RNA-seq analysis of the transcriptome of K562 cells in which PTPN2 or DCAF15 had been disrupted by C...
The rate of RNA Polymerase II (RNAPII) elongation has an important role in the control of Alternativ...
RNA sequencing was performed using shLacZ and shDis3l2 undifferentiated mESCs as well as EB differen...
Mutations in the methyl-DNA-binding repressor protein MeCP2 cause the devastating neurodevelopmental...
To identify HCC-related RNAs, we used four HCC patients fresh tumor tissues and paired adjacent non-...
Aberrant activation of the TAL1 oncogene is associated with up to 60% of T-ALL patients and is invol...
The interactions between tumor cells and the host vasculature and immune cells results in increased ...
IL-17 and IL-17R signaling in the intestinal epithelium regulate the intestinal microbiome. Given th...
Human induced pluripotent stem cells (hiPSCs) were differentiated into alveolar epithelial cells in ...
Purpose: We investigated the transcriptomic change in brown fat of young and old mice (wild type) th...
In this Study, we used RNA-targeting Cas9 (RCas9) to reverse characteristic Myotonic Dystrophy (DM1)...
Airway epithelial cells are crucial for mucosal and adaptive immunity as they produce mucins that tr...
Visceral sensory neurons encode distinct sensations from healthy organs and initiate pain states tha...
To identify genes relevant for cystic fibrosis pathophysiology, we profiled blood samples in CF pati...
The overal goal was to characterize the differential expression of protein-coding genes and lncRNAs ...
EGFR signaling controls skin development and homeostasis in mice and humans and its deficiency cause...
We molecularly characterized thousands of intestinal cells including epithelial, masenchymal and imm...
Chronic but not acute infections cause cachexia, characterized by bodyweight reduction and muscle lo...
Background; Hemispheric asymmetry in neuronal processes is a fundamental feature of the human brain ...
Alternative splicing consists of exons that are selectively either included or excluded from the mat...
RNA-Seq transcriptome comparison of the following cell populations (n=4 independent samples per cell...
This study provides analysis of developing mouse retina organoids derived from induced pluripotent s...
The vomeronasal organ (VNO) of mice contains two main types of vomeronasal sensory neurons (VSNs)- A...
In order to characterize the genetic diversity within the Stratum Griseum Intermediale (SGI), we scr...
Here we study the effect on cell autonomous and systemic Akt isoform deletions in breast cancer SOUR...
Important immune regulatory mechanisms mediated by CD4+ and CD8+ T-cells keep untoward CD4+ T-cell r...
Perturbations in histone modifications alter transcription and promote carcinogenesis. Breast cancer...
We generated a Tcf7l2 F/F mouse and harvested preadipocytes rom these mice, immortalized them, and t...
Investigation of the transcriptional response in Jak1 depleted tumor cells upon NK-derived cytokine ...
Total RNA sequecing for human induced pluripotent derived cerebral organoids from healthy controls a...
Although Tead4 is well-known to be critical for blastocyst development and trophoblast lineage diffe...
We report that knocking down the Mitochondrial Pruvate Carrier 1 (MPC1) in the hearts of adult mice ...
We report a subset of genes upregulated by TGFBeta after three hours of treatment SOURCE: Asha Nair ...
The squamouscolumnar junction (SCJ) is a boundary consisting of precisely positioned transitional ep...
ESRP1 is an epithelial-specific splicing factor. It mainly regulates expressions of genes related to...
Col1a1GFP+ cells from the spinal cords of healthy mice or mice in the early stages of EAE symptoms w...
Hormone dependent activation of enhancers includes histone hyperacetylation and mediator recruitment...
Although the olfactory mucosa possesses long-lived horizontal basal stem cells (HBCs) and remarkable...
Toidentifythegenesassociatedwith the knockdownof ELL2.PC-3 mRNAprofilesofcellstreatedwithRNAinterfer...
To fine map the continuum of molecular changes that occur as B cells differentiate to antibody secre...
During B cell development, recombination of immunoglobulin loci is tightly coordinated with the cell...
Fusion proteins involving Nucleoporin 98 (NUP98) are recurrently found in Acute Myeloid Leukemia (AM...
To examine effects of environmental risk factors on pancreatic cancer development, we fed control Pd...
RNAseq from pancreatic cancer cell lines treated with DMSO, taxol, palbociclib or the combination at...
G-quadruplexes (G4) are non-canonical nucleic acid structures that can form at certain DNA or RNA gu...
The main purpose of this study is to investigate the differences between the gene expression profile...
In a model of chronic heart failure, BET bromodomain inhibition delayed cardiac remodeling and fibro...
Regulatory T (Treg) cells maintain self-tolerance in lymphoid tissues, and specialized Treg cells ac...
We report transcriptome analysis of human embryonic stem cells and in vitro differentiated neural s...
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular path...
Multicellular organisms evolved via repeated functional divergence of transcriptionally related sist...
To determine the effect of darunavir upon HIV-induced gene regulation in renal epithelial cells, imm...
We conduct transcriptome comparison of control and Mtss1-overexpressed Py8119 cells to gain genomic ...
Here we show that, when compared to control mice, muscle specific HuR knockout (muHuR-KO) animals ha...
Background. Accumulation of extracellular matrix in the myocardium attenuates cardiac contractile fu...
Purpose: Hepatic stellate cells (HSCs) plays an important role in liver fibrosis. Recombinant human ...
Investigation of the tumor transcriptional response upon NK cell attack using 3 RNA sequencing SOURC...
We overexpressed Prdx1 in HeLa cells to study Prdx1-regulated genes using RNA-seq technology, follow...
Purpose: To determine the effects of sodium arsenite in male mice on adaptive thermogenesis.; Method...
We developed a nanobiologic platform that is designed to induce trained immunity. Through extensivei...
We report single cell RNA-seq data from patient-derived xenografts that were dissociated, FACS sorte...
Objectives: Understanding the molecular mechanisms underlying cartilage degeneration and regeneratio...
We report changes in gene expression from iPSC to iPSC-derived brain microvascular endothelial cells...
The activity and survival of retinal photoreceptors depend on support functions performed by the ret...
Several recent studies have suggested that genes that are longer than 100 kb are more likely to be m...
Overexpression of activin A by keratinocytes accelerates excisional wound healing in mice. Activin-p...
Ifitm3 (interferon-inducible transmembrane protein 3) was previously identified as an endosomal anti...
Alzheimers disease (AD) is a common form of dementia characterized by amyloid plaque deposition, TAU...
Background: Mesenchymal stem cells (MSCs) can be acquired from medical waste. MSCs are easily expand...
We report that TTP exhibits context-dependent target destabilisation and that such context-defined m...
We performed RNA-sequencing of ZBTB38-sufficient and -deficient germinal center B cells. Very few ge...
RNA-seq was performed to compare the transcriptional programmes of palbociclib-resistant A375 and C...
The goal of this study was to compare global RNA expression data obtained from: i) duodenal organoid...
Sustained ER stress is tightly associated with hyperglycemia and type 2 diabetes.However, the molecu...
Temporal dynamics of gene expression are informative of changes associated with disease development ...
Alternative splicing (AS) creates proteomic diversity from a limited size genome by generating numer...
To examine differences in the transcriptome of resident memory CD8 T cells in the lung, influenza nu...
Fibrosis of the kidney is the final common pathway leading to end stage renal failure. By analyzing ...
Transcriptome analysis of lineage marked AR-deleted and wild type luminal prostate epithelial cells ...
Small RNAs derived from mature tRNAs, referred to as tRNA fragments or tRFs, are an emerging class o...
The development of the mammalian inner ears is a highly dynamic process that is dependent on the int...
The Human Silencing Hub (HUSH) complex is necessary for epigenetic repression of LINE-1 elements. We...
Lipid-rich myelin forms insulating axon-wrapping multilayers essential for neural function, but how ...