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Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Our previous studies showed that Lgr6+ cells are a subpopulation of Lgr5+ progenitor cells and that ...
Mice were challneged with Mycobacterium abscessuscell wall particles intra- tracheally or saline. Lu...
We report whole genome data for in vitro mouse monolayers with different culture time/transepithelia...
Ectopic expression of defined transcription factors can force direct cell fate conversion from one l...
Cholestasis is a multifactorial disorder that compromises liver function. We wanted to examine Phase...
Transcriptional profiling of human intestinal organoids following human norovirus infection. SOURCE:...
Analysis of HEK293 cells lines expressing mutant ribosomal protein RPS2 (human A226Y). RPS2 A226Y m...
Identification of novel differentially expressed genes in human M1 and M2 macrophages using RNA-Seq ...
Recent advances in stem cell technology have led to the development of three-dimensional (3D) cultur...
B-1 and B-2 lymphocytes are derived from distinct developmental pathways, and represent layered arms...
In order to examine the role of a-DR3 on group 3 innate lymphoid cells, we treated Rag1-/-Rorcgfp/+...
Lin28A and its paralog Lin28B are RNA binding proteins that regulate gene expression by inhibition o...
Induction of trained immunity by human Bacille-Calmette-Gurin (BCG) vaccination is implicated in the...
Lats1/2 kinases are the core Hippo pathway kinases. In this study, we use RNAseq to analyze the gene...
Transcriptome analysis of hematopoietic cells under homeostasis and regeneration at single cell reso...
We provide here the alterations in gene expression profiles of HepaRG cells, a validated model for c...
Purpose:Sirtuin 6 (Sirt6) is a highly conserved ADP-ribosylase and NAD+ dependent deacylase, involve...
The presence of disseminated tumour cells (DTCs) in bone marrow predicts poorer metastasis-free surv...
We used RNA-seq technology to characterise the extent of transcriptional response to transverse aort...
To evaluate the transcriptome and splicing repertoire of bulk CD34+ sorted bone marrow progenitors w...
To confirme the function of methylated micro RNAs (miR-17 and let-7a), we transfected methylated or ...
We report the RNAseq data obtained from 50.000-100.000 CD31-/CD45- pneumocytes isolated by FACS from...
We analyzed the transcriptome (RNA-seq) of glomeruli in a mouse model of light chain deposition dise...
circRNAs profile were examined upon TGF-beta treatment in A549 cells SOURCE: yu xiang (yu.xiang@uth....
This study aims to determine the effects of proinsulin misfolding/ER stress on -cell dynamics and fu...
Background: Nicotine and alcohol are often co-abused. Adolescence is a vulnerable period for the ini...
Homologous recombination is required for proper segregation of homologous chromosomes during meiosis...
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of Y95 phosphory...
In this study we show that TGF-activated kinase 1 (TAK1), is crucial for ensuring EC survival on TNF...
Using genetically modifed mice to express fluorescent reporter in proglucagon expressing cells (GluV...
Endothelial TGF signaling is one of the primary drivers of atherosclerosis-associated vascular infla...
Gene expression of memory CD4+ and CD8+ T cells determined by RNAseq 30 days after LCMV Armstrong in...
The transcriptomes of mouse testes isolated from 8 weeks old male littermates carrying germline Rlim...
Transcriptomic changes in U2OS cells upon depletion of the RNA-binding protein ZNF598 were analyzed ...
Gut-draining mesenteric lymph nodes (mLNs) play a key role in peripheral tolerance towards food and ...
Using a mouse model overexpressing human SNCA and profiling the striatal transcriptome, we assessed ...
The inability to derive fully functional cell types, such as hepatocytes, from stem cells may emanat...
IL33 is an alarmin protein that is known to be released by epithelial cells as a response to damage....
The small RNA payload of mammalian sperm undergoes dramatic remodeling during development, as severa...
Purpose:Next Generation Sequencing applying for compare the iNKT cells at stage2 and stage3 distict ...
Dedifferentiated Fat Cells (DAs) and Adipose-derived stem cells (ADSCs) are two main stem cells deri...
Microglia have emerged as crucial players in the maintenance of mechanical hypersensitivity in model...
To identify sex-based differences in gene pathways affected by endgoenous genomic instaiblity result...
To determine which genes are affected by methylated Pontin, we performed RNA-sequencing (RNA-seq) in...
Many lung diseases result from a failure of efficient regeneration of damaged alveolar epithelial ce...
We report the effect of splicing upon O-GlcNAc perturbation with OGT inhibitor or OGA inhibitor. We ...
IL-10 is a prototypical anti-inflammatory cytokine, which is fundamental to the maintenance of immun...
We identified 4,356 genes with expression differences associated with a high-fat diet, with 184 gene...
We transfected PC3 cells with 100nM of a scrambled antisense oligonucleotide (AON) and an AON direct...
Cancer evolution is fueled by genetic and epigenetic diversity, and intra-tumoral heterogeneity in D...
Pancreatic ductal adenocarcinoma (PDAC) still carries a dismal prognosis with overall five-year surv...
Plasmacytoid dendritic cells (pDCs) are an immune subset devoted to the production of high amounts o...
By characterizing the meningeal compartment of naive mice, here we explored a unique population of t...
Adaptation of liver to the postprandial state requires coordinate regulation of protein synthesis an...
RNAseq were performed to analyze the transcriptomic differences between Trim27-overexpressing MP and...
Mouse embryonic pancreata at 14.5 dpc were cultured for two day in air to liquide interface cultures...
Plasmacytoid dendritic cells (pDCs) are an immune subset devoted to the production of high amounts o...
Cg.5XFAD females (MMRRC Stock No #34848-JAX) were bred to males from BXD strains. The resulting F1 p...
By taking advantage of the highly immunogenic live-attenuated yellow fever virus vaccine YFV-17D, we...
The gut microbiome is a dynamic, malleable microbial community that can provoke phenotypic changes i...
Background & Aims; Hepatocytes differentiated from human embryonic stem cells (hESCs) have the poten...
We sequenced seven neuroblastoma cell lines, including the parental NLF neuroblastoma cell line and ...
Pancreatic ductal adenocarcinoma (PDAC) is characterized by the presence of abundant desmoplatic str...
The mammalian inactive X-chromosome (Xi) is structurally distinct from all other chromosomes and ser...
Nociceptors are neurons responsible for the detection of pain producing stimuli. Persistent changes ...
Loss-of-function variants in CCM3/PDCD10 predispose to cerebral cavernous malformations (CCMs) that ...
The Nucleosome Remodeling and Deacetylase (NuRD) complex plays an important role in gene expression ...
The pregnant decidua is infiltrated by many immune cells which are thought to originate in the bone ...
Midbrain dopamine neurons project to numerous targets throughout the brain to modulate various behav...
We examined the transciptomic changes to primary adipocytes resulting from exposure to IFNb and/or L...
Using single cell RNA sequencing (scRNA-seq) on cerebrospinal fluid (CSF) and blood from adults with...
We provide a comprehensive single cell mRNA-seq analyses of mouse bone marrow progenitors revealing ...
The ATG16L1-deficient intestinal organoids display increased IFN-I signature. SOURCE: Yu Matsuzawa (...
We performed RNASeq and confocal imaging analysis to characterize the gene expression changes in the...
Generation of T cells from pluripotent stem cells (PSC) has the potential to transform adoptive immu...
By performing RNA sequencing (RNA-seq) analysis on the peritoneal macrophages that derived from ALKB...
To examine whether ALYREF can facilitate the 3'processing of RD histone mRNA,we isolated and sequenc...
Sickle cell disease (SCD) results from a point mutation in the -globin gene forming hemoglobin S (Hb...
Estrogen receptor positive (ER+) breast cancers that develop resistance to therapies that target the...
Cellular and transcriptional experiments demonstrate that deletion of Ptpn2 enhances CD8+ T cell res...
Purpose: We performed a time-course single-cell RNA-seq of the somatic cells of the XX mouse gonads ...
Xrn1 is a cytoplasmic 5-3 exoribonuclease responsible for degradation of multiple types of RNA. Data...
Lung cancer is closely associated with chronic inflammation, but the mechanism underlying such infla...
Cancer-augmented lactogenesis has been described by the Warburg effect, and is associated with sever...
Diffuse intrinsic pontine gliomas (DIPG) are devastating pediatric brain tumors for which there is n...
Macrophages derived from the wt and 1h mice were treated with the increasing concentrations of the T...
RNA-sequencing of mRNA isolated from in vitro decidualizaing human endometrial stromal cells with or...
RNA sequencing demonstrates molecular profiles common to primary tumor, PDX and organoid models SOUR...
Gene expression profile of T cell after TCR stimulation with or without PD-1 engagement was measured...
Oligodendrocyte precursor cells (OPCs) constitute the main proliferative cells in the adult brain, a...
ARID1A restrains the formation of PanIN, pancreas ductal adenocarcinoma, and intraductal mucinous ne...
Nicotine dependence is responsible for perpetuating the adverse health effects due to tobacco use, t...
The extraordinarily thin alveolar type 1 (AT1) cell constitutes nearly the entire gas exchange surfa...
We have discovered that loss of wild-type p53 correlates with elevated expression of mevalonate path...
High-risk B-cell acute lymphoblastic leukemia (B-ALL) remains a therapeutic challenge despite advanc...
Purpose: Cortical thymic epithelial cells (cTECs) contain a unique type of proteasomes, thymoproteas...
We report significant differences in muscle gene expression during postnatal development (4-8 weeks)...
Dysfunction of blood vessels leads to severe vasculature pathogenesis. Previous studies have demonst...
Pathological cardiac hypertrophy is a major risk factor for the development of heart failure and sud...
Enteroendocrine cells (EECs) alter hormone expression while migrating along the crypt-villus axis. W...