PLX265578

GSE100546: Defining the responses governing disease tolerance during Citrobacter rodentium infection of mice by deep RNA sequencing

• Organsim mouse
• Type RNASEQ
• Target gene
• Project ARCHS4

We performed deep RNA sequencing and systematically analyzed the global gene expression profiles of C. rodentium-infected colon tissues from both susceptible and resistant congenic mice strains to determine the common transcriptomic responses to infection and the Rspo2-mediated dysregulated pathway signatures associated with the loss of disease tolerance. SOURCE: Samantha Gruenheid (samantha.gruenheid@mcgill.ca) - McGill University