PLX257421

GSE100687: RNA-Seq analysis of breast cancer cells after shikonin treatment

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We performed RNA-seq analysis using differnt breast cancer cell lines (MCF-7, SK-BR-3 and MDA-MB-231) after shikonin treatment. We reported that shikonin enhances the expression of DUSP-1 and DUSP-2. Shikonin induces apoptosis and decreases the phosphorylation of JNK1/2 through activationg DUSP-1 and DUSP2. SOURCE: CHIA-YANG LI (chiayangli@gmail.com) - Kaohsiung Medical University

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