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Learn MoreWe mapped the enhancer and long non-coding transcriptional landscape during mesendoderm specification. Mesendodermal progenitors were sorted from differentiating ESCs according to Eomes expression. Enhancer usage was coordinated with mesendoderm-specific expression of key lineage-determining transcription factors. We demonstrated that many of these enhancers are associated with the expression of lncRNAs. SOURCE: Frederic Burdet (frederic.burdet@isb-sib.ch) - Swiss Institute of Bioinformatics
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