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Learn MoreTGF-b treatment leads to the transcriptional regulation of many genes. However, the proportion of those that are dependent on SMAD1/5 is unknown. Here, we compared the transcriptional profile after TGF-b treatment in a parental clone and one in which SMAD1/5 had been deleted by CRISPR/Cas9 to identify SMAD1/5 dependent genes. SOURCE: Caroline,S,Hill (caroline.hill@crick.ac.uk) - Francis Crick Institute
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