PLX306032

GSE106510: T helper cells modulate intestinal stem cell renewal and differentiation

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Using single-cell RNA-seq of intestinal epithelial cells we identify surprising expression of MHC class II, which participates in a novel interaction between gut-resident CD4+ T cells and epithelial stem cells, governing the balance between stem cell differentiation and renewal. SOURCE: Adam HaberRegev Lab Broad Institute

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