PLX102405

GSE108084: Early response of human ovarian and fallopian tube surface epithelial cells to norepinephrine

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

The purpose of this study is to understand the effects of adrenergic signaling on the transcriptome of cell line models postulated to be the cells of origin of epithelial ovarian cancers using RNA-Seq. Here we explored the effects of the stress-related hormone, norepinephrine, on normal human ovarian and fallopian tube surface epithelial cellss. We investigated the early transcriptional response to norepinephrine in normal immortalized ovarian surface epithelial cells and fallopian tube secretory cells. RNA-Seq data of treated and untreated cells were analyzed to identify genes with differential expression. SOURCE: Chia-Ho Cheng (chia-ho.cheng@moffitt.org) - Cancer Informatics Core Moffitt Cancer Center

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