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PLX048495
GSE116241: Identification of atheroprone shear stress responsive regulatory elements in endothelial cells
- Organsim human
- Type RNASEQ
- Target gene
- Project ARCHS4
While variations in gene transcription networks in models of atherosclerosis have been reported, the underlying changes in the chromatin landscape induced by pro-atherogenic stimuli remain elusive. In the present study, we report changes in chromatin regulatory elements that mediate transcriptional control upon the application of oscillatory shear stress of 3 dyn/cm2 in primary cultured human umbilical vein endothelial cells (HUVECs) at 6 h time point of oscillatory shear stress stimulation compared to static condition. SOURCE: Olga Bondareva WWU
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