PLX250512

GSE120858: MYCN knock-down leads to DNA-repair deficiency in human neuroblastoma (RNA-Seq)

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We knock down MYCN in human neuroblastoma cell line by RNAi. MYCN knock-down caused global epigenome change, including nucleosome gain on key DNA-repair genes and promoter H3K9ac down regulation. SOURCE: Weisheng Zheng (wisense@2008.sina.com) - Jiang Lab Tongji University

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