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Learn MoreWe examined the transcriptional changes modulated by estrogen receptor beta (ER) by performing global transcriptome analysis. U87 cells were transduced with lentiviral particles carrying either empty vector or ER-FLAG expression vector and the RNA was isolated and utilized for RNA-seq analysis. Our results demonstrated that ER modulated genes were related to homologous recombination, DNA damage response, ATM signaling and cell cycle pathways. SOURCE: YI ZOU (zou@uthscsa.edu) - UTHSA-GCCRI
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