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PLX184680
GSE128696: Gene expression comparison of resting human peripheral-blood NK cells and activated counterparts
- Organsim human
- Type RNASEQ
- Target gene
- Project ARCHS4
Resting NK cells are notoriously difficult to transduce, especially using the VSVG lentivirus pseudotype. When NK cells are expanded and activated using the NKAES system, there is a modest improvement of transduction rates compared to their resting NK counterparts. Still, the transduction efficiency remains poor for robust development of NK cell-based cancer immunotherapy. We envisaged to have a genome-wide expression profile of resting and activated NK (NKAES) cells in order to improve currrent transduction protocols . SOURCE: Panojot Bifsha (panojot.bifsha@gmail.com) - CHU Sainte-Justine
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