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Learn MoreDolastatin 15 is a known tubulin binding agent and shows remarkable differential cytotoxicity against a panel of colorectal HCT116 isogenic cells. The compound causes anti-vascularization effect in human endothelial cells (HUVEC) in a dose dependent manner. Antiangiogenic effect was further validated in a zebrafish genetic model with activated HIF SOURCE: Tongjun Gu (tgu@ufl.edu) - The University of Florida
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