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Learn MoreOur study shows that after extended stimulation of human CD4+CD25+CD127- Tregs in vitro, a stable cell subset that downregulates CD27 and upregulates CD70 develops. Expanded CD27+CD70- Tregs display a gene profile which closely relates to the previously described Treg gene signature, whereas CD27-CD70+ Tregs express some genes associated with Treg gene signature and some genes overexpressed in conventional T cells. SOURCE: Rebeca,Casilda,Arroyo Hornero (rebeca.arroyo@outlook.com) - TRIG University of Oxford
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