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Learn MoreBudesonide alter cell function through gene expression changes that occur via activation of ubiquitously expressed intracellular glucocorticoid receptors. However, a number of recent studies suggest that budesonide also activate rapid alterations in various signaling processes that appear to be non-genomic in nature, and likely dependent on Gs. Here, we investigate the Gs dependent non-genomic transcriptional activity due to 24 hours of budesonide treatment. SOURCE: Moom,R,Roosan (roosan@chapman.edu) - Chapman University School of Pharmacy
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