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Learn MoreStudy was conducted to understand the effect of the cancer associated H2BG53D mutation in PDAC. Using CRISPR/Cas9 Knock-in cell lines expressing FLAG-tagged WT and G53D mutant H2B, we conducted gene expression profilling experiments and studied the effect of the H2BG53D mutation on transcription and PDAC development. SOURCE: Ming,Kui,Chan (ming.chan@cityu.edu.hk) - City University of Hong Kong
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