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Learn MoreSingle cell RNA-seq analysis of CD11b+ cells sorted from murine syngeneic gliomas, indicating distinct activity ofmicroglia, infiltrating monocytes/macrophages and CNS border associated macrophages. It demonstrates a molecular heterogeneity in the innate immune response in gliomas. Differently expressed genes were identified in activated microglia from glioma-bearing mice of different sex, and profound overexpression of the MHCII genes was observed in male microglial cells. SOURCE: Jakub Mieczkowski (jmieczkowski@jmieczkowski.pl) - Nencki Institute
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