PLX207812

GSE138704: RNA-binding protein IGF2BP1 maintains leukemia stem cell properties by regulating HOXB4, MYB, and ALDH1A1.

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

IGF2BP1 promotes leukemia stem cell phenotype by regulating HOXB4, MYB and ALDH1A1. Inhibition of IGF2BP1 reduces leukemia tumorigenicity, and enhances leukemia cell death and differentiation. SOURCE: Irina Elcheva (irina.elcheva@gmail.com) - C7848 PennState College of Medicine

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