PLX273382

GSE138774: RNA-seq analysis using glomeruli isolated from control and podocyte-specific bPIX deficient mice

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We found that podocyte-specific bPIX deficient (KO) mice developed progressive proteinuria starting at ~8 weeks of age, and glomerulosclerosis and podocyte loss by 13 weeks of age. To investigate the mechanism of podocyte loss induced by bPIX deficiency, we analyzed mRNA expression by RNA-sequence using isolated glomeruli from control (CTRL) and KO mice. SOURCE: Tomoko Takano (tomoko.takano@mcgill.ca) - Division of Experimental Medicine McGill University Health Centre (MUHC)

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