PLX277771

GSE138909: Transcriptional profiling of nave and in vitro activated B cells from WT and DOT1L KO mice

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We studied the role of the histone methyltransferase DOT1L in B cell development and differentiation. Here we generated RNA-seq data naive B cells from (WT) MB1+/-;Dot1L+/+ and Dot1L KO (MB1+/-;Dot1Lfl/fl) mice. This data was to define tissue specific expression signatures and it was compared with H3K79me2 ChIP-seq data from the same subsets. SOURCE: Fred van Leeuwen (fred.v.leeuwen@nki.nl) - Netherlands Cancer Institute

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