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Learn MoreThe differentiation of nave CD4+ T cells into T helper (Th) subsets is key for a functional immune response and has to be tightly controlled by transcriptional and epigenetic processes. However, the function of cofactors that connect gene-specific transcription factors with repressive chromatin-modifying enzymes in Th cells is yet unknown. Here we determined transcriptional changes in Th1 cells upon deletion of the cofactor NCOR1. SOURCE: Wilfried Ellmeier (wilfried.ellmeier@meduniwien.ac.at) - Medical University of Vienna
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