PLX173077

GSE139439: Next Generation Sequencing Facilitates Quantitative Analysis of Wild Type and cd36-/- murine peritoneal macrophage Transcriptomes

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Oxidized LDL induce macrophages to turn into foam cells in a CD36 dependent manner. The Goal of this study is to compare transcriptome profile by RNA-seq among WT/CD36 knockout macrophages treated with or without oxLDL. We detected re-organization of lipid metabolisms as well as immune activation by oxLDL. SOURCE: Yiliang Chen Blood Research Institute, Versiti

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