PLX207999

GSE141525: The role of histone H3K27 acetylation for enhancer activity in embryonic stem cells

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

By substituting lysine 27 in histone variant H3.3 to arginine in mouse embryonic stem cells, we measured H3K27ac/H3K4me1/H3K4me3 and other acetylation modifications in H3.3K27R mutant cells, together with RNA-seq and ATAC-seq to measure the transcription activity and chromatin accessibility, respectively. SOURCE: Zhuqiang Zhang (zhangzhuqiang@ibp.ac.cn) - Institute of Biophysics, CAS

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