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Learn MoreThe eRNAs are non coding transcripts involved in the control of gene expression. To verify the biological effects of IRENE-SS and -div (Intergenic Regulatory Element Nkx2-5 Enhancer -same strand and -divergent) knockdown, we analyzed the differentially gene expression profile of cells treated with either of the two specific gapmers versus cardiomyocytes transfected with a scrambled sequence control. We also determined whether IRENE-SS or -div silencing modified the expression of NKX2-5 target genes. SOURCE: Simone Serio (simone.serio@humanitasresearch.it) - Humanitas Research Hospital
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