PLX307487

GSE144767: Identification of miR-29a-mediated target transcriptome in human pancreatic stellate cells (hPSCs) using RNAseq approach

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

In this study, we aim to understand the role of miR-29a in in regulating hPSCs. Identification of the differentially expressed direct and indirect miR-29a targets and the associated pathways from the RNASeq data delineates gene interactions and networks essential for activated PSCs in pancreatic ductal adenocarcinoma (PDAC) in regulating desmoplasia and tumor-stomal crosstalk, which are crucial mechanisms for PDAC progression. SOURCE: Janaiah Kota (jkota@iu.edu) - Indiana University School of Medicine

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