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Learn MoreHere we show that the histone methyltransferase MLL4 (Kmt2d) is required for stem cell activity and an aggressive form of acute myeloid leukemia (AML) harboring the MLL-AF9 oncogene. MLL4 exerts its function by regulating transcriptional programs associated with the anti-oxidant response. SOURCE: Robert,Babak,Faryabi (faryabib@mail.nih.gov) - Laboratory of Genome Integrity National Institutes of Health
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