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PLX186708
GSE63813: RNA sequencing of allelic series of miR-17~92 mutant embryos.
- Organsim mouse
- Type RNASEQ
- Target gene
- Project ARCHS4
We report the generation of an allelic series of miR-17~92 mutant mice, each carrying the targeted deletion of specific miRNA families encoded by the cluster. We integrate the phenotypic characterization of these strains with RNA-seq analysis showing the consequences of selective miRNA inactivation on gene expression in the developing embryo. SOURCE: Andrea Ventura (venturaa@mskcc.org) - Ventura Memorial Sloan Kettering Cancer Center
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