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PLX044794
GSE71541: Expression profile of wild type (WT) vs miR-155-/- in FLT3-ITD+ AML (MV4-11) cell lines
- Organsim human
- Type RNASEQ
- Target gene
- Project ARCHS4
The expression profile in miR-155-/- FLT3-ITD+ AML is unknown. Using empty vector (EV) or two distinct miR-155 (S3 or S10) lentiviral CRISPR-Cas9 infected FLT3-ITD+ AML cell lines (MV4-11 cells), we performed next generation RNA sequencing to determine the expression profile in these cells dependent on miR-155. We found a number of pathways dysregulated, including STAT5 activation. SOURCE: Ryan O'Connell (ryan.oconnell@path.utah.edu) - EEJMRB 4280 University of Utah
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