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PLX041965
GSE76303: Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl
- Organsim mouse
- Type RNASEQ
- Target gene
- Project ARCHS4
We analysed the effect on the genomic localisation of cohesin (Stag1 and Scc1) and CTCF in CTCF, Smc3 and Wapl single depleted as well as CTCF Wapl double depleted mouse embryonic fibroblasts. Furthermore, we addressed the effect of CTCF and Smc3 depletion on gene expression as measured by RNA-Seq and the transcriptional activity in CTCF and Wapl double depleted cells by GRO-Seq. SOURCE: Roman,R,Stocsits (roman.stocsits@imp.ac.at) - Jan Michael Peters' Lab IMP - Research Institute of Molecular Pathology
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