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Learn MoreIkaros is critical in setting the threshold for T-cell activation and proliferation. Here we used mature CD8+ T cells from mice lacking the zinc finger 4 of Ikaros (Ikaros-Zn4-/-) to study its role in regulating gene expression at early time points after T-cell receptor stimulation. SOURCE: Ameya Champhekar6-535 MRL University of California, Los Angeles
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