PLX073727

GSE83712: ILF2 Regulates RNA Splicing of DNA Damage Response Genes to Confer Poor Prognosis in 1q21-Amplified Multiple Myeloma

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

To understand whether ILF2 is required to ensure the alternative splicing and processing of specific pre-mRNAs in Multiple Myeloma (MM), both in physiological and DNA damage conditions, we performed RNA sequencing (RNA-Seq) analysis of untreated or melphalan-treated ILF2-depleted JJN3 cells. Non-silencing or ILF2 shRNA transduced JJN3 cells were treated with melphalan for 10 hours. SOURCE: Li Zhang (zhangli271828@gmail.com) - The University of Texas MD Anderson Cancer Center

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