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Learn MoreIn order to determine the imprinted transcription factor Zac1 targets, we overexpressed Zac1 in a mouse insulinoma cell line and measured the regulated expressed genes by RNA-seq. We have shown that Zac1 regulates many genes belonging to the Imprinted Gene Network, including genes coding for the extra-cellular matrix. SOURCE: Tristan Bouschet (tristan.bouschet@igf.cnrs.fr) - Functional Genomics of Imprinted Genes Institut de Génomique Fonctionnelle
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