PLX076521

GSE87694: Olfactory receptor accessory proteins play crucial roles in receptor gene choice

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Mice with olfactry accessory protein RTP1 and RTP2 knocked out show severe bias in their olfactory receptor repertoire. Surprisingly, even though RTP1,2(-/-) animals have fewer OSNs, we discovered ~8% of the ORs are expressed in larger numbers than the wild type. SOURCE: Kentaro IKEGAMI (kentaro.ikegami@yohda.net) - Duke University

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