PLX229795

GSE89970: Genome-wide map of HAEC chromatin landscape under resting and TNFa, IL1b, and OxPAPC stimulation, with corresponding transcription factor binding and RNA expression

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

We report the dynamic enhancer landscape of HAEC at baseline and under inflammatory stimulation, and also show the cistromes of ETS, AP-1 as well as key signal dependent transcription factors, with corresponding gene expression. We also describe the inflammatory transcriptional profile caused by inhibition of the ETS factor ERG with siRNA. SOURCE: Casey,E,Romanoski (cromanoski@email.arizona.edu) - University of Arizona

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