PLX060010

GSE90726: RNA sequencing of ESC/iPSC-derived purified PAX6-GFP neural progenitors form control and Phelan-Mcdermid patients

  • Organsim human
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

The goal of this study was to generated and transcriptionally analyze purified populations of Phelan-McDermid and control pluripotent stem cells-derived neural progenitors. This type of analysis allowed us to identify prevoisly unknown transcriptional phenotypic changes in patient neural progenitors which appear to be independent of functional synapses. SOURCE: Reinhard Roessler Whitehead Institute

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