PLX263756

GSE93293: Determination of Lsd1 function in inguinal white adipose tissue (ingWAT) by global transcriptome analysis

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

To investigate the role of Lsd1 in ingWAT we crossed mice harboring conditional Lsd1 alleles (Zhu et al., 2014) with the Adipoq-Cre deleter strain (Eguchi et al., 2011), which results in Cre-mediated loss of Lsd1 selectively in adipocytes. Transciptome analysis of ingWAT obtained from control and knock-out mice revealed 727 genes differentially expressed between Lsd1 knock-out and control mice at 6 weeks of age (p-value<10-2). SOURCE: Delphine Duteil (delphine.duteil@uniklinik-freiburg.de) - AG Schüle ZKF, Uniklinik

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