PLX266519

GSE93325: Proteogenomic characterization of developmental defects in the forebrain resulting from hyperactivated mTOR signaling

  • Organsim mouse
  • Type RNASEQ
  • Target gene
  • Project ARCHS4

Hyperactivated mTOR signaling in the developing brain has been implicated in multiple forms of pathology including tuberous sclerosis complex (TSC).; Here, we present an integrated analysis of transcriptomes and proteomes generated from wild-type and TSC1/Emx1-Cre forebrains.; This led to comprehensive lists of genes and proteins whose expression levels were altered by hyperactivated mTOR signaling. SOURCE: Yukyung Jun (yellow9250@gmail.com) - Ewha Womans University

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