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Learn MoreIn other to assess functional involvement of Klf5 in DR regulation, we made liver-specific Klf5 knockout mice. Ductular reaction upon cholestatic liver injury is severely suppressed in these mice. We conducted RNA-seq analysis on the BECs from control mice and Klf5 LKO mice upon DDC injury to further elucidate the Klf5 functions. SOURCE: Hajime Okada (okaunko@gmail.com) - Cell Growth and Differentiation The Institute of Molecular and Cellular Biosciences
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