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Sequencing-based assays page 30
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GSE59739: RNA-Seq of single cells from the mouse lumbar dorsal root ganglion
In order to establish a consensus catalog of dorsal rott ganglion cell types, we used comprehensive ...
GSE57233: The Prion Protein (PrP) is involved in translation via RNA granule-like mRNPs, a connection which is impaired during neurodegenerative diseases
Cytoplasmic RNA granules have emerged as important elements of posttranscriptional and translational...
GSE103341: RNAseq of FACS Drd1 and Drd2 receptor expressing medium spiny neurons (direct and indirect medium spiny neurons) from 5-6 month BACHD Huntington's disease model mice, compared to WT littermates
mRNAseq for baseline transcriptional profiling of D1 and D2 receptor-expressing medium spiny neurons...
GSE60530: Profile of gene expression in U87-MG xenografts expressing control vector (V0), the ubiquitin ligase KPC1 or the p50 subunit of the NF-kB transcription factor, using RNASeq analysis of transcripts mapped independently to the human and murine genomes
Purpose: We identified KPC1 as the ubiquitin ligase that binds to the p105 precursor of NF-kB, ubiqu...
GSE133796: Slit2 regulates cardiac contractile function and protects hearts against ischemia-reperfusion injury
Background The axon guidance cue Slit2 recently has been found to regulate calcium homeostasis and m...
GSE56066: RNA-seq data from MCF-7 cells (breast cancer model) treated with soy extracts
The MCF-7 were infected with either control adenovirus expressing B-galactosidase (Ad) or adenovirus...
GSE63810: Next Generation Sequencing Comparison of C57BL/6J and BC027072 -/- Eye Transcriptomes
We report the single base pair analysis of the ocular transcriptome from wild type and BC027072 knoc...
GSE108503: Pathway analysis of RNA sequencing of various stages of myodifferentiation identifies conditions favoring type I and type II fibers, and highlights increased efficiency of combined differentiation
RNA-Seq of C2C12 cells differentiated for 0, 2, or 7 days using classic myogenic (DM1), adipogenic (...
GSE61351: RNA-seq Analysis of Mineralizing IDG-SW3 Cultures with Mature Osteocyte Characteristics
We differentiated the murine IDG-SW3 cell line for 28 days until the cells displayed a mature osteoc...
GSE131589: Helios enhances the preferential differentiation of human fetal CD4+ nave T cells into regulatory T cells [RNA-Seq - induced Treg cells].
RNA sequencing was used to compare the transcriptome of in vitro differentiated adult and fetal indu...
GSE57249: Bimodality of gene expression in the blastomeres within 2-cell and 4-cell mouse embryos revealed by single-cell RNA sequencing
It remains an open question when and how the first cell fate decision is made in mammals. Using deep...
GSE61024: RNA-Seq in neurons from E16.5 mouse embryonic cortices from WT and SMCX KO mice
We conducted RNA-Seq (using Direct Ligation of Adapters to first strand cDNA) in neurons from E16.5 ...
GSE133817: Transcriptomic analysis of class I odorant receptor enhancer deletion [eA]
We used RNAseq based transcriptome analysis to compare gene expression changes in the olfactory muco...
GSE62718 (mouse): FOXP1 orchestration of ASD-relevant signaling pathways.
Mutations in the gene encoding the transcription factor forkhead box P1 or FOXP1 occur in patients w...
GSE62149: Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast [RNA-Seq]
Reprogramming of ES cells towards the trophoblast lineage, and specifally into self-renewing TS cell...
GSE59688: CBP/P300 Function in Repression as well as Activation Regulated by Adenovirus Small E1A [RNA-seq]
Oncogenic transformation by adenovirus small e1a depends on simultaneous interactions with P300/CBP ...
GSE57662: Reprogramming of Endothelium Into Hematopoietic Progenitors by Defined Factors and Vascular Induction
Generation of abundant engraftable hematopoietic cells from autologous tissues promises new therapie...
GSE156778: Next Generation Sequencing Facilitates Quantitative Analysis of Control and rhCYGB treated liver transcriptomes [DDC]
Purpose: The goal of this study is to investigate the effect of recombinant human Cytoglobin (rhCYGB...
GSE130160: Patient-derived xenograft models of non-small cell lung cancer for evaluating targeted drug sensitivity and resistance
Background: Patient-derived xenograft (PDX) models are a useful tool in cancer biology research. How...
GSE60890: hnRNPK knock down in Ewing cell line
Ewing sarcoma is a highly aggressive tumor characterized by a translocation between members of the F...
GSE98415: Single cell sequencing of primary dorsal root ganglia from CAST/Ei or C57BL/6 mouse highlights strain differences in cellular populations.
Peripheral nerve regeneration after injury is a complex process involving a large number of transcri...
GSE56276: Imprinted expression is different in visceral yolk sac and cystic embryoid body endoderm
Genomic imprinting is an epigenetic phenomenon resulting in parent-of-origin mono-allelic expression...
GSE58016: Gene silencing triggers Polycomb Repressive Complex 2 recruitment to CpG islands genome-wide [RNA-seq_PcG-KO]
Polycomb group (PcG) proteins are required for normal differentiation and development, and their act...
GSE63086: Heterogeneous nuclear ribonucleoprotein C1/C2 links transcriptional and splicing actions of 1,25-dihydroxyvitamin D
Heterogeneous nuclear ribonucleoprotein C1/C2 (hnRNPC1/C2) functions as an RNA splicing regulator th...
GSE60927: Transcriptional profiling of mouse B cell terminal differentiation defines a signature for antibody-secreting plasma cells
Upon encounter with antigen, mature B cells undergo complex changes in their physiological state and...
GSE115422: Transcriptome profiling of adult mouse bone marrow endothelial cells
We performed RNA sequencing analyses of adult mouse bone marrow endothelial cells. Especially, we in...
GSE61474: Quantitative profiling of long noncoding RNAs with targeted RNA sequencing.
We compared the performance of conventional RNAseq with RNA Capture Sequencing (CaptureSeq) to assem...
GSE133090: Transcriptional profiling of Setd5 mutant cortical tissue
Setd5 inactivation in neural stem cells, zebrafish and mouse leads to a significant H3K36 hypo-methy...
GSE58916: RNA Sequencing Quantitative Analysis of cell lines derived from tumours from two mouse models of human osteosarcoma that recapitulate clinically distinct human osteosarcoma subtypes.
Purpose: Osteosarcoma (OS) is the most common primary bone malignancy. OS consists of several subtyp...
GSE57403: Epigenomic comparison of distinct pluripotent stem cell states reveals a new class of enhancers with roles throughout mammalian development (RNA-seq)
Nave mouse embryonic stem cells (mESCs) and primed epiblast stem cells (mEpiSCs) represent successiv...
GSE63183: Loss of 5-hydroxymethylcytosine is linked to gene body hypermethylation in kidney cancer
Aberrant DNA methylation is common in cancer.; To associate DNA methylation with gene function, we p...
GSE126416: RNA-deep sequencing (RNA-Seq) analysis of dy2J/dy2J (Lama2-CMD mouse model), mdx (DMD mouse model) and Wild-type skeletal muscles
Congenital muscular dystrophy type-1A (Lama2-CMD) and Duchenne Muscular dystrophy (DMD) result from ...
GSE138567: RNA-seq analysis of HBV-infected HepG2-NTCP cells treated by Interferon subtypes
Examination of interferon stimulated genes treated with different kind of interferon subtypes in HBV...
GSE135916: RNA-seq analysis of spleen and liver tissue from wild-type and SXR/PXR knockout mice exposed to PCB-153 or vehicle
Purpose: to investigate transcriptomal differences between wild-type and SXR/PXR knockout mice and t...
GSE126450: Cyclin C Regulated Oxidative Stress Responsive Transcriptome
We report the findings from RNA-seq analysis in oxidatively stressed cells, in addition to findings ...
GSE60853: Transcriptome analysis of two clonally-derived ICC progenitor cell lines [RNA-seq]
Interstitial cells of Cajal (ICC) are electrical pacemakers and mediators of neuromuscular neurotran...
GSE61674: In vitro differentiation of human low threshold mechanoreceptive (LTMR) neurons from embryonic stem cells
Human embryonic stem cells were differentiated into peripheral sensory neurons via the intermediate ...
GSE58107: Characterization of human CDK12 and CDK13 in the regulation of RNA processing
We report the total RNA-seq results after CDK9, CDK12 and CDK13 depletion in human HCT116 cells for ...
GSE124882: FoxP3 and Ezh2 Regulate Tfr cell Suppressive Function and Transcriptional Program [InVitro Ex-Tfr]
InVitro Ex-Tfr RNAseq SOURCE: Peter SageSage Lab Brigham and Women's Hospital
GSE71365: RNA-seq analysis of microglia and infiltrating macrophages in the injured retina
The goal of this study is to identify genes differentially expressed between microglia and infiltrat...
GSE128358: Comparative transcription profiling of mRNA and lncRNA related to C75 effect on pulmonary arterial hypertension
Investigated the expression profile and potential roles of mRNA and long non-coding RNAs (lncRNAs) i...
GSE134608: RNA-seq analysis of the effects of single and compound deletion of Moz (Kat6a) and/or Dlx5 during mouse craniofacial development
The purpose of these data is to investigate the genetic perturbations which underlie the cleft palat...
GSE57910: Genome-wide identification and functional analysis of Apobec-1 mediated C-to-U RNA editing in mouse small intestine and liver
The genome-wide identification, tissue-specificity and functional implications of Apobec-1 mediated ...
GSE100923: Gadd45a modulates aversive learning through post-transcriptional regulation of memory-related mRNAs
Learning is essential for survival, and is controlled by complex molecular mechanisms including regu...
GSE57732: Genomic-scale identification of host genes regulated by EBV during lytic cycle [RNA-Seq]
Infection of resting primary B-lymphocytes by Epstein Barr virus (EBV) generates a population of cel...
GSE58524: Allelic imbalance is a prevalent and tissue-specific feature of the mouse transcriptome
We perform a systematic classification of allelic imbalance in mouse hybrids derived from reciprocal...
GSE89505: Transcriptional profiling of cortex and striatal tissue following chronic dosing of PDE10A inhibitor PF-02545920 in a Q175 homozygous knock-in mouse model of Huntingtons disease
Huntingtons disease (HD) symptoms are driven to a large extent by dysfunction of the basal ganglia c...
GSE57313: MicroRNAs Shape Circadian Hepatic Gene Expression on a Transcriptome-Wide Scale
Introduction: A considerable proportion of mammalian gene expression undergoes circadian oscillation...
GSE108392: The influence of PPFIA1 silencing to gene expression in breast carcinoma cell line and head and neck squamous cell carcinoma cell lines by RNA-sequencing in three dimensional collagen I
PPFIA1 (encodes for liprin-1) locates at the commonly amplified 11q13 region in cancer, but the prec...
GSE57919: Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape
We profiled transcriptome and accessible chromatin landscapes in intestinal epithelial cells (IECs) ...
GSE135625: RNA-seq Analysis of the gene expression regulated by CID755673 in mouse embryonic stem cells
Purpose:The goals of this study is to analyze the candidate genes motified by CID755674 to promote t...
GSE106542: Precursors of human CD4+ cytotoxic T lymphocytes identified by single-cell transcriptome analysis [bulk RNA-seq]
CD4+ cytotoxic T lymphocytes (CD4-CTLs) have been reported to play a protective role in several vira...
GSE62450: MED13cTg heart ventricles and epididymal fat
The heart requires a continuous supply of energy but has little capacity for energy storage and thus...
GSE63180: RNAseq of Individual 4T1 Clonal Populations
The transcriptional profile 23 cell lines derived from single clones of the 4T1 cell lines were asse...
GSE61875: Astrocyte elevated gene-1 (AEG-1) and c-Myc cooperate to promote hepatocarcinogenesis
Double transgenic mice with hepatocyte-specific expression of AEG-1 and c-Myc show aggressive HCC co...
GSE61997: m6A RNA Methylation is Critical for Adequate Exit from Nave Pluripotency and Execution of Mammalian Development (RNA-Seq)
In this study we identify Mettl3, an m6A RNA modification writer, as a critical regulator for termin...
GSE99378: Diverse AR-V7 cistromes in castration-resistant prostate cancer are governed by HoxB13
The constitutively active androgen receptor (AR) splice variant 7 (AR-V7) plays an important role in...
GSE58917: RNA Sequencing Quantitative Analysis and identification of RNA editing sites of Wild Type and ADAR1 editing deficient (ADAR1E861A) murine fetal liver RNA
Purpose: RNA editing by ADAR1 is essential for hematopoietic development. The goals of this study we...
GSE63189: Identification and functional characterization of long noncoding RNAs in breast cancer
In this study, we have integrated RNA-seq data from subcellular fractionated RNA (i.e., cytoplasm, n...
GSE61828: mRNA profiling of hypoxia+SU5416-induced pulmonary hypertension (PH) mouse model treated with an inhibitor of miR-130/301 family
Purpose: Guided by an in silico combination of microRNA (miRNA) target prediction, analysis of trans...
GSE62899: XH lncRNA tend to participate in transcriptional or development regulations as their coding neighbors
We report that head to head long noncoding RNAs contribute to transcription and developmental proces...
GSE62762: Aging-induced type I interferon response at the choroid plexus negatively affects brain function.
We investigated gene expression profile of the Brain's choroid plexus and other organs of young and...
GSE63190: High throughput analysis of three human adipose cell lines PAZ6, SGBS and SW872
We report molecular characterization of human brown and white adipocytes. We showed that PAZ6 and SW...
GSE115449: RNA-seq of HIV bnAb and control individuals PBMC
We sought to determine differences in transcript expression between a cohort of HIV-infected individ...
GSE63782 (mouse): Transcriptional plasticity promotes primary and acquired resistance to BET bromodomain inhibition
Following the discovery of BRD4 as a non-oncogene addiction target in acute myeloid leukemia (AML), ...
GSE97352: Global gene expression profile of dasatinib-resistant RCH-ACV cells
Purpose: Several ALL subtypes have been described depending on their karyotype, cell type, immunophe...
GSE63204: Opposing Roles of STAT1 and STAT3 in IL-21 Function in CD4+ T cells
Interleukin-21 (IL-21) is a type 1 cytokine essential for immune cell differentiation and function. ...
GSE58455: Polyadenylated RNA Sequencing of C57BL/6J Embryonic, Adult and Pressure-Overloaded Hearts
A few reports have implicated specific lncRNAs in cardiac development or failure, but precise detail...
GSE95461: DNA methylation signature defines genes modulated by stromal cell contents of human breast tumors [RNA-seq]
Using genome-wide approaches, we have identified groups of genes modulated by CAF-secreted factors f...
GSE61117: TRIM24 suppresses development of spontaneous hepatic lipid accumulation and hepatocellular carcinoma in mice
Purpose: berrantly high expression of TRIM24 occurs in human cancers, including hepatocellular carci...
GSE61794: PTEN suppresses neoplastic transformation of human neural stem cells by transcriptional repression of Pax7
Our data throw light upon the effect of PTEN deficiency on gene expression, epigenomic modifications...
GSE63194: Histone H3K36M mutation impairs mesenchymal differentiation and drives sarcoma development [RNA-Seq]
The goal of this study is to understand the genome-wide alterations in chromatin landscapy induced b...
GSE61955: Host transcriptome analysis of Aspergillus fumigatus infection in Airway Epithelial Cells
The goal of this study is to determine the transcriptional response of primary normal human bronchia...
GSE108699: On the design of CRISPR-based single cell molecular screens
We demonstrate that vector designs for such screens that rely on cis linkage of guides and distally ...
GSE113312: PolyA-sequencing in IMR-32 cells treated with THZ531 or DMSO
We performed RNA-seq analsysis of polA transcripts in IMR-32 cells treated with THZ531 for 2 and 6h ...
GSE61994: m6A RNA Methylation is Critical for Adequate Exit from Nave Pluripotency and Execution of Mammalian Development (3p-Seq)
In this study we identify Mettl3, an m6A RNA modification writer, as a critical regulator for termin...
GSE61470: Decoding the Transcriptional Program for Blood Development from Single Cell Gene Expression Measurements
Blood and cardiovascular development represent paradigms of embryonic organ formation, with increasi...
GSE126464: WRN knockout effects upon gene expression in SW48 and OVK18
To determine gene expression changes upon CRISPR/Cas9-mediated WRN knockout in SW48 and OVK18. 72 ho...
GSE67379: Chromatin signature identifies monoallelic gene expression across mammalian cell types (RNA-seq)
Monoallelic expression of autosomal genes (MAE) is a widespread epigenetic phenomenon which is poorl...
GSE156789: AP-1 and TGFb-dependent transcriptomic changes in resistant basal cell carcinoma cell line
Tumor heterogeneity and lack of knowledge about resistant cell states remain a significant barrier t...
GSE63608: Effect of REST on cancer invasiveness in MCF-7 and MDA-MB-231 cells using RNA-sequencing (RNA-seq) analysis .
We report a negative correlation of invasiveness with REST expression. In addition, one alternativel...
GSE62718 (human): FOXP1 orchestration of ASD-relevant signaling pathways.
Mutations in the gene encoding the transcription factor forkhead box P1 or FOXP1 occur in patients w...
GSE61008: Investigating gene expression changes in wildtype and TMPRSS2-ERG homozygous mouse prostate tissue
A transgenic TMPRSS2:ERG mouse model was engineered in FVB background and compared to its wildtype ...
GSE62772: Integrative analyses of human reprogramming reveal dynamic nature of induced pluripotency [mRNA-Seq]
Induced pluripotency is a promising avenue for disease modeling and therapy, but the molecular princ...
GSE63836: Synergism between PPAR and glucocorticoid receptor signaling promotes self-renewal of BFU-E erythroid progenitors and increases red cell production [RNA-seq]
Analyses of gene expression by RNA-Seq in mouse E14.5 fetal liver burst-forming unit erythroid (BFU-...
GSE63485: RNA expression analysis upon JMJD1C depletion
The AML1-ETO fusion protein, a transcription factor generated by the t(8;21) translocation in acute ...
GSE58510: Early remodeling of the neocortex upon episodic memory encoding
Understanding the mechanisms by which long-term memories are formed and stored in the brain represen...
GSE61626: RNA-seq analysis of bronchosphere cultures of primary human bronchiolar epithelial cells
Primary human bronchial epithelial cells were transduced with control or hYAP(S127A) lentivirus in s...
GSE133853: Brg1 restrains the pro-inflammatory properties of ILC3s and modulates intestinal immunity [RNA-seq]
In order to search for cell-intrinsic targets for Brg1 in ILC3s, Brg1-deficient and control ILC3s we...
GSE61950: Genome-wide chromatin analysis of Ewing sarcoma (RNA-seq)
We show that EWS-FLI1, an aberrant transcription factor responsible for the pathogenesis of Ewing sa...
GSE63085: Identification of a Molecular Signature for Acute Lyme Disease by Human Transcriptome Profiling
Lyme disease is challenging to diagnose, as clinical manifestations are variable and current tools t...
GSE62171: RNA Polymerase II-associated factor 1 regulates the release and phosphorylation of paused RNA Polymerase II
Release of promoter-proximal paused RNA polymerase II (Pol II) during early elongation is a critical...
GSE63206: Flt3-ITD-induced extrinsic depletion of the normal hematopoietic stem cell reservoir
Gene expression analysis of purified endothelial cells (Ecs), mesenchymal stem cells (MSCs) and mon...
GSE129213: Defining DC response to cognate T cell interaction in the antigen-challenged lymph node [dataset 3]
We designed an experimental set up to probe DC responses to cognate T cell encounter in antigen drai...
GSE61742: Impact of regulatory variation from mRNA to protein
Genetic variants that impact gene regulation are important contributors to human phenotypic variatio...
GSE62571: Comparative Analysis of the hippocampal transcriptome of WT and NONO KO mice
Identifying causes of sporadic intellectual disability remains a considerable medical challenge. He...
GSE128971: Bulk RNA sequencing of CD44Neg, CD44LoKitNeg, CD44LoKitPos and CD44High populations from mouse Aorta-Gonad-Mesonephros (AGM) region
The aim of the experiment was to compare newly defined CD44Neg, CD44LoKitNeg, CD44LoKitPos and CD44H...
GSE59373: HSA21 Single-minded 2 (Sim2) binding sites co-localize with super-enhancers and pioneer transcription factors in pluripotent mouse ES cells [RNA-Seq]
Down syndrome (DS) results from trisomy of chromosome 21 (HSA21). Some DS phenotypes may be directly...
GSE66478: Biochemical fractionation of HEK293 nuclei and RNA-seq of chromatin-associated and soluble-nuclear RNA
Biochemical fractionation of HEK293 nuclei and RNA-seq of chromatin-associated and soluble-nuclear R...
GSE62294: mRNA profiling of Col4a3-Knockout Alport Syndrome mouse model treated with inhibitor of miR-21 at 5.5 weeks of age
Purpose: MicroRNA-21 contributes to the pathogenesis of fibrogenic diseases in multiple organs inclu...