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Sequencing-based assays page 44
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GSE79552: The transcriptome and chromatin accessbility landscape of mammalian germline
We first isolate the PGCs from the Oct4-Gfp knock-in mice, and KIT-positive PGCs from the post-impla...
GSE124880: Comprehensive transcriptional atlas of intestinal immune cells reveals that neuropeptide -CGRP orchestrates ILC2 responses
We combine single-cell RNA sequencing (scRNA-seq) with physiological and genetic perturbations to di...
GSE79602: RNA-seq analysis of testis transcripts from Wt and Trf2-/- mice [RNA-seq]
TRF2 is a paralogue of TATA-box binding protein (TBP) with highest expression in testis. Although Tr...
GSE81940: Epithelial membrane protein 2 (EMP2) deficiency alters placental angiogenesis mimicking features of human intrauterine growth restriction.
Epithelial membrane protein-2 (EMP2) is a tetraspan protein predicted to regulateplacental developme...
GSE77885: The macrophage IRF8-IRF1 regulome is required for protection against infections, and is associated with chronic inflammation (RNA-Seq)
IRF8 and IRF1 are transcriptional regulators that play critical roles in the development and functio...
GSE92274 (mouse): Comparative Transcriptomic Analysis of Hematopoietic System Across Species by Microwell-Seq
Traditional single-cell RNA-seq technologies have shown limitations for large scale experiments. Her...
GSE81106: circRNA-sequencing
circRNA sequencing for 6 samples SOURCE: Ruifeng Liu (luyaoliu@126.com) - Shanxi Provincial Key Labo...
GSE76243: IMP1 re-expression in adult hematopoietic stem cells RNA Sequencing
The onco-fetal RNA-binding protein IMP1 is expressed in fetal liver HSCs, but down-regulated in adul...
GSE157101: TRAP-seq of newly generated olfactory sensory neurons from the open and closed sides of the mouse olfactory epithelium following unilateral naris occlusion
The objectives of this study were to use unilateral naris occlusion (UNO) in order to characterize t...
GSE86828: Age- and Nicotine-Associated Gene Expression Changes in the Hippocampus of APP/PS1 Mice
The etiology of Alzheimer's disease (AD) has been intensively studied. However, little is known abou...
GSE79608: Toxoplasma gondii remodels the cis-regulatory landscape of infected human host cells [RNA-seq]
To study the host transcriptome of human fibroblasts after infection with T. gondii (Type I-RH). SOU...
GSE81144: Gene expression in BRAFV600E thyrocyte
To evaluate SASP in an in vitro model, we analyzed the gene expression profile of BRAFV600E-induced ...
GSE79400: Digitalis-like compounds facilitate redifferentiation of non-medullary thyroid cancer through intracellular Ca2+, cFOS and autophagy dependent pathways
About 20-30% of patients with metastatic non-medullary thyroid cancer (TC) have persistent or recurr...
GSE80550: TRIM28 is an epigenetic barrier to induced pluripotent stem cell reprogramming
Since the discovery of induced pluripotent stem cells there has been intense interest in understandi...
GSE81212: Primary cancer cell culture: mammary-optimized versus conditional-reprogramming [RNA-seq]
Experiments used RNAseq data to compare transcriptomes of primary cells from different genetic backg...
GSE124123: Expansion of bacteriophages during disease worsens intestinal inflammation and colitis
Purified phage was used to prevent tumor growth in a mouse model of bacteria aggravated-colorectal c...
GSE75751: Chromatin decompaction coupled MuERVL endogenous retrovirus activation induces genome-wide DNA demethylation
Mouse embryonic stem cells are heterogeneous and contain rare cells expressing transcripts normally ...
GSE133818: Transcriptomic analysis of class I odorant receptor enhancer deletion [eB]
We used RNAseq based transcriptome analysis to compare gene expression changes in the olfactory muco...
GSE80436: Targeting evasion from Antiangiogenic therapy
Abstract: Therapeutic targeting of tumor angiogenesis with VEGF inhibitors results in demonstrable b...
GSE126457: The Secondary Crest Myofibroblast PDGFRa Controls Elastogenesis Pathway via a Secondary Tier of Signaling Networks During Alveogenesis
To compare the gene expression profiles between normal and Pdgfra deficient secondary crest myofibro...
GSE75688: Single cell RNA sequencing of primary breast cancer.
We performed single cell RNA sequencing (RNA-seq) for 246 primary breast cancer cells and lymph node...
GSE81044: Zfp281 Coordinates Opposite Functions of Tet1 and Tet2 for Alternative Pluripotent States [RNA-Seq]
Pluripotent cell identity comprises a spectrum of cell states including naive and primed states, whi...
GSE142418: Single cell RNA sequencing of cells isolated from the intestinal crypts of mice bearing epithelial cell-specific Ptger4 ablation (Drop-seq)
Crypts isolated from the small intestine of mice bearing epithelial cell-specific ablation of the Pt...
GSE135787: ZAR1 and ZAR2 are Required for Oocyte Meiotic Maturation by Regulating the Maternal Transcriptome and mRNA Translational Activation
Zar1 was the first mammalian maternal-effect gene to be identified. Embryos derived from Zar1-null f...
GSE147364: Transcriptome alterations in the cerebellum of manganese (Mn)-deficient mice
RNAseq was performed using cerebellum tissue of mice with either normal (35 ppm) or Mn-deficient (0 ...
GSE79306: Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levels
Purpose: Exploring mechanisms defining the unique nature of vascular development and differentiation...
GSE125116: RNAseq & Smad and Foxh1 ChIpseq in pluripotent mESC and EBs
Smad2, Smad3, Smad4 and Foxh1 ChIPseq performed in pluripotent mESC and embryonic bodies (EBs). RNAs...
GSE81046: Genetic ancestry and natural selection drive population differences in immune responses to pathogens in humans
Individuals from different populations vary considerably in their susceptibility to immune-related d...
GSE81478: Transcriptome sequencing wide functional analysis of human mesenchymal stem cells
Using RNA-seq, we report here that BM-MSC cells have a distinct transcriptomic signature and express...
GSE80092: Differential expression of Hdc-GFPhi HSPC VS Hdc-GFPlo HSPC hematopoetic stem and progenitor cells from mouse bone marrow
Differential expression of Hdc-GFPhi HSPC VS Hdc-GFPlo HSPC hematopoetic stem and progenitor cells f...
GSE82157: Murine myeloid response to experimental fibrosis
We report the response of murine hepatic macrophages to chronic CCl4 administration in wild-type mic...
GSE84819: Peripherally derived macrophages can engraft the brain independent of irradiation and maintain an identity distinct from microglia
Peripherally derived macrophages infiltrate the brain after bone marrow transplantation and during c...
GSE86791: RNA binding protein CPEB1 remodels host and viral RNA landscapes [RNA-Seq]
In this study, we report that HCMV infection results in widespread alternative splicing (AS), shorte...
GSE82164: Whole transcriptome analysis of diaphragms from FKRPP448L-NSG and NSG mice induced by swimming exercise
Muscle pre-injury is commonly used prior to cell transplantation to enhance engraftment and to furth...
GSE84410: The KDM5 family is required for activation of pro-proliferative cell cycle genes during adipocyte differentiation
Here we have characterized the role of KDM5 family during adipocyte differentiation of 3T3-L1 preadi...
GSE83265: RNA-seq data for bone-marrow-derived macrophages from wildtype and JNK1 knockout mice stimulated with yeast form Candida albicans
mRNA expression profile for BMDMs from wildtype and JNK1 knockout mice stimulated with yeast form Ca...
GSE80449: Effect of estrogens and BMPR2 on mouse kidney gene expression
Blood was drawn and RNA extracted from the ten pooled samples. Transcriptional profile of these samp...
GSE80087: Gene expression profiling of retrovirus PDGFB-induced glioma
We performed gene expression profilings of platelet-derived growth factor subunit B (PDGFB)-induced ...
GSE94965: RNA-seq of IL-4 complex treated tissue resident macrophages vs. monocytic macrophages from LysM Cre+ (WT litermate control) and LysM Cre+ RICTOR KO (myeloid specifically RICTOR deleted) mice
RNA-seq was performed on sorted peritoneal tissue resident macrophages (CD11b+F4/80hiTIM4+) and mono...
GSE79638: Arid3a is required for mammalian placenta development
Previous studies in the mouse indicated that Arid3a plays a critical role in the first cell fate dec...
GSE97728: Induction of Cardiomyocyte Proliferation [pz-822_human]
hiPS derived cardiomycoytes treated with 4 cell cycle genes to induce cardiomyocyte proliferation an...
GSE81066: Genome-wide mRNA expression profiling for Wild Type and Itch-/- colonic mucosa Transcriptomes by RNA sequencing
To test the hypothesis that defects in the termination of inflammatory signaling led to colon inflam...
GSE122929: Sam68 insures proper 3'-end pre-mRNA processing during germ cell differentiation
Male germ cells express the widest repertoire of transcript variants in mammalian tissues. Neverthel...
GSE75589: Core pathway mutations induce de-differentiation of murine astrocytes into glioblastoma stem cells that are sensitive to radiation, but resistant to temozolomide (RNA-seq)
Introduction: Glioma stem cells isolated from human glioblastomas are resistant to radiation and cy...
GSE151921: Multisite methylation profiling of primary human meningioma [RNA-seq]
Multiple stereotatically separate sites from human meningioma were processed for methlyation profili...
GSE84259: TRIM28 controls a gene regulatory network based on endogenous retroviruses in human neural progenitor cells
Endogenous retroviruses (ERVs), which make up 8% of the human genome, have been proposed to particip...
GSE79671: Transcriptional changes induced by bevacizumab combination therapy in responding and non-responding recurrent glioblastoma patients
Purpose: To identify transcriptional changes by RNA-seq in tumor samples, before bevacizumab combina...
GSE131253: Next Generation Sequencing Facilitates Quantitative Analysis of Transcriptomes of Murine Fibroblast Fibroproliferative Response with TGF
AKR-2B cells were grown in an anchorage independent system to assess transcriptional profile of the ...
GSE81975: Gene expression profile of regenerated CD8 T cells and CD8 T cells from LMP2 T-iPSCs
Whereas cytotoxic T lymphocytes (CTLs) represent the most promising therapeutic avenue in cancer imm...
GSE75044: Activation of the pluripotency factor OCT4 in smooth muscle cells is atheroprotective. doi: 10.1038/nm.4109
The multiple claims about reactivation of the embryonic stem cell (ESC) pluripotency factor OCT4 in ...
GSE151950: GDNF drives rapid tubule morphogenesis in novel 3D in vitro model for ADPKD [Pkd2- RNAseq]
We report a profile of 35 genes that are differentially expressed in Pkd2- tubuloids compared to con...
GSE80707: E3 ubiquitin ligase Rfwd2 inactivation effect on embryonic lung development
Transcriptome analysis by RNA-seq of lungs from control and Rfwd2 epithelial-specific conditional kn...
GSE93870: Zika virus infection reprograms global transcription of host cells to allow sustained infection
Zika virus (ZIKV) is an emerging virus causally linked to neurological disorders, including congenit...
GSE146981: Single cell RNAseq reconstruct normal and IPF lung epithelium
Tissue fibrosis is a common pathological outcome of chronic disease that markedly impairs organ func...
GSE84302: RNA sequencing to identify common targets for GSK3
common targets with different GSK3 inhibition approaches SOURCE: Eleonore Beurel (ebeurel@miami.edu)...
GSE137138: Transcriptome upon Mof deletion and Etomoxir treatment in ground-state mouse (m) ESCs
This study describes the transcriptome profiling of: 1) Mof fl/fl mESCs cultured in 2i/LIF medium wi...
GSE75544: Sperm tsRNAs contribute to intergenerational inheritance of an acquired metabolic disorder
Increasing evidences indicate diet-induced metabolic disorder could be paternally inherited, but the...
GSE90573: Direct control of regulatory T cells by keratinocytes
Environmental challenges to epithelial cells trigger gene expression changes that elicit context-app...
GSE77847: Dnmt3a haploinsufficiency transforms Flt3-ITD myeloproliferative disease into a rapid, spontaneous, and fully-penetrant acute myeloid leukemia (Single Cell RNA-Seq)
Cytogenetically normal acute myeloid leukemia (CN-AML) represents nearly 50% of human acute myeloid ...
GSE115100: Transcriptome sequencing of differentially expressed genes of the skin tissue of Ncstn KC mice and normal mice
We constructed keratinocyte-specific Ncstn-knockout mice to investigate the role of NCSTN in the pat...
GSE122796: RNA Sequencing of three pairs of gastric cancer
The prognosis after curative resection of gastric cancer (GC) remains unsatisfactory, and thus, the ...
GSE135792: The effect on the lack of ILCs on the colon of mice exposed to DSS colitis
Anti CD90 was used to deplete ILCs in Rag mice prior to the induction of colitis. After 6 days the m...
GSE111871: Runx/Cbf complexes protect ILC2s from exhaustion during allergic airway inflammation
Group 2 innate lymphoid cells (ILC2s) have tissue-resident competence and contribute to the pathogen...
GSE97789: TGF-beta signaling pathway and male disadvantage in the pathogenesis of the bronchial pulmonary dysplasia
Insufficient activation of the TGF-b signaling pathway leads to abnormalities in embryonic lung deve...
GSE80446: Quantitative Analysis of cortical transcriptomes through Next Generation Sequencing from wild-type mice, wild-type mice treated with IL1b, IL-1R8-/- mice and IL-1R8-/- mice treated with IL1b antagonist Anakinra
Quantitative Analysis of cortical transcriptomes through Next Generation Sequencing (RNA-Seq) from w...
GSE147407: Gene expression analyasis on hippocampal tissue from young Hdac1 cKO and control mice
We performe RNA-sequencing (RNA-seq) and differential gene expression analysis on hippocampal tissue...
GSE84325: Total RNA sequencing of INS-GFP+ cells differentiated from HES3 hESCs treated with DMSO or H1152
To systematically examine the cellular identity of INS+ cells derived after H1152 treatment, INSw/GF...
GSE131304: RNA seq analysis of uterine stromal cells from ovariectomized (OVX) Atg7f/f;Amhr2cre mice
Uterine stromal cells were isolated from OVX Atg7f/f and Atg7d/d mice injected with oil or E2. Each ...
GSE140089: Rehabilitative Impact of Exercise Training on Human Skeletal Muscle Transcriptional Programs in Parkinsons Disease
We performed transcriptional profiling to test the hypotheses that a) type I myofiber grouping sever...
GSE75599: Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure [RNA-seq]
We investigated microRNA expression in motoneurons by performing small RNA sequencing of fluorescenc...
GSE100553: A critical role of histone deacetylases, Mbd3/NuRD and Tet2 in epithelial-mesenchymal cell plasticity and in tumor invasion and metastasis
We have generated and employed reversible and irreversible EMT models of murine breast cancer cells ...
GSE81809 (human): Chemical Enhancement of Direct Cardiac Reprogramming In Vitro and In Vivo
Reprogramming of cardiac fibroblasts into induced cardiomyocyte-like cells (iCMs) in situ represents...
GSE94653: IL-10 signaling remodels adipose chromatin architecture to limit thermogenesis and energy expenditure [RNA-Seq]
Signaling pathways that promote adipose tissue thermogenesis are well characterized, but the physiol...
GSE75667: Definition of the Ras/ERK signal induced chromatin modification at target gene promoters [RNA-seq & ChIP-seq]
Ras plays roles across the spectrum of proliferation, invasion and metastasis. The activity of Ras g...
GSE75775: Neuron-specific changes in gene expression caused by NPC1 deficiency
Background: Niemann-Pick type C is a rare autosomal recessive lysosomal storage disorder presenting ...
GSE139892: Analysis for transcriptome profiling changes in 4'-O-methylpyridoxine (OMP) treated leukemic cells
To validate the transcriptome profiling changes upon pharmacologic inhibition of PDXK, a key enzyme ...
GSE83295: AP-1 transcription factors and the BAF complex mediate signal-dependent enhancer selection
Enhancer elements are regulatory sequences within genomes that direct the selective expression of ge...
GSE150849: microRNAs Restrain Proliferation in BRAFV600E Melanocytic Nevi
We conducted small RNA sequencing on low passage human melanocytes derived from melanocytic nevi and...
GSE80583: Chd5 regulates a ribosome biogenesis switch controlling neural cell fate specification
Cell fate specification of neural stem/progenitor cells (NSCs) is an intricate developmental process...
GSE80122: Mice carrying a human GLUD2 gene recapitulate aspects of human transcriptome and metabolome development
Whereas all mammals have one glutamate dehydrogenase gene (GLUD1), humans and apes carry an addition...
GSE77808: IL-15 activates mTOR and primes stress-activated gene-expression leading to prolonged anti-tumor capacity of NK cells
Treatment of hematological malignancies by adoptive transfer of activated natural killer (NK) cells ...
GSE87354: RNAseq analysis of Rpl13a-snoless and wild type islets
Purpose: To gain further mechanistic insight into phenotypic differences between wild type pancreati...
GSE75984: Persistent chromatin modifications induced by high fat diet
Obesity is a highly heritable complex disease that results from the interaction of multiple genetic ...
GSE80953 (mouse): Temporal comparison of transcriptomic alterations in human, mouse and rat primary B lymphocytes exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
RNA-Seq was used to analyze and compare temporal TCDD-induced gene expression changes in primary hum...
GSE84471: A Druggable TCF4- and BRD4-dependent Transcriptional Network Sustains Malignancy in Blastic Plasmacytoid Dendritic Cell Neoplasm (RNA-Seq)
Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive and largely incurable hematolo...
GSE109140: Valproic acid attenuates hyperglycemia induced complement and coagulation cascade gene expression
Diabetes is a multifactorial disorder and epigenetics changes are increasingly appreciated to influe...
GSE81842: Genome-wide comparison of gene expression level between leukemia stem cells in different tissues
Analysis of gene expression of leukemia stem cells (LSCs) in different tissues. The hypothesis is th...
GSE80120: Cell-specific gene expression profiling of warm-sensitive neurons
TRAP-seq gene expression profiling. GFP-L10a is expressed in BDNF+ or PACAP+ in preoptic area. Bdn...
GSE80444: RNA-Seq analysis of E15.5 pancreas of both whole body Nkx2.2 mutant embryos and endocrine progenitor specific Nkx2.2 mutant embryos
Aim: Transcriptional analysis of E15.5 whole pancreas of Nkx2.2-LacZ/LacZ embryos versus control and...
GSE84448: Global transcriptome profiling of the 889PF mouse pleural fluid disseminating tumour cell-derived cell line, with or without Cd109 knockdown
In order to determine the role of Cd109 in regulating metastatic ability and identify Cd109-dependen...
GSE83687: Mount Sinai Hospital (MSH) Population Specimen Collection and Profiling of Inflammatory Bowel Disease
This study focuses on inflammatory bowel disease gene expression profiling. Surgical specimens from ...
GSE140243: Studying diet induced liver carcinogenesis
The scope of this project is to study, using state-of-the-art systems in the liver following den ind...
GSE137361: Genome-wide transcriptome analysis of human papillomavirus type 16 infected primary keratinocytes [monolayer]
HPV alters the host transcriptional program to establish infection and complete its lifecycle. Infec...
GSE146626: Single-cell RNA-sequencing of CD4+ T cells from lung and draining lymph node of flu-infected mice
We performed a single-cell transcriptome analysis of pooled samples from lung and lymph node of 4-12...
GSE80716: Cooperation of Nutlin-3a and a Wip1 inhibitor to induce p53 activity
Targeting the Mdm2 oncoprotein by drugs has the potential of re-establishing p53 function and tumor ...
GSE147410: Sonic hedgehog accelerates DNA replication to cause replication stress promoting cancer initiation in medulloblastoma (RNA-Seq)
Cancer is a multi-stage disease caused by sequential mutations; however, the molecular mechanism gen...
GSE114007: Identification of transcription factors responsible for dysregulated networks in human osteoarthritis cartilage by global gene expression analysis
Objective:Osteoarthritis (OA) is the most prevalent joint disease. As disease-modifying therapies ar...
GSE99247: Differential Gene Expression and Pathway Analysis in Juvenile Nasopharyngeal Angiofibroma Using RNA-Sequencing
We have identified a set of differentially expressed genes in the juvenile nasopharyngeal angiofibro...
GSE123881: DDX5 promotes oncogene C3 and FABP1 expressions and drives intestinal inflammation and tumorigenesis
Tumorigenesis in different segments of the intestinal tract involves tissue-specific oncogenic drive...
GSE100339: The intestinal microbiota regulates body composition through NFIL3 and the circadian clock
The intestinal microbiota has been identified as an environmental factor that markedly impacts energ...