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Sequencing-based assays page 8
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GSE77188: Next generation sequencing based analysis of the embryonic (E15.5) transcriptome of wild type and 1-integrin-cKO lenses
1-integrin is the major -integrin subunit expressed in both lens epithelial and fiber cells. Our pre...
GSE81506: RNA-seq analysis of cultured neural stem cells (NSC) isolated from the subventricular zone and transformed lines GSC1 and GSC2 derived from these cells
Cultured NSC, GSC1 and GSC2 were sequenced to determine gene expression profiles and differentiation...
GSE73541: Neutrophils oppose uterine epithelial carcinogenesis via debridement of hypoxic tumor cells
Our study demonstrates that neutrophils infiltrate early-stage PTEN-deficient uterine tumors and opp...
GSE92274 (human): Comparative Transcriptomic Analysis of Hematopoietic System Across Species by Microwell-Seq
Traditional single-cell RNA-seq technologies have shown limitations for large scale experiments. Her...
GSE89574: Cbx3 Maintains Lineage Specificity During Neural Differentiation [RNA-seq]
Cbx3 (HP1) that is a member of the heterochromatin protein 1 family play important roles in developm...
GSE76309: Comparison of gender-biased liver gene expression from transgenic mice with chronic IFN gamma expression
We analyzed liver gene expression from male and female ARE-Del mice, which have prolonged and chroni...
GSE73631: A XEN-like state bridges somatic cells to pluripotency during chemical reprogramming
Pluripotent stem cells can be generated from somatic cells by using pure chemicals.However, the cell...
GSE70605: Single Cell Sequencing Identifies Key Epigenetic Regulators in Nuclear Transfer Mediated Reprogramming [RNA-seq]
Differentiated cell can be reprogrammed into totipotent embryo through somatic cell nuclear transfer...
GSE74161: Dnmt3a regulates myeloproliferation and liver-specific homing and expansion of hematopoietic stem and progenitor cells (RNA-Seq)
DNMT3A mutations are observed in myeloid malignancies, including myeloproliferative neoplasms (MPN),...
GSE113754: RNA-Seq analysis of Sleep deprivation in wildtype and Shank3 mutant mice
This dataset constitutes the first RNA-Seq study of gene expression following sleep deprivation in w...
GSE131126: RNA-seq in pancreatic cancer PANC1 cells
We report the the effect of PGAM1 succinylation on gene expression profiling. SOURCE: Xiaodong Zhang...
GSE75066: Genome-wide analysis of mitosis, early G1, late G1 and G2 in mouse pluripotent cells
We provide the genome-wide map of Esrrb binding in mitotic and asynchronous ES cells together with t...
GSE77891: RNA-SEQ analysis of E18.5 ALL Ret-positive (EGFP-labeled) male or female dorsal root ganglia neurons.
The goal of this set is to build expression data using FACS isolated Ret-positive cells harvested fr...
GSE71744: Lineage-specific functions of TET1 in the post-implantation mouse embryo
The TET dioxygenases erase mediate DNA dedemethylation in pre-implantation embryos and in primordial...
GSE74138: RNA-Seq analysis of 3 month old all Ret-positive (EGFP-labeled) dorsal root ganglia L345 or L6S1 neurons
The goal of this set is to build expression data using FACS isolated Ret-positive cells harvested fr...
GSE76125: Effect of mitochondria deficiency on senescence-associated gene expression
We used parkin overexpressing MRC5 fibroblasts to investigate the role of mitochondria deficiency on...
GSE75997: Gene expression changes upon Mll1 knockout in NUP98-HOXA9 transformed murine LSKs
We report Illumina next generation RNA sequencing (RNAseq) of NUP98-HOXA9 in vitro transformed murin...
GSE133831: Whole transcriptome analysis of human kidney cells after exposure to Ochratoxin A
Ochratoxin A (OTA) is a nephrotoxin that has been associated with kidney damages. The goal of this p...
GSE75778: Cerebellar RNA-Seq from ATXN1 Transgenic Mice Reveals SCA1 Disease Progression and Protection Pathways
SCA1, a fatal neurodegenerative disorder, is caused by a CAG expansion encoding a polyglutamine stre...
GSE79661: Partial loss of psychiatric risk gene Mir137 in mice causes repetitive behavior and impairs sociability and learning via increased Pde10a
Genetic analyses have linked microRNA-137 (MIR137) to neuropsychiatric disorders, including schizoph...
GSE77292: Ribosomal footprinting of CN34-Parental and CN34-LM1a
We used Illlumina Artseq Ribo Profile to perform ribosome footprinting on the above cell lines SOURC...
GSE77893: RNA-SEQ analysis of postnatal Ret-positive (EGFP-labeled) nociceptive (NaV1.8 population) dorsal root ganglia L345 or L6S1 neurons.
The goal of this set is to build expression data using FACS isolated Ret-positive cells (postnatal) ...
GSE113688: JunB defines functional and structural integrity of the epidermo-pilosebaceous unit in the skin
Here we identified JunB, a member of the AP-1 transcription factor family, regulated epidermal stem ...
GSE94078: Gene expression profiling of LSKSLAM cells in mice deficient for cholinergic fibers
RNASeq of LSKSLAM cells from Gfra2 WT vs KO mice SOURCE: Evangelia Diamanti (ed347@cam.ac.uk) - Gott...
GSE75616: Temporal transcriptome analysis of control and Zeb2 knockout mESC in pluripotency and in neural differentiation
To capture the Zeb2-dependent transcriptional changes in early cell state/fate decisions we performe...
GSE131834: Myeloid cells in liver and bone marrow acquire a functionally distinct inflammatory phenotype during obesity-related steatohepatitis
Liver myeloid leukocytes and their bone marrow precursors adapt a common and functionally relevant i...
GSE77513: Capturing the biology of mild versus severe disease in a pluripotent stem cell-based model of Familial Dysautonomia
Familial Dysautonomia is a genetic disease, however patietns with the same genotype present with mil...
GSE135312: RNA-seq analysis of CRISPR/Cas9 generated human BMPR2 deficient endothelial cell lines harboring mutations characteristic for hereditary pulmonary hypertension (HPAH)
Balanced TGF/BMP-signalling is essential for tissue formation and homeostasis. While gain in TGF sig...
GSE113719: Transcriptional respose to Wnt activation regulates the regenerative capacity of the murine postnatal cochlea
Purpose: Wnt activation can induce regeneration in the early postnatal cochlea, but the regenerative...
GSE81575: Next Generation Sequencing of 23116 MT (low Arid1a expression) vs AB-C1 and AB-C2 (high Arid1a expression) Transcriptomes
The goal of this study was to identify important genetic pathways that are altered in mammary tumor ...
GSE83358: FOXP1-SHQ1 deletion cooperates with PTEN deletion in oncogenesis
RNA-seq was carried out on prostate tumors from mice with prostate-conditional PTEN knockout with an...
GSE86549: Two functionally distinct human Pan3 isoforms regulate mRNA turnover across the transcriptome
Human Pan3 protein has two functionally distinct isoforms required for proper decay of mRNA across t...
GSE76931: The RNA binding protein IGF2BP3 promotes hematopoietic progenitor cell proliferation by targeting leukemogenic pathways
The goal of this study was to determine IGF2BP3 RNA targets in human B-cell Acute Lymphocitic Leukem...
GSE76093: RNAseq analysis of two independent stains of C57BL/6J-Plat-/- mice and wild-type C57BL/6J.
The ability to generate defined null mutations in mice revolutionized the analysis of gene function ...
GSE77315: Ribosomal footprinting of MDA-Parental and MDA-LM2
We used Illlumina Artseq Ribo Profile to perform ribosome footprinting on the above cell lines SOURC...
GSE129788: Single-cell transcriptomic profiling of the aging mouse brain
The mammalian brain is complex, with multiple cell types performing a variety of diverse functions, ...
GSE76498: KPC vs Wild Type Pancreatic Fibroblasts
These experiments aim to determine global gene expression patterns in WT vs KPC isolated pancreatic ...
GSE73562: Gene expression analysis to identify target genes activated after preBCR signaling
The sequential activation of distinct developmental gene networks governs the ultimate identity of a...
GSE90019: Analysis of transcriptional and epigentic changes induced by loss of Phf8 [RNA-seq]
Phf8 is a histone demethylase with links to human behavior. Here we have performed a transcriptional...
GSE76626: Characterization of EZH2-deficient human embryonic stem cells [ChIP-seq and bulk RNA-seq]
Here we analyze histone modifications and transcriptome profiles of EZH2-deficient human embroynic s...
GSE81579: Transcriptome analysis of human cumulus cells reveals hypoxia as the main determinant of follicular senescence.
RNA sequencing profiling of cumulus cells revealed that the follicles of older women have a compromi...
GSE81257: Nfib promotes Metastasis through a Widespread Increase in Chromatin Accessibility [RNA-seq]
We describe Nfib as an important regulator of chromatin accessibility in SCLC. SOURCE: William Green...
GSE90053 (mouse): Species-Specific Developmental Timing is Maintained by Pluripotent Stem Cells Ex Utero
We performed whole transcriptome RNA sequencing experiments on two sets of differentiation time cour...
GSE86590: A BAT-enriched RNA binding protein, Ybx2, regulates cold-induced brown fat activation by stabilizing Pgc1 mRNA
To study the role of Ybx2 in brown fat activity, we performed the RNA-seq data for wildtype and Ybx2...
GSE72238: Genome-wide H2B monoubiquitination regulates gene expression by coordinating H3K4me3 and H3K27me3 [RNA-Seq Data Set]
Gene body-associated monoubiquitination of H2B (H2Bub1) coupled with promoter-associated active hist...
GSE81576: Gene expression profiling of Eed knockout and Ezh2 knockout small intestinal crypts [RNA-seq]
Polycomb-mediated gene repression plays an important role in adult stem cell maintenance. We knocked...
GSE73503: Transcriptome profiling in knock-in mouse models of Huntington's disease [Hippocampus_mRNA]
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that is characterized ...
GSE76711: Stromal cells secrete exosomes carrying specific molecular signature involved in the support of Hematopoietic Stem and Progenitor Cells
Purpose: The study focused on the RNA content of supportive (AFT024) and non supportive (BFC012) str...
GSE77374: RNA-seq data from murine eGFP+ relbfl/flnfkb2fl/flCg1-Cre and Cg1-Cre splenic germinal center B cells purified by fluorescent activated cell sorting.
RNA-seq analysis of murine eGFP+ relbfl/flnfkb2fl/flCg1-Cre and Cg1-Cre splenic germinal center B ce...
GSE72590: Transcriptomic characterization of the impact of 2'-fucosyllactose supplementation on intestinal adaptation following ileocecal resection.
Purpose: To identify the impact of 2'-FL supplementation on adaptive response following extensive in...
GSE77569: RNA-sequencing reveals transcriptional up-regulation of Trem2 in response to bexarotene treatment
High throughput massively parallel sequencing on mRNA libraries generated from cortices of bexaroten...
GSE76733: Genome-wide profiling of 2 month vs >6 month old muscle Treg cells
We report age-related gene expression of Treg cells isolated from injured muscle and spleen. Male C5...
GSE77003: Regulation of Promoter and Enhancer Histone Landscape by DNA Methylation in Embryonic Stem Cells (RNA-seq)
In this study, we mapped modification of lysine 4 and lysine 27 of histone H3 genome-wide in a serie...
GSE74679: Analysis of transcriptome changes in Kmt2d deletion in cardiac mesoderm, anterior heart field precursors and cardiomyocytes
KMT2D is required in the cardiac mesoderm, anterior heart field precursors and cardiomyocytes. Kmt2d...
GSE88949: Effects of NIK activation on the self-renewal of hematopoietic stem cells
Comparison of transcriptome between control and NIK-activated hematopoietic stem cells SOURCE: Thoma...
GSE98274: RNA-Seq of SHEP TET21N cells upon Doxorubicin treatment
MYCN-high and MYCN-low neuroblastoma cells differ in their responses to Doxorubicin treatment. To ex...
GSE142603: Lack of RAN-mediated toxicity in Huntingtons disease knock-in mice
Identification of repeat-associated non-AUG (RAN) translation in trinucleotide (CAG) repeat diseases...
GSE71734: RNA-seq data of intestinal epithelial cells
We report that adhesion of microbes to intestinal epithelial cells is a critical cue for Th17 induct...
GSE70249: Identification of chemicals that mimic transcriptional changes associated with autism, brain aging and neurodegeneration
Environmental factors, including pesticides, have been linked to autism and neurodegeneration risk u...
GSE76487: MBNL1-dependent modulation of gene expression in MDA-MB-231 breast cancer cells
To identify MBNL1-dependent changes in gene expression, MDA-MB-231 cells expressing either control o...
GSE77007: Quantitative Analysis of mRNA expression in calvaria tissue from control and Med23-/- vs. wild type and Runx2+/- mice through Next Generation Sequencing
We sequenced mRNA from 12 single newborn mouse calvaria tissues ( from 3 control and 3 Med23-/- cKO ...
GSE76483: Simultaneous profiling of transcriptome and DNA methylome from a single cell
We developed a new single cell sequencing method to simultaneously sequence methylome and transcript...
GSE77462: Searching for target genes of miR-508/509/506/514 in HCT116 cells
To elucidate whether miR-508/508/509/514 plays a role in colorectal cancer tumorigenesis, RNA-seq ...
GSE79814: Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-Derived Mesenchymal Stem Cells (RNA-seq)
Terminal differentiation of multipotent stem cells is achieved through a coordinated cascade of acti...
GSE126446: Transcriptome analysis of reticulated platelets reveals a prothrombotic profile [mRNA-Seq]
To compare immature and mature platelet transcriptome; Methods: reticulated or immature platelets(RP...
GSE72550: Epigenomic Landscapes of Retinal Rods and Cones
Both rod and cone photoreceptors are critical for mammalian vision yet they have important functiona...
GSE79209: Airway epithelial cells from smokers with and without bronchial premalignant lesions
While lung cancer is the leading cause of cancer death in the US, we have a limited understanding of...
GSE74724: Translational profiling identifies a cascade of damage initiated in motor neurons and spreading to glia in mutant SOD1-mediated ALS
Ubiquitous expression of ALS-causing mutations in superoxide dismutase 1 (SOD1) provoke non-cell aut...
GSE79374: Single-cell RNAseq of mouse brain tissues across 3 developmental time points
Brains were harvested from 2-month-old adult, p12 day old mice and e18.5 day mice embryo. Brain regi...
GSE76682: RNA-seq expression data from EB-HSPC after AM580 treatment compated to DMSO-trated and FL-HSPCs
RA signalling regulated endothelial to hematopoietic transition and HSC generation. SOURCE: Hanna,Ka...
GSE79791: BMP (Bone morphogenetic protein) signaling network regulates mesenchymal stem cell lineage commitment during tooth development
Mesenchymal stem cells (MSCs) are multipotent progenitor cells present in various mesenchymal tissue...
GSE78272: Transcriptome profiling in knock-in mouse models of Huntington's disease (cortex_mRNA).
Huntington's disease (HD) is an autosomal dominant neurodegenerative disorder that is characterized ...
GSE78271: RNA-SEQ assay for wild type and CRISPR induced endoglin knockout human pulmonary artery smooth muscle cells (PASMC)
The goal of this study is to investigate the differential transcripted genes affected by CRISPR indu...
GSE79210: Airway epithelial cells from high-risk subjects obtained via multiple bronchoscopy procedures to follow bronchial premalignant lesions as part of lung cancer screening
While lung cancer is the leading cause of cancer death in the US, we have a limited understanding of...
GSE76017: Transcriptomic profiling of alpha, beta, and delta cell populations provides new insights into the role of ghrelin in the pancreas
Intra-islet crosstalk between islet cells is critical in orchestrating the bodys response to changes...
GSE77514: RNA sequencing identifies differentially expressed genes in embryonic cardiomyocytes following knockdown of DNMT3a or DNMT3b expression
Purpose: This study aims to identify the differentially expressed genes in embryonic cardiomyocytes ...
GSE71802: RNA-Seq: assessment of transcript level analysis tools [seq]
This study uses spiked-in transcript in order to compares various bioinformatics approaches and tool...
GSE79824: Transcriptome analysis of Shank2 mutant mice
Autism spectrum disorders (ASDs) are a group of developmental disorders that cause variable and hete...
GSE125527: Single-Cell Analyses Elucidate the Cellular and Molecular Landscape of Ulcerative Colitis
Inflammatory bowel disease (IBD) encompasses a spectrum of complex intestinal disorders characterize...
GSE73391: Nuclear RNA in the nervous system
Background: Recent characterization of the transcriptional landscape of cell lines and whole tissues...
GSE100331: Myosin Heavy Chain-embryonic is a crucial regulator of skeletal muscle development and differentiation.
mRNA from 4 different muscles from control and Myosin heavy chain-embryonic knockout neonate mice we...
GSE78040 (mouse): Reversible methylation of m6Am in the 5 cap controls mRNA stability
Internal bases in mRNA can be subjected to modifications that influence the fate of mRNA in cells. O...
GSE78499: Transcriptome analysis of aging mouse meibomian glands
RNA-sequencing of young and old mouse eyelids identified a number of signaling pathways, including F...
GSE127260: Single cell RNA-seq identifies cell diversity in embryonic salivary glands [Bulk RNA-seq]
Our single-cell and bulk transcriptome analyses revealed striking molecular heterogeneity in the mes...
GSE76567: Transcriptomic Analysis of the Hippocampus from Six Inbred Strains of Mice Suggests Basis for Sex-Specific Susceptibility and Severity of Neurological Disorders
Identifying sex differences in gene expression within the brain is critical for determining why mult...
GSE76602: Tumor suppressor role of Ezh2 in an NRASQ61K driven model of Early T-cell Precursor Acute Lymphoblastic Leukemia (RNA-Seq)
Purpose: To characterize transcriptional changes associated with homozygous inactivation the Polycom...
GSE84759: LIM-Domain-Binding 1 maintains the terminally-differentiated state of pancreatic -cells
Utilize high-throughput transcriptomic and cistromic analysis to determine the functional requiremen...
GSE127683: Single cell RNA-seq analysis of hair cell regeneration in the mammalian vestibular system and its potentiation by Atoh1
We used single cell RNA-seq to probe the transcriptional responses of utricle supporting cells to da...
GSE79812: Microglia development follows a stepwise program to regulate brain homeostasis - RNA seq
Microglia play important roles in life-long brain maintenance and in pathology, but are also crucial...
GSE114981 (human): Activation of HOTTIP lncRNA perturbs HSC function leading to AML like disease
We found that posterior HOXA-associated HOTTIP lncRNA is aberrantly activated in MLL-rearranged AMLs...
GSE76606: Asynchronous combinatorial action of four regulatory factors activates Bcl11b for T cell commitment
During T cell development, multipotent progenitors relinquish competence for other fates and commit ...
GSE79818: Microglia development follows a stepwise program to regulate brain homeostasis - Single Cell RNA-seq
Microglia play important roles in life-long brain maintenance and in pathology, but are also crucial...
GSE78725: Transcriptional Regulationand Chromatin Dynamics inHuman Epithelial Cell Differentiation (RNA-seq)
Transcriptional profiling of KP and DK through RNA-seq SOURCE: Luca Petiti (luca.petiti@itb.cnr.it) ...
GSE90516: RNA-Seq of mESCs based on sex chromosome complement
RNA-Seq was performed on mESCs generated from F1 hybrids from reciprocal crosses of C57BL/6J and CAS...
GSE73787: Disruption of Ah Receptor Signaling during Mouse Development Leads to Abnormal Cardiac Structure and Function in the Adult
The Developmental Origins of Health and Disease (DOHaD) Theory proposes that the environment encount...
GSE78078 (mouse): miR-126 Orchestrates an Oncogenic Program in B-Cell Precursor Acute Lymphoblastic Leukemia
MicroRNA (miRNA)-126 is a known regulator of hematopoietic stem cell quiescence. We engineered murin...
GSE79863: Next Generation Sequencing Facilitates Quantitative Analysis of germ cell RA signaling mutant and control THY1+ spermatogonia Transcriptomes
Purpose: The goal of this sequencing is to investigate alterations in gene expression that result f...
GSE78127: Epigenetic Profiles Signify Cell Fate Plasticity in Unipotent Spermatogonial Stem and Progenitor Cells (RNA-Seq)
Mammalian spermatogonial stem cells (SSCs) spontaneously convert to multipotent adult spermatogonial...
GSE79861: ATXN7L3 And ENY2 Coordinate Activity Of Multiple H2B Deubiquitinases Important For Cellular Proliferation And Tumor Growth [RNA-Seq]
We report that H2B deubiquitinating enzymes USP22, USP27x and USP51 have both unique and overlapping...
GSE124939: Hypersensitive interferon responses in lupus keratinocytes reveal key mechanistic determinants in cutaneous lupus
SLE patients exhibit increased interferon signatures in their skin secondary to increased production...