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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Mycobacterium tuberculosissuccess as a pathogen comes from itsability to evade degradation by macrop...
Massive expansion of erythroid progenitor cells is essential for surviving anemic stress. Research...
We report the transcriptomes of human choriocarcinoma cell lines JEG3 and BeWo in order to provide i...
To investigate the effect of Tet2 deficiency on the gene expression in mouse kidney tissues under ba...
Microexons represent the most highly conserved class of alternative splicing, yet their functions ar...
To explore the mechanisms through which GLUT1 controls EC function, we compared transcriptomic alter...
Purpose: MicroRNA-148a regulates the differentiation of dendritic cells. The goals of this study are...
We performed a thorough study to analyze the epigenetic regulation of genes enabling programmed cell...
Cone photoreceptor cell death in inherited retinal diseases, such as Retinitis Pigmentosa (RP), lead...
TRAP translational profiling is a method that allows investigators to genetically characterize speci...
PC9 cells (untreated or treated with 4D combo) were harvested (in trizol) 48h or 72h after 4D combo ...
To identify the idea that deficiency of Uhrf1 in macrophages aggravated the intestinal inflammation,...
The circadian clock and rhythmic food intake are both important regulators of rhythmic gene expressi...
Purpose: Fat storage in adult mammals is a highly regulated process that involves the mobilization o...
It remains unknown how polyglutamine expansion in widely expressed proteins can cause selective neur...
Abstract: The intestinal epithelium is replaced weekly by non-quiescent stem cells with kinetics tha...
Airway macrophages (AMs) are the most abundant leukocytes in the healthy airway lumen and have a hig...
A clinical trial assessed the cutaneous immune response and short-term efficacy, safety, and tolerab...
To elucidate roles that Nrf2 plays in regulating adaptive responses to the space stress, one month-l...
Phenotypic plasticity and partial EMT underlie local invasion and distant metastasis in colon cancer...
In sub-Saharan Africa, endemic Kaposis sarcoma (EnKS) is still prevalent despite high incidence of e...
Tumour cells adapt to nutrient deprivation in vivo, yet strategies targeting the nutrient poor micro...
Ovarian cancer has the highest mortality in gynecologic cancers and most patients are diagnosed in a...
The aim of the project is to characterize the heterogeneity of murine plasmacytoid dendritic cells (...
This phase 1b, single-center, double-blind study evaluated safety, efficacy, and effect on molecular...
We report here the effect of RelB ablation in CD11c+ cells on the Treg compartment accross various o...
Purpose: To understand how dexamethasone has beneficial effects on reducing mucus production but inh...
Transcriptional profiling of E5.5 and E6.5 wild type and Blimp1 mutant decidua was performed using R...
The goal of this study was to understand the mechanisms of miRNA regulation of the transcriptome of ...
Fibrosis, or the accumulation of extracellular matrix, causes loss of organ function and is a common...
To understand the transcriptional responses induced by LIGHT in esophageal fibroblasts and compare t...
Using 3-end RNA-seq followed by digital gene expression analyses we assessed genes that change expre...
Purpose: Identification of osteoclast derived coupling factors using Denosumab as a biological prob...
Linker histone H1 proteins bind to nucleosomes and cause chromatin compaction, although little is kn...
Genetic-driven deregulation of the Wnt pathway is crucial but not sufficient for colorectal cancer (...
Humoral immunity in mammals relies on the function of two developmentally and functionally distinct...
von Hippel-Lindau (VHL) is a critical tumor suppres- sor in clear cell renal cell carcinomas (ccRCCs...
Although cells of the immune system experience force and pressure throughout their lifecycle, almost...
Multiple sclerosis is a chronic autoimmune disease driven by pathogenic Th17 cells. Here, we dissect...
The physiological functions of the HAT/DESC sub-family of membrane-anchored serine proteases are poo...
To determine transcriptome changes in pre-disease onset motor neurons induced by the GarsC201R mutat...
TRAP translational profiling is a method that allows investigators to genetically characterize speci...
Neocortex expansion is largely based on the proliferative capacity of basal progenitors (BPs), which...
Objective: The E2F1 transcription factor regulates the expression of genes involved in cell prolifer...
Esophageal squamous cell carcinoma (OSCC) is a lethal digestive tract malignancy with limited effect...
Ketone bodies are essential alternative fuels that allow humans to survive periods of glucose scarci...
Malignant peripheral nerve sheath tumors (MPNSTs) are deadly sarcomas that lack effective therapies....
Characterisation of blood and lung global transcriptional responses to Mycobacterium tuberculosis in...
The Lgr5 receptor is a marker of intestinal stem cells (ISCs) that regulates Wnt/b-catenin signaling...
Anterior vaginal prolapse, as the most common form of POP, severely affect womens physical and menta...
We report that Jagn1-deficiency is associated with alterations in the ER of antibody-producing cells...
SC-beta cells were infected with CVB and collected over a time course. SOURCE: Pranitha Vangala (pra...
Heterogeneous nuclear ribonucleoproteins (hnRNPs) are a group of functionally versatile proteins tha...
Subcellular RNA-seq datasets are used for genome-wide RNA localization analysis. We find different s...
Purpose: Identification of osteoclast derived coupling factors using Denosumab as a biological prob...
Cancer cells exploit the epithelial-to-mesenchymal transition (EMT) program toward metastasis. Cytos...
Purpose: MBD5-Associated Neurodevelopmental Disorder (MAND) is an Autism Spectrum Disorder (ASD) dis...
An antisense oligonucleotide (ASO) against E3 ubiquitin ligase IDOL in the brain significantly decre...
Brain Derived Neurotrophic Factor (BDNF) is a potent modulator of brain synaptic plasticity. Signali...
Lineage plasticity is a prominent feature of pancreatic ductal adenocarcinoma (PDA) cells, which can...
We compared expression profiles of immature myeloid cells from PARP1CKO and PARP2CKO mice with their...
TRAP translational profiling is a method that allows investigators to genetically characterize speci...
Mosaic-variegated aneuploidy (MVA) syndrome is a rare childhood disorder characterized by biallelic ...
There is substantial evidence that many cancers, including human breast cancer are hierarchically or...
To explore the mechanisms through which GLUT1 controls EC function, we compared transcriptomic alter...
Gastric organoids were manipulated to knockout p53 SOURCE: Chunyang Bao (cy.bao@outlook.com) - Dana...
We have used in vivo selection to isolate GPX4 knockout 786-O cells that have evaded ferroptosis in ...
Transcriptome analysis has uncovered a series of long noncoding RNAs (lncRNAs) transcribed during ce...
TrkB with its ligand, brain-derived neurotrophic factor (BDNF), are overexpressed in the majority of...
To analyse gene expression differences between HCT 116p53-/- and HCT 116p53-/- RPL3 KO and/or during...
94T778 cells were exposed to nutlin-3a, palbociclib and tunicamycin. Cells were harvested during the...
Mammalian cells respond to insufficient oxygen through transcriptional regulators called hypoxia-ind...
The highly heterogeneous nature of the kidney's tubular epithelium has made it challenging to identi...
To determine the roles of IFI16-p53 interaction during H9-trilineage specification, we performed ChI...
In this study we introduce an enhanced CRISPR-based transcriptional repressor to reprogram immune ho...
Purpose: The goal of this study is to compare the expression profile of wild type and Tbx1-nmf219/nm...
Anti-viral CD8 T cell responses are characterized by an initial activation/priming of T lymphocytes ...
MicroRNAs function is defined by the targets it regulates. Despite miRNAs crucial role in various ce...
To identify GC-related RNAs, we used five GC patients fresh tumor tissues and paired adjacent non-tu...
The Myocardial Applied Genomics Network (MAGNet; www.med.upenn.edu/magnet), collects and banks human...
LMO2 is an oncogenic transcription factor that is frequently overexpressed due to chromosomal abnorm...
Intellectual disability affects 2-3% of the general population. Related to the nature vs nurture hyp...
Fused in sarcoma (FUS) encodes a low complexity RNA-binding protein with diverse roles in transcript...
The remarkable plasticity of Schwann cells (SCs) is essential for nerve regeneration but also contri...
Merkel cell carcinoma (MCC) is a highly aggressive, neuroendocrine skin cancer that lacks actionable...
This RNA-Seq experiment aims at unraveling the sets of genes that may be deregulated in a specific s...
Chronic stress (CMS) affects many brain functions and is a major risk factor for the development of ...
The current study is focused on elucidating the effect of acute alcohol challenge on esophageal epit...
mononuclear cells from AS patients pre and post treatment. We found 656 differentially expressed gen...
m6A-seq was performed on 4 brain regions (cortex, cerebellum, hypothalmus and hippocampus) of 2 week...
ARID1B KO in liver leads to minimal gene expression changes, whereas ARID1A/1B DKO leads to global g...
TRAP translational profiling is a method that allows investigators to genetically characterize speci...
Alzheimers disease (AD) is characterized by the selective vulnerability of specific neuronal populat...
CCL5 (also known as RANTES) was originally known to be important to recruit memory T cells to infect...
surgery samples of patients at early and late timepoints of a pancreatectomy SOURCE: Reiner Schneide...
Dedifferentiation of pancreatic beta cells may reduce islet function in type 2 diabetes (T2D). Howev...
Uncoupling protein-1 (UCP1) plays a central role in energy dissipation in brown adipose tissue (BAT)...
The identification of miRNA targets by Ago2-CLIP methods has provided major insights into the biolog...
Methyltransferase-like 3 (METTL3) and 14 (METTL14) are core subunits of the methyltransferase comple...
Trained Immunity (TRIM) is the phenomenon whereby innate immune cells such as monocytes or macrophag...