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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
We performed RNA sequencing in isogenic models of COX-1 proficient (OV3/SCR) and COX-1 deficient (OV...
We performed genome-wide RNA-seq and ChrRNA-seq experiments in T47D cell lines after PADI2 knock do...
NGS analysis of transcriptomes of MyD88 sufficient vs deficient GC B cells SOURCE: Eric,Joseph,Wigto...
The efficacy of cancer treatments have improved constantly in the last decade. However, therapeutic ...
Aberrant expression of cancer genes and non-canonical RNA species is a hallmark of cancer. However, ...
GC-like structures within iBALT serve as a distinct niche that independently support the maturation ...
Nucleoporins (Nups) are a family of proteins best known as the constituent building blocks of nuclea...
Estrogens play an important role in breast cancer (BC) development and progression, where the two is...
The cellular transcriptome of C57BL/6 mouse lungs was profiled by mRNA-Seq analysis at multiple time...
RNA sequencing of wild-type or Interferon Alpha receptor 1 Knockout MEF cells treated with DMSO or t...
We performed deep RNA sequencing and systematically analyzed the global gene expression profiles of ...
MicroRNAs (miRNAs) are important regulators and potential therapeutic targets of metabolic disease. ...
We profile the cell line expression of 279 circRNAs, that are highly expressed across 457 bladder ca...
Purpose: Compare the RNA content of apoptotic human umbilical vein endothelial cells (HUVECs)-releas...
Organismal development requires the precise coordination of genetic programs to regulate cell fate a...
The CCR4-NOT complex, bearing poly(A) deadenylation activity, is a highly conserved regulator that i...
Purpose: While type I interferons (IFN) are important for control of viral replication, we see that,...
Leukemia stem cells (LSCs) are found in most aggressive myeloid diseases and contribute to therapeut...
We found that posterior HOXA-associated HOTTIP lncRNA is aberrantly activated in MLL-rearranged AMLs...
Purpose: The aim of this study is to identify genes that are under the transcriptional control of th...
Cancer is a heterocellular disease composed of tumor cells and stromal cells. Although stromal cells...
We used two different influenza viruses lacking either PB1 or HA to differentiate the antiviral resp...
PDGF and FGF treatment in E13.5 MEPMs. 4 hr PDGF treated MEPMs (3 replicates), 4 hr FGF treated MEP...
We provide here the alterations in gene expression profiles of HepaRG cells, a validated model for c...
We report the effect of a potent pharmacological inhibition of ASBT in mdr2 -/- mice, compared to ge...
Despite its biological importance, transfer RNA (tRNA) could not be adequately sequenced due to the ...
We report AICDA facilitates nave pluripotency of mouse iPSCs by suppressing FGF/ERK signaling. In th...
Identification of cyclical expressed coding and non-codind genes during the circadian rhythm in NIH3...
Analysis of Lin-c-Kit+Sca-1- haematopoietic stem cells (HSCs) expressing the Nup98-HoxD13 (NHD13) fu...
We perform RNA-seq on matched orthotopic murine primary and metastatic prostate cancer samples to id...
We compare the performance of two library preparation protocols (poly(A) and exome capture) in in vi...
Precisely how AID is recruited to these off-target sites is not entirely understood. To gain further...
Identify genes which are induced in wild type, crel ko, and relbcrle dbko B cells under BAFF stimul...
We profiled a RNA-seq on ICR mouse testis. We found that AOS can improve the expression of the gene...
We used micro-dissection techniques and/or FACS to isolate cell types from the developing and adult ...
Unrestrained receptor tyrosine kinase (RTK) signaling and epigenetic deregulation are root causes of...
In mammals, DNA methylation is essential for protecting repetitive sequences from aberrant transcrip...
Liver X Receptors (LXR and ) are ligand-activated transcription factors that play a key role in the ...
The Microrchidia (Morc) family of GHKL ATPases are present in a wide variety of prokaryotic and euka...
These findings reveal the global chromatin response to UV damage and its relation to impaired gene r...
Gene regulation in mammals involves a complex interplay between promoter and distal regulatory eleme...
During embryonic germ cell development in mice, transposon-enriched, piwi-interacting RNAs (piRNAs) ...
Genomic imprinting is a critical developmental process characteristic of parent-of-origin- specific ...
We report the application of RNA-seq to identify the mRNA targets of 4 herpesviral endonucleases and...
Analysis of Nestin-GFP+ pericytes flow sorted from 3-day-old mouse cutaneous adipose tissue, compari...
Purpose: To study the mechanisms involved in the regulation by NFIX on neural stem cell development ...
Selenium deficiency in mice is associated with pro-longevity mechanisms due to reduced amino acid le...
A diverse pool of RNAs remain encapsulated within the transcriptionally and translationally silent s...
RNA-SEQ profiling of mouse whole midbrain and dopaminergic neurons from the mouse mid-brain SOURCE: ...
Transfer RNA (tRNA) is a central component of protein synthesis and cell signaling network. One sali...
The cranial neural crest cells are pluripotent cells that provide head skeletogenic mesenchyme and a...
A sheet of choroid plexus epithelial cells extends into each cerebral ventricle and secretes signali...
We investigated the effect of SIRT6-knockout on gene expression and H3K4me3 modification profile in ...
We aim to identify differentially expressed genes between AML patient samples and normal hematopoeit...
DNA methylation is an epigenetic mark thought to be robust to environmental perturbations on a short...
The 3q21q26 mice harboring a transgene recapitulating GATA2 enhancer-drived EVI1 overexpression in i...
We used single cell RNA sequencing on 466 cells to capture the cellular complexity of the adult and ...
This study aims to investigate the role of microRNA-30c on hepatic and metabolic gene expression and...
RNA-seq of bone marrow samples of chronic myelomonocytic leukemia (CMML) patients and healthy donor...
Mutations within genes encoding spliceosomal proteins are the most common class of mutations in pati...
We established a neuron-specific Argonaute2:GFP-RNA immunoprecipitation followed by high throughput ...
3T3L1 preadipocytes were treated with DMSO control and Nutlin-3a (prepared in DMSO) and total RNA e...
Examination of 2 different developmental time points (P0 and P7) in the cortex of control and Foxp1 ...
Ionizing radiation (IR) has long been associated with reduced hematopoietic function and increased m...
Skin and its appendages such as hair follicle and sweat gland are formed by Keratin-5 expressing (Kr...
In this study we performed RNA sequencing to determine and compare the transcriptome of regulatory T...
In the cerebral cortex, projection neurons and interneurons work coordinately to establish functiona...
Single cell genome, DNA methylome, and transcriptome sequencing has been achieved separately. Howeve...
Purpose: The purpose of this study is to identify novel regulator of B cell tolerance to gut associa...
Macrophages reside in essentially all tissues of the body and play key roles in innate and adaptive ...
Prostaglandins are involved in maintaining tissue integrity under homeostatic conditions. However, i...
Xbp1 is an important regulator of unfolded protein response and lipid metabolism. Its dyregulation h...
Purpose: In this study, we compared transcriptome profiling (RNA-seq) between normal mouse embryonic...
We set out to identify differences in the transcriptome influenced by knockout of the transcription ...
InfluenzaAvirus (IAV) infection causes an acute respiratory disease characterized by a strong inflam...
NA SOURCE:
DNA methylation is an epigenetic mark thought to be robust to environmental perturbations on a short...
The helix-loop-helix transcription factor Early B-Cell Factor 2 (EBF2) is required for the different...
We recently identified ISRIB as a potent inhibitor of the integrated stress response (ISR). ISRIB re...
RNA sequencing was performed comparing sciatic nerves of Schwann cell specific DICER mutants with SC...
To determine the global effects of ASCT2 inhibition, we used next generation sequencing to determine...
Here we report the derivation of human PBTESCs from polar body transfer resconstructed embryos. We u...
By using a genetically accurate mouse model, we demonstrate that endogenous expression of oncogenic ...
Cell-based models of many neurological and psychiatric diseases, established by reprogramming patien...
The spinal cord and mesodermal tissues of the trunk such as the vertebral column and skeletal muscul...
The aim of the study is to identify AR target gens in LNCaP cells SOURCE: Eric Metzger Uniklinik-Fre...
Induced MYC expression by CRISPRi targeting PVT1 was validated by RNA-seq SOURCE: Howard,Y.,Chang (h...
The evolutionary expansion of the human neocortex reflects increased amplification of basal progenit...
RNA-Sequencing analysis of 18 papillary thyroid carcinoma biopsies and of 4 healthy donors' thyroids...
The antibody gene mutator AID promiscuously damages oncogenes and B cell identity genes leading to c...
Tissue- and cell-type specific regulators of alternative splicing (AS) are an essential layer of pos...
Cell-type specific RNA-seq is a powerful approach for unravelling molecular processes of endometrial...
The histological grade of carcinomas describes the ability of tumor cells to organize differentiated...
Hematopoietic stem cells (HSCs) inhabit distinct microenvironments within the adult bone marrow (BM)...
Spinal muscular atrophy (SMA) is a neuromuscular disorder caused by mutations of the survival of mot...
Senescent cells accumulate in many ageing-associated diseases such as pulmonary fibrosis, and target...
To investigate response or resistance to endocrine therapy, mice with targeted over-expression of Es...
Rationale: MicroRNAs play key roles in hypertrophic stress responses. miR-378(-3p) is a highly abund...
The addressable pocket of a target protein is often not functionally relevant. This is particularly ...
This study was aimed at understanding the genome-wide binding and regulatory role of the DAXX transc...