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We performed RNAseq analysis to determine the effect of ClpP-deletion on cumulus cells global gene e...
A validated animal model would assist with research on the immunological consequences of the chronic...
This study used Illumina RNA-sequencing to examine transcriptomic profile of mice with Klf5 knockout...
Eosinophils are highly abundant throughout the gastrointestinal tract. However, their function in ba...
The objective of this study is to identify a gene set to predict recurrence of colorectal cancer (CR...
BRD4 plays a major role in the transcription networks orchestrated by androgen receptor (AR) in cast...
To investigate the role of Nir in epidermis during embryogenesis, we crossed mice harboring conditio...
Both the amygdala and the bed nucleus of the stria terminalis (BNST) have been implicated in maladap...
Mouse nave pluripotent stem cells (ESC) can contribute to all embryonic tissues and the germline, bu...
Determination of the molecular properties of genetically targeted cell types has led to fundamental ...
RNA-seq was performed using Thy1- and c-Kit+ spermatogonia from 7-days-old PRC1ctrl or dKO mice. SOU...
SPT6, encoded by the SUPT6H in humans and Supt6 in mice, respectively, is a conserved histone chaper...
Mammary glands were collected from 8 pubescent (4.7-4.9 week-old) female mice and 8 adult (10 week o...
RNA seq was used to compare the expression profile of macrophages in presence and absense of mast ce...
We analyzed changes in abundance of RNAs in mouse embryonic fibroblasts (MEF) from wild type and p53...
Foxp3+CD4+ regulatory T cells (Tregs) play important roles in controlling both homeostatic processes...
The gene regulatory mechanisms that steer neural stem cells towards astrocytes during brain developm...
Inhibition of Nonmuscle Myosin II impairs mesenchymal gene expression during epicardial EMT. SOURCE:...
Excision of the N-terminal initiator methionine (iMet) residue from nascent peptide chains is an ess...
We utilized translating ribosome affinity purification (TRAP) coupled with RNA sequencing to examine...
We examined the transcriptional changes in mouse lungs induced by house dust mite (HDM), D.f. extrac...
Activated hepatic stellate cells orchestrate scar formation during fibrotic liver injury. Recent evi...
Conventional 2-D differentiation from pluripotency fails to recapitulate cell interactions occurring...
Abstract Background: Histone deacetylase (HDAC) inhibition has shown some efficacy in urothelial ca...
The goal of this study was to compare transcriptome of HeLa cells with or without TFIIB knockdown fo...
Inhibitory receptors (Irs) are pivotal in controlling T cell homeostasis because of their intrinsic ...
Mounting evidence indicates that small ubiquitin-like modifier (SUMO) conjugation regulates a wide r...
Single-cell RNA sequencing of mouse amygdala using Drop-Seq SOURCE: Ye,Emily,Wu UCLA
We combine extensive profiling of single-cell gene expression (scRNA-seq of 39,263 cells) and chroma...
Comparative RNA and small RNA sequencing analysis of in vitro differentiated like cells, in vivo ma...
Monocytes are circulating mononuclear phagocytes, poised to extravasate to sites of inflammation and...
T-cell acute lymphoblastic leukaemia (T-ALL) is a disease characterized by the uncontrolled clonal p...
Asthma is one of the most common chronic diseases among pregnant women, and symptoms often worsen du...
We performed spatial transcriptome analysis on cryosections of gastrulating embryos from E6.5 to E7....
Here, using a modified STRT-seq protocol, we analyzed the large intestine (LI) from two adults.In de...
Mice were inoculated with Listeria by i.p. injection on days 0 and 11. On day 18, FSC(high)CD4(+)CD8...
We report the effect of Morc2b inactivation on the transcriptome of testes at postnatal day 12 (PND1...
The T cell compartment must contain diversity in both T cell receptor (TCR) repertoire and cell stat...
We have ectopically expressed two V5-tagged homeobox genes and a control plasmid in mouse embryonic ...
Bladder cancer is the fifth most prevalent cancer in the U.S., yet is understudied and relatively la...
Aging is associated with functional decline of hematopoietic stem cells (HSC) as well as an increase...
To gain in depth transcriptional information about the two subsets of effector Tregs, we performed R...
High mobility group (HMG) proteins are of similar size as histones with HMGA1 and HMGA2 being partic...
Purpose: Identify genes implicated in resistance to H. polygyrus; Method: RNA was extracted from duo...
Past studies have identified hepatic tumors with mixed hepatocellular carcinoma (HCC) and cholangioc...
We isolated RNAs from hematopoietic stem and progenitor cells (HSPCs). We compared two groups of mic...
Comparison of transcriptome between control and Ezh2-deficient follicular helper T cells SOURCE: Hai...
Rett syndrome (RTT) is an X-linked neurodevelopmental disorder caused by mutations in the transcript...
Alzheimer's disease (AD) is a detrimental neurodegenerative disease with no effective treatments. Du...
Purpose: The goal of this study is to get a comprehensive evaluation of the transcriptome profile of...
Type 2 innate lymphoid cells (ILC2s) promote mucosal homeostasis, yet also contribute to pathologic ...
Aneuploidy severely alters cell physiology and is widespread in cancers and other pathologies. In mo...
Purpose: To better understand the effects of glutathione (GSH)-deficiency on lens homeostasis and ca...
Purpose: Previous work has demonstrated that miR-33 is an important regulator of lipid metabolism a...
using RNA-seq we characterized gene expression changes occuring upon knockout of BAP1, ASXL1, ASXL2,...
Here, we performed RNA-Seq on mRNA isolated from primary dermal fibroblasts of human, mice and multi...
This experiment was designed to compare changes in the transcriptome of fallopian tube epithelial ce...
The nuclear RNA exosome is an essential multi-subunit complex that controls RNA homeostasis. Congen...
We show that silencing of tyrosine phosphatase PTP4A1 attenuates pro-fibrotic TGFb signaling in huma...
We report the results of RNA-Seq on fibroblasts cultivated from cancerous, colitic and normal primar...
Circulating epithelial cells (CECs) were purified using a microfluidic device from healthy donors, p...
Transcription factor (TF) networks determine cell fate in hematopoiesis. However, how TFs cooperate ...
Maintenance of muscle function requires assembly of contractile proteins into highly organized sarco...
We discovered a rare missense mutation in NR1H4 (R436H), which encodes the farnesoid X receptor (FXR...
In the adult brain, histone acetylation is associated with activity-regulated transcriptional change...
We found that the overall DNA methylation and hydroxymethylation in AG-haESCs are extremely low, and...
Surfactant deficiency, diffuse alveolar damage and respiratory failure caused by loss of Abca3 in AT...
We performed an integrated genomic analysis of NPC using a large clinical cohort of treatment-nave t...
ING1b and GADD45a are nuclear proteins involved in the regulation of cell growth, apoptosis and DNA ...
3 normal samples and 3 tumor samples were sequenced SOURCE: Baowei Jiao (jiaobaowei@mail.kiz.ac.cn) ...
To gain mechanistic insight into the role of SPIB in anoikis resistance, we assessed the transcripti...
Gene expression analysis of the knockdown of NP63 in two different human breast cancer cell lines us...
Disrupted interactions between host and intestinal bacteria are implicated in the development of col...
Background - The inability of the adult mammalian heart to regenerate following injury represents a ...
While the repressive roles of Polycomb complexes have been well-established with in vitro systems, i...
BRD4 belongs to the bromodomain and extraterminal (BET) family of epigenetic reader proteins that bi...
Danforths short tail (Sd) mice provide an excellent model for investigating the underlying etiology ...
Histone H3 lysine 4 monomethylation (H3K4me1) is an evolutionarily conserved feature of enhancer chr...
Notch1 signaling ramps up to very high levels in order to drive CD4-CD8- double-negative (DN) thymoc...
Cellular reprogramming converts differentiated cells into induced pluripotent stem cells (iPSCs). Ho...
Regulation of protein translation is a key feature of many biological processes. Global protein tran...
During normal neurodevelopment, microglia perform a range of different functions that are crucial fo...
TGF-b treatment leads to the transcriptional regulation of many genes. However, the proportion of th...
Caudal somites are generated from a pool of progenitor cells located in the tailbud region. These pr...
The CD40 gene, an important immune regulatory gene, is also expressed and functional on non-myeloid ...
With this study we aimed to characterize the changes invoked in glial progenitor cells by activation...
Astrocyte responses to neuronal injury may be beneficial or detrimental to neuronal recovery, but th...
We investigated the mechanism associated with miR-29 effects by comparing gene expression of whole p...
We investigated the genomic consequences of the depletion of the SWI/SNF subumit ARID1A, in an ovari...
N6-methyladenosine (m6A) is an essential internal RNA modification that is critical for gene expres...
Post-transcriptional regulation of cellular mRNA is essential for protein synthesis. Here we describ...
Mammalian genomes are promiscuously transcribed, yielding protein-coding and non-coding products. Ma...
Soleus muscle has the most abundant H19 expression compared to other skeletal muscle tissues. In ord...
Expression profiling by high throughput sequencing of mice overexpressing cyclin D2 compared to WT c...
Single-cell RNA sequencing (scRNA-seq) has emerged as a central genome-wide method to characterize c...
Background & Aims: The complex interactions between diet and the microbiota that influence mucosal i...
The concept that solid tumors are maintained by a productive interplay between neoplastic and non-ne...
We have demonstrated that Meteor KO cells are associated with a global transcriptional reprogramming...
We characterized the in vivo and in vitro consequences of reduced expression of Slc1a1 in mice. Hete...
Sexual dimorphism of gene expression is commonly observed in mammalian tissues, including liver. To ...