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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Fine-tuning of transcriptional responses can be critical for long-term outcomes in response to an en...
The miR-34 is a tumor-suppressor miRNA family involved in various human cancers, including breast. H...
This experiment is part of a study of differentially essential genes in H1 hPSCs grown on different ...
While transcription as regulated by histones and their post-translational modifications have been we...
Hippo-YAP signaling plays important roles in gut development and homeostasis. In this study, we use ...
The neurovascular unit, which includes neurons, glial cells, and vascular cells, plays crucial roles...
Polycomb repressive complex 2 (PRC2-EZH2) methylates histone H3 at lysine 27 (H3K27) and is required...
We performed RNA-seq with ten pieces of breast cancer (invasive ductal carcinoma; luminal B type) ti...
Colorectal cancer (CRC) remains the leading cause of cancer-related death in the world. Aspirin (ASA...
The purpose of this study was to compare the transcriptome of NIPBL patient derived iPSCs and patien...
Noonan syndrome (NS) is caused by mutations in RAS/ERK pathway genes, and is characterized by cranio...
Islet transplantation is an attractive treatment for patients with insulin-dependent diabetes mellit...
We mapped the enhancer and long non-coding transcriptional landscape during mesendoderm specificatio...
Wolffian/epididymal duct morphogenesis highly coordinates with its specialized function of providing...
Myosin IIa-deficient follicular B cells have a hyperactivated phenotype. To identify what pathways a...
Hematopoietic stem cell (HSC) function requires bone marrow vascular niches, which have been propose...
Natural killer (NK) cells are innate lymphocytes that possess features of adaptive immunity such as ...
Single-cell RNA sequencing (scRNA-seq) has emerged as a central genome-wide method to characterize c...
Most transcription factors, including nuclear receptors, are widely modeled as binding regulatory el...
The homeotic (Hox) genes are highly conserved in metazoans, where they are required for various proc...
Rhabdomyosarcoma (RMS) is an aggressive and difficult to treat cancer characterized by a muscle-like...
Understanding the principles of endogenous chromatin structure has key implications for epigenetic t...
The human aged hematopoietic system is prone to dysfunction and clonal selection. Aged hematopoietic...
Targeting of general coactivators, such as BRD4, is an emerging strategy to interfere with oncogenic...
Purpose: Cortical thymic epithelial cells (cTECs) contain a unique type of proteasomes, thymoproteas...
Expression profiling by RNA-seq SOURCE: stefano campaner (stefano.campaner@iit.it) - Cancer Biology ...
In the present study, we identify transcriptional mechanisms associated with corticospinal regenerat...
We report RNA-Seq data file from 3T3-L1 adipocytes following overexpression and knock-down of Dnmt3a...
Mesenchymal cells were isolated from day 5 dorsal skin wound beds of 7-weeks old and >24-months old ...
Post-translational modifications of histones are well-established epigenetic modifications that play...
DLX4 is a member of DLX family of mammalian homeobox genes and cis linked sister gene of Dlx3. Misex...
We used RNA sequencing to characterize gene expression of dendritic cells from mouse lymph node that...
Purpose: Compare the transciptome between lung myofibroblasts that contituatively express Fra-2 to c...
RNA sequencing on LNCaP cells was carried out to study how tunicamycin-induced gene expression is af...
DHX36 is a ATP-dependent, 3-5 RNA helicase of the DEAH family. Previous publications reported this h...
RNA sequencing was performed to investigate ionizing radiation-dependent transcriptional change in h...
BOFS is a rare congenital syndrome that arises due to defects during neural crest (NC) development a...
We delineate the immunobiology during MYC oncogene-driven lymphomagenesis by RNA sequencing analysis...
MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression post-transcriptionally. m...
The role of chromatin-mediated regulation in cell-fate specification during mammalian development is...
Neural stem cell activity in the ventricular-subventricular zone (V-SVZ) decreases with aging, thoug...
Dysregulation of the kynurenine (Kyn) pathway has been associated with the progression of Huntington...
Human pluripotent stem cells (hPSCs) provide both powerful models for studying cellular differentiat...
To screen for altered gene expression during osteoclastogenesis, BMM cells treated with RANKL or RA...
RNA-seq samples used to support a study in to the understanding of antioxidant targeting in adrenoco...
Purpose: To create a radiogenomic map linking computed tomographic (CT) image features and gene exp...
We profiled gene expression of mouse chondrocytes from embryonic and adult samples. SOURCE: Denis,A,...
Direct lineage conversion offers a new strategy for tissue regeneration and disease modeling. Despit...
In order to identify and characterize novel human gene expression responses to glucocorticoids, we e...
We identified BRD4 as an epigenetic regulator of the prostate lineage specific gene HOXB13 during ...
This dataset consists of RNA-sequencing of isolated mouse intestinal epithelial cells. Intestinal ep...
Mechanisms regulating mammalian meiotic progression are poorly understood. Here we identify mouse YT...
The ability to predict transcription factors based on sequence information in regulatory elements is...
In mammals during the early postnatal period the environment plays a critical role in promoting the ...
To evaluate the impact of ASO-mediated depletion of NMD factor Upf1 and Upf3b on the normal transcri...
The experiment aims to distinguish the transcriptome influenced by the extinction of the lncRNA, aft...
Purpose: We treated melanoma cell lines with IFNG to assess which ones would be resistant or respon...
The mammary epithelia are mainly composed of two distinct lineages, the basal and luminal cells. Due...
Polycomb repressive complexes (PRC) 1 and 2 are essential chromatin regulators of cell identity. PRC...
How gender influences the molecular properties of pluripotent stem cells (PSCs) remains incompletely...
Purpose:The goals of this study are using next generation sequencing to identify differentially expr...
Ten-Eleven-translocation (Tet2) encodes an epigenetic modifier enzyme and is mutated somatically dur...
The cellular mechanism(s) linking macrophages to norepinephrine (NE)-mediated regulation of thermoge...
Purpose: Next-generation sequencing (NGS) has revolutionized systems-based analysis of cellular func...
Aging is associated with fundamental changes in pancreatic -cell physiology; yet, the mechanisms tha...
We use RNA-seq on mRNA to identify genes that are differential expressed in human cells following de...
Exosomes are small extracellular vesicles of around 100nm of diameter produced by most cell types. T...
RNA-seq of mRNA from five stimulation time point (LipidA, 100ng/ml) of bone marrow-derived macrophag...
We performed a systematic analysis of the coding and non-coding transcriptomes of human macrophages ...
The immune system faces a task that approximates cognition in its complexity as it processes a multi...
We aimed at identifying a common transcriptional response of neurons to acute injury by conducting a...
Gastro-intestinal helminth infections trigger the release of interleukin-33 (IL-33), which induces t...
Total RNA sequenceing method was used to compare the differential expression of genes in A2780, CAOV...
Mutations in the RNA splicing complex member SRSF2 are found frequently in myelodysplastic syndrome ...
Macrophages are a major target for human immunodeficiency virus type 1 (HIV-1) infection. However, m...
In order to decipher the mechanisms of DM1 disease, we generated new DM1 mouse model and found the k...
Obesity is a risk factor for Osteoarthritis (OA), the greatest cause of disability in the US. The i...
We have established a vascular organoid culture system with self-assembled endothelial networks that...
Very little is known about splicing and its regulation in germ cells, particularly during meiosis. T...
Inhibiting tafazzin a cardiolipin remodeling enzyme reduces stemness of AML by modulating the level ...
ChIP-exo of Flag-SETMAR in U2OS-SMF cell line, RNA-seq in duplicates for the U2OS control cell line,...
To analyse and understand the differentially expressed genes following treatment with synthetic andr...
Small molecule targeted recruitment of nucleases to RNA is a powerful method to affect RNA biology. ...
The methylcytosine dioxygenase Tet3 is highly expressed as a specific isoform in oocytes and zygotes...
We report systematical profiling of translation efficiency and mRNA stability dependent on the dynam...
Purpose: The goals of this study is to examine if feeding NOD mice with diets supplemented with SCF...
Here, we show that CR enhances regenerative capacity of the intestinal epithelium as a result of inc...
YAP and TAZ play oncogenic roles in various organs, but the role of YAP/TAZ activation in gastric ca...
Using HIV-1 SortSeq, we identified HIV-1-infected cells containing inducible HIV-1 for RNAseq from r...
MLLT3 preserves the FL-HSPC gene expression signature in culture SOURCE: Vincenzo Calvanese (vincalv...
RNA sequencing was performed on HCT116 and HKE3 colorectal cancer cell lines before stimulation and ...
Comparative transcriptomic analysis of A549 cell after overexpression of miRNA-30e-5p revealed that ...
Vertical sleeve gastrectomy (VSG) produces sustainable weight loss, remission of type 2 diabetes (T2...
Alternative splicing (AS) represents a powerful resource to amplify the coding potential of eukaryot...
FLT3ITD are common mutations in Acute Myeloid Leukemia (AML) and carry a particularly bad prognosis....
Surgery and cisplatin-based treatment of hepatoblastoma (HB) currently guarantee the survival of 70-...
Transcriptome profiling (mRNA-seq) of melanoma cells overexpressing NICD SOURCE: Vijayasaradhi Setal...
Methionine concentration in diet influences the growth rate of metastatic cells in vivo SOURCE: Kyle...
Fibroblasts can be directly reprogrammed toward a cardiac fate by introducing cardiogenic transcript...
The aim of the project was to characterize the transcriptional landscape of human HUVEC cells expose...