Explore curated data sets and assays
Pluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for access
Sequencing-based assays page 60
Store large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
GSE99598: Transcriptome analysis of Bcl11b-deficient CD4+ T-cells during Th2 immune response
Nave CD4+ T-helper cells differentiate into Th2 effector cells during asthma and helminth (worm) inf...
GSE155775: Human Keratinocyte Response to Superantigens
Purpose: The goal of this study was to determine what genes and canonical pathways are altered by ex...
GSE107942: Lipoxins Regulate the Egr-1 Network and Reverse Diabetic Kidney Disease
The failure of spontaneous resolution underlies chronic inflammatory conditions including microvascu...
GSE106973: Single cell RNA sequencing of murine basophil/mast cell progenitors and granulocyte/monocyte progenitors
We have performed single cell RNA sequencing of murine bone marrow progenitors to study the early di...
GSE103521: RNA-seq data for lineage negative, Sca1 positive, and cKit positive hematopoietic stem/progenitor cells from H3.3K36M, H3.3K9M, or rtTA control mice
We analyzed gene expression patterns in LKS cells using RNA-seq after one week of mutant histone ind...
GSE121559: RNA-Seq of human induced pluripotent stem cell-derived cardiomyocytes from a cardiomyopathy patient and familial control
RNA-Seq of human induced pluripotent stem cell-derived cardiomyocytes from a cardiomyopathy patient ...
GSE109214: SCNT embryos are defective for H3K27me3 imprinting [RNA-seq]
Animal cloning can be achieved through somatic cell nuclear transfer (SCNT), yet the success rate re...
GSE58993: RNA-seq of 8hr LPS-stimulated bone marrow-derived macrophages from wild type, Ch25h-deficient, and LXRab knockout mice
25-hydroxycholesterol has been demonstrated to regulate SREBP processing, yet Ch25h-deficient mice h...
GSE106188: Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenaline
The arcuate nucleus of the hypothalamus (ARH) is one key structure controlling energy homeostasis. W...
GSE104181: CNS-draining lymphatics play a key role in age-dependent cognitive decline and Alzheimers disease pathology [1 of 3]
Aging is a major risk factor for many neurological pathologies, including Alzheimers disease (AD). H...
GSE107958: RNA sequencing of a Spinocerebellar ataxia type 3 (SCA3) mouse model containing the full human ATXN3 gene with a repeat expansion of 75-80 CAGs I
We have performed RNA sequencing analysis of brain tissue and blood from the MJD84.2 mouse model for...
GSE107280: Gene expression profiling by RNA-seq in hTert-HME1 cell line treated with control or BRCA2 siRNAs and grown with or without EGF (epithelial growth factor) II
hTert-HME1 cells were treated with control or BRCA2 siRNAs and then allowed to recover, then grown i...
GSE108243: RNA-seq profiling of mouse embyonic fibroblasts treated with the Myst inhibitor WM-8014
Acetylation of histones by lysine acetyltransferases (KATs) is essential for transcriptional regulat...
GSE107692: siRNA-mediated silencing of ORAI3 in MDA-MB-468 breast cancer cells exposed to hypoxia
Analysis of the effect of siRNA-mediated silencing of ORAI3 in MDA-MB-468 basal-like breast cancer c...
GSE107965: Transcriptome analysis of human embryonic stem cells (hESCs) and human fibroblasts upon rapamycin
Rapamycin inhibits mTORC1 complex in a variety of cells. We demonstrated that hESCs are more sensiti...
GSE104320: PP1-NIPP1 wild type and mutant overexpression in Flip-In T-Rex Hela cells
RNAi-seq of stable Flp-In T-Rex Hela cells that inducibly expressed PP1-NIPP1 and mutants. SOURCE: W...
GSE109633: Effects of Hif1a mutation and maternal diabetes on the offspring heart
We analysed the combined effects of exposure to maternal diabetes and disrupted HIF-1 signaling on ...
GSE109488: Survey of Human Fetal Kidney Development Through Single Cell RNA Sequencing Analysis
Human kidney is a major metabolic organ, which plays a crucial role in regulating homeostasis of hum...
GSE98142: Differential impact of Dicer deficiency on microglia of the developing and adult brain (Bulk RNA-Seq)
Microglia seed the embryonic neuro-epithelium, expand and actively sculpt neuronal circuits in the d...
GSE129316: Generation of induced keratinocyte stem cells from human urine cells by defined transcription factors
Analysis of induced keratinocyte stem cells from male/female urine cells (MiKSC/FiKSC) by defined tr...
GSE106928: A lysosome-plasma membrane-sphingolipid axis linking lysosomal storage to cell growth arrest
We used human fibroblasts loaded with sucrose as a simple model of lysosomal accumulation, and we ve...
GSE98506: Analysis of LPS-stimulated WT and Tnip2[D310N] bone marrow-derived macrophages
This experiment was conducted to analyse the effect of mutating the ubiquitin binding function [D310...
GSE102485: Transcriptome Profile and Marker Gene Discovery from Patients with Proliferative Diabetic Retinopathy by RNA-seq
Proliferative diabetic retinopathy (PDR) is the advanced stage of diabetic retinopathy (DR), couplin...
GSE106107: RNA-Seq of CD8+ T cells expressing different levels of Runx3 in a cell culture model of CTL differentiation
Tissue-resident memory CD8+ T cells (Trm) are positioned at common sites of pathogen exposure where ...
GSE109280: Boosting ATM activity alleviates ageing and extends lifespan in a mouse model of progeria.
Protein deacetylase SIRT6 and protein kinase ATM both decline during aging, which are of importance...
GSE100460: Gas41 links histone acetylation to H2A.Z deposition and stem cell identity maintenance
The histone variant H2A.Z is essential for maintaining the identity of embryonic stem cell (ESC) by ...
GSE106711: Epigenetic regulation by BAF (mSWI/SNF) complexes limits neural stem cell proliferation by suppressing Wnt signaling in late cortical neurogenesis
We have analyzed changes in gene expression, histone 3 lysine 4 dimethyl (H3K4me2) and histone 3 lys...
GSE106663: The BLUEPRINT Murine Lymphocyte Epigenome Reference Resource [scRNA-Seq]
This data release is part of the EU BLUEPRINT reference epignome project (http://www.blueprint-epige...
GSE126861: KDM2 proteins constrain transcription from CpG island gene promoters independently of their histone demethylase activity [RNA-seq]
CpG islands (CGI) are associated with the majority of mammalian gene promoters and function to recru...
GSE106688: Dynamic reorganization of nuclear architecture during human cardiogenesis [RNA-seq]
While chromosomal architecture varies among cell types, little is known about how this organization ...
GSE105086: The age of the hematopoietic microenvironment specifies lineage in MLL-rearranged leukemia [Ccl5]
The defining characteristics of leukemia, such as lineage and genetics, are associated with a typica...
GSE107004: Transcriptomic analysis of adult mouse hippocampal tissue in control and MeCP2 knockdown conditions
The overall goal of this study was to clarify the role of MeCP2 in adult cognition.; As one of the m...
GSE109630: Health-relevant phenotypes in the offspring of mice given CAR activators prior to pregnancy
The hepatic induction in response to drugs and environmental chemicals affects drug therapies and en...
GSE98513: Suppression of asthmatic phenotype and altered lipid metabolism in mice lacking zona pellucida binding protein 2
The human chromosomal region 17q12-q21 is associated with childhood asthma. It harbors 5 protein-co...
GSE104264: Transcriptome determinants of lung seeding by mammary tumor cells
Metastasis accounts for most of cancer-related deaths. Paracrine signaling between tumor cells and t...
GSE107277: LncRNA RVRL1 restricts rabies virus infection by disrupting PRC2 complex [RNA-seq]
Rabies is an ancient infectious disease but still lacking efficient therapeutic approach despite of ...
GSE138001: Cortical RORb is required for layer 4 transcriptional identity and barrel integrity
RNA-seq and ATAC-seq from layer 4 cortical neurons expressing RORb-gfp or GFP in an RORb KO. SOURCE:...
GSE98496: mRNA-seq data from murine colon adenomas and non-adenoma tissues
We report that colon adenomas from ApcMin/+ mice not only exhibit similarities in gene expression pr...
GSE106292: Gene expression profiling of human musculoskeletal tissue samples
We profiled gene expression of purified cell types isolated from 5 musculoskeletal tissues: tendon, ...
GSE112483: Celll type specific gene expression from healthy human lung tissue infected with mycobacterium tuberculosis (innate).
We have investigated the initial responses in human lung tissue explants to Mtb infection, focusing ...
GSE106767: Hair follicle stem cells sense niche integrity and recruit immune cells to contain barrier breaches
We demonstrated that hair follicle stem cells (HFSCs) are able to sense the integrity of their epith...
GSE105944: Dynamic remodeling of mRNA splicing and translation programs drives hepatocyte proliferation during liver regeneration
During liver regeneration, most new hepatocytes arise from pre-existing ones; yet, the underlying me...
GSE98755: FBXL19 transcriptionally primes promoters of developmental genes via CDK8-Mediator recruitment [RNA-seq]
Regulatory elements called CpG islands (CGIs) are associated with the majority of mammalian gene pro...
GSE98257: R-Spondin chromosome rearrangements drive Wnt-dependent tumor initiation and maintenance in the intestine
Defining the genetic drivers of cancer progression is key to understanding disease biology and devel...
GSE113752: CDK6 antagonizes p53-induced responses during tumorigenesis
CDK6 induces a complex transcriptional program to block p53 in hematopoietic cells. CDK6 binds to t...
GSE107288: RNA-seq data of effects of DCPS inhibition in mouse AML cells (CALM/AF10) and in normal GMP cells. Overall mRNA profiles of CALM/AF10 (#1/#2) and MLL/AF9 (#1/#2).
Purpose: The goals of this study are to assess the possibility whether DCPS inhibition would impair ...
GSE106926: The transcription factor BATF3 regulates the differentiation of TH9 cells and TH9-driven mucosal pathologies
T helper 9 (TH9) cells are important for the development of inflammatory and allergic diseases. The ...
GSE106975: KAP1 targets actively transcribed genomic loci to exert pleomorphic effects on RNA Polymerase II- and III-mediated expression [RNA-Seq, small RNA-Seq]
KAP1 (KRAB-associated protein 1) is best known as a co-repressor responsible for inducing heterochro...
GSE106716: SYK activity modulates the EGFR-dependent transcriptome
Background: Among all gynecologic malignancies, epithelial ovarian cancer has the highest case-to-fa...
GSE104285: RNA sequencing of WT and ERRAd-/- brown adipose tissue treated with CL316,243
Adrenergic stimulation of brown adipose tissue (BAT) activates thermogenesis, by uncoupling oxidativ...
GSE98262: The TNF receptor super family - NF-B axis is critical to maintain effector regulatory T cells in lymphoid and non-lymphoid tissues [RNA-seq]
After exiting the thymus, Foxp3+ regulatory T (Treg) cells undergo further differentiation in the pe...
GSE109648: Hemogenic Endothelium transcriptome along the timeline of hESC differentiation
The differentiation of human embryonic stem cells to hematopoietic lineages initiates with the speci...
GSE104232: NFIA enables the rapid derivation of functional, human astrocytes from pluripotent stem cells by modulating G1 cell cycle length
The development of the central nervous system (CNS) depends on the orchestrated generation of neuron...
GSE107685: Gene expression changes in human iPSC-derived cardiomyocytes after X-ray irradiation
Within the present study we evaluated hiPSC-CMs as a possible methodological extension for the asses...
GSE118184: Comparative analysis of kidney organoid and adult human kidney single cell and single nucleus transcriptomes
We analyzed single cell transcriptomes over 80,000 cells isolated from 65 organoids differentiated f...
GSE149205: REQUIREMENT FOR PKC EPSILON IN KRAS-DRIVEN LUNG TUMORIGENESIS
Non-small cell lung cancer (NSCLC), the most frequent subtype of lung cancer, remains a highly letha...
GSE109999: Single cell profiling of mouse blood cells using CEL-seq2
Gene expression in mouse blood cells from sorted via FACS analysis into a 384-well plate were profil...
GSE104295: Analysis of gene expression in SKOV3 ovarian cancer cells after knockdown of the long non-coding RNA DNM3OS
RNA-sequencing was performed to gain insight into the mechanism responsible for the mesenchymal-to-e...
GSE122274: Bacterial sepsis triggers an antiviral response that causes translation shutdown
In response to viral pathogens, the host upregulates antiviral genes that suppress translation of vi...
GSE106803: The role of SIRT1 deacetylase in neuromuscular aging and amyotrophic lateral sclerosis
SIRT1 deacetylase functions in a variety of cells and tissues to mitigate age- and disease-induced d...
GSE108348: Transcriptome variations across species, organs and developmental stages
We sequenced polyA-selected transcriptomes from three species (mouse, rat and chicken), four organs ...
GSE104496: RNA-seq total KO experiments for "Chronic repression by MAF1 supports futile RNA cycling as a mechanism for obesity resistance"
To examine the effect of MAF1 on the RNA polymerase II transcriptome, RNA-seq was performed on sampl...
GSE107339: Transcriptome Effects of the knockout of Intraflagellar Transport 88 gene in mice Mitral leaflets
The gene Ift88 is a gene critical for primary cilium biogenesis, the objective this study was to det...
GSE106772: RNA m6A-Ythdf1 in dendritic cells triggers anti-tumor immunity (RNA-seq and RIP-seq in in GMDCs)
Emerging evidence emphasizes the important role of tumor neoantigen in generating the spontaneous an...
GSE105044: RNA-seq of LCMV GP33-specific CD8 TCR transgenic cells (P14) primed at the onset versus in the midst of persistent LCMV-Clone 13 viral infection
Altered CD8 T cell differentiation and functional exhaustion prevent control of chronic virus infect...
GSE110243: Gene-specific mechanisms dictate glucocorticoid receptor-mediated repression of inflammatory response genes in macrophages [RNA-seq]
The Glucocorticoid Receptor (GR) potently represses macrophage-elicited inflammation, however, the u...
GSE110867: Identification and validation of GPD1 as an essential cancer stem cell specific target in glioblastoma (RNA-seq: NSC vs BTSC)
Cancer stem cells (CSCs) are attractive targets for cancer therapy, however, little is known about h...
GSE107413: Expression levels of genes of LCMV.GP66-77 specific CD4 T cells isolated from bone marrow (BM) and spleen, 3 days after antigenic re-challenge
We performed RNA-Seq and compared expression levels of genes of reactivated LCMV.GP66-77 specific CD...
GSE104507: Type I interferon signaling attenuates regulatory T cell function in viral infection and in the tumor microenvironment
Regulatory T cells (Tregs) play a cardinal role in the immune system by suppressing detrimental auto...
GSE99765: Genomic plasticity in the hippocampus
We examined the effects of technial and behavioral manipulation on gene expression of in the CA1, CA...
GSE110278: Induction of human regulatory innate lymphoid cells from group 2 innate lymphoid cells by retinoic acid
We aimed to determine the characteristic of IL-10-producing ILCs induced from ILC2s by RA. We found ...
GSE119578: RNA sequencing of Asthmatic Human Airway Smooth Muscle Cells I
The goal of the was to evaluate the mRNA expression profile of non-asthmatic and asthmatic airway sm...
GSE111573: The absence of H2A.Z does not affect both basal and activated transcription in post-mitotic muscle cells in vivo [RNA-Seq - muscle]
The histone variant H2A.Z is an essential protein that exists in two very close isoforms, H2A.Z-1 an...
GSE110268 (mouse): Upregulation of FOXD1 by YAP alleviates senescence and osteoarthritis
Cell senescence is a driver of various aging-associated disorders including osteoarthritis. Here, we...
GSE99068 (mouse): IL-6/Stat3-Dependent Induction of Distinct, Obesity-Associated Natural Killer Cells Deteriorates Energy and Glucose Homeostasis
Natural killer (NK) cells contribute to the development of obesity-associated insulin resistance. We...
GSE98491: Phenotypic Correction of Oligodendrocytes by Concurrent Direct Reprogramming and Gene Replacement of Fibroblasts
Transcription factor-mediated direct reprogramming technologies that can convert one differentiated ...
GSE110882: Bcl11b defines pro-T identity by site-specific cofactor recruitment and by repressing Id2 and Zbtb16 [RNA-seq]
Multipotent progenitors confirm their T-lineage identity at the DN2a to DN2b pro-T cell transition, ...
GSE112431: Transcriptomic analysis of control lung alveolar type 2 cells and constitutively active-BMPR1a overexpressing alveolar type 2 cells
The Bone Morphogenetic Protein (BMP) signaling pathway functions in lung development and the regener...
GSE110912: Effect of TGFb1 treatment and WISP1 overexpression on 4T1 breast cancer cells
This study set out to identify TGFb1 transcriptional targets in breast cancer cells. 4T1 breast canc...
GSE107010: TRPS1 shapes YAP/TEAD-dependent transcription in breast cancer cells [RNA-seq]
We report the gene expression profiles of TRPS-depleted and YAP 5SA overexpressing breast cancer cel...
GSE99774: Pancreatic gene expression during recovery after pancreatitis reveals unique transcriptome profiles
Histological resolution of the murine pancreas occurs within one week after injury. Whether histolog...
GSE117549: Crebbp loss drives small cell lung cancer and increases sensitivity to HDAC inhibition [pituitary tumor]
This study assessed tumor suppressor roles of CREBBP in SCLC and other neuroendocrine tumors. Geneti...
GSE104608: Epigenetic Inactivation of Cysteine Dioxygenase Type 1 Contributes to ROS-dependent Progression of Colorectal Cancer
We performed a comprehensive investigation to understand the clinical and biologic significance of C...
GSE110914: Abnormal neutrophil signature in the blood and pancreas of pre-symptomatic and symptomatic type 1 diabetes
Analysis of neutrophils purified from peripheral blood of patients with symptomatic and pre-symptoma...
GSE106857: The role of microglia in maturation of adult-born neurons
Microglia depletion significantly lowered spine density in young (developing) but not mature adult-b...
GSE99093: RNA-Sequencing of Regenerating Lacrimal Glands
The purpose of the present studies was to use CyTOF and RNA-Seq technologies to identify cells and g...
GSE107761: Single-cell transcriptome profiling during the in vitro differentiation of mouse ESCs (mESCs) into epiblast-like cells (EpiLCs).
We performed single-cell RNA sequencing (RNA-seq) during the in vitro transition of mouse ESCs (mESC...
GSE108349: Derivation of kidney organoids from human pluripotent stem cells [RNA-Seq: Data Set 1]
We have developed a robust methodology for the derivation of kidney organoids from human pluripotent...
GSE117657: Effect of NOX2 (CYBB) knock out on the transcriptome of leukemia stem cells isolated from NUP98/HOXA9+BCR/ABL murine syngeneic leukemia model
To investigate the function of NOX2 (CYBB) in leukemia stem cells, we created leukemia by tranformin...
GSE114037: Targeted sequencing based maternal whole blood expression changes with gestational age and labor in normal pregnancy
Maternal plasama colected longitudinally were profiled using targeted sequencing (DriverMap) (https:...
GSE120276: The Transcriptional Regulator SnoN Promotes the Proliferation of Cerebellar Granule Neuron Precursors in the Postnatal Mouse Brain
Control of neuronal precursor cell proliferation is essential for normal brain development, and dere...
GSE110504: SOX21 ensures rostral forebrain identity by suppression of WNT8B during neural regionalization of human embryonic stem cells
Generation of brain region-specific progenitors from human embryonic stem cells (hESCs) is critical ...
GSE110866: Identification and validation of GPD1 as an essential cancer stem cell specific target in glioblastoma (Ribosome profiling)
Cancer stem cells (CSCs) are attractive targets for cancer therapy, however, little is known about h...
GSE111633: Global analysis of gene expression changes following LINE1 inhibition [III]
Transposable elements make up nearly half of mammalian genomes, yet are generally described as junk ...
GSE106339: Whole ovaries RNA sequencing; WT and ghrelin o-acyltransferase (GOAT) knockout mice
Ghrelin, an orexigenic gut-derived peptide, is gaining increasing attention due to its multifaceted ...
GSE107981 (human): Effector and regulatory T cells roll at high shear stress by inducible tether and sling formation
The adaptive immune response involves T cell differentiation and migration to sites of inflammation...
GSE106396: Control of RORgt+ regulatory T cell differentiation and intestinal immune homeostasis is dependent on the transcription factor c-Maf
Foxp3+ regulatory T (Treg) cells are essential for immunological tolerance and homeostasis. In perip...
GSE101112: Whole transcriptome analysis of brain hippocampal tissue from SAMP8 mice and rat primary neurons treated with the Alzheimer's disease drug candidates CMS121 and J147
Alzheimer's disease (AD) drug discovery has rarely been addressed in the context of aging even thoug...
GSE98295: miR-140 mutation and skeletal dysplasia [RNA-seq]
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression. Heterozygous loss-of-func...
GSE107776: Damage-associated molecular patterns induce macrophage polarization toward an M1 pro-inflammatory phenotype
Dying cells release Damage-Associated Molecular Patterns (DAMPs) that can initiate and perpetuate st...