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Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Early onset preeclampsia (EOPE) affects about 0.4% of pregnancies and is characterized by impaired t...
Regulator of G protein signaling z1 (RGSz1), a member of the RGS family of proteins, is present in s...
Aging is associated with functional decline of hematopoietic stem cells (HSC) as well as an increase...
We assessed the feasibility of transplanting a sheet of retinal pigment epithelial (RPE) cells diffe...
We have builded a network including mRNA, miRNA, piRNA, lncRNA and circRNA after exposure to MC-LR f...
Endocrine therapy resistance invariably develops in estrogen receptor positive (ER+) breast cancer, ...
The molecular chaperons FK506-binding proteins (Fkbps) comprise one of three families of peptidyl pr...
In comparison with exosomal mRNAs in CSF from four patients with amyotrophic lateral sclerosis, 543 ...
Identification of Nanog targets by transcriptomic changes of Nanog induction and depletion, identifi...
Purpose: we used next generation sequencing to analyze gene expression profiles of lung and spleen t...
Using RNA-seq we characterized gene expression changes occuring upon knockout of EZH2, EZH1, EZH1+EZ...
Analyses of IL-1b-induced transcriptome in various skin-relevant cell types (keratinocytes, dermal f...
A panel of human fibroblasts derived from patient samples (vulval, oral, cervical and breast carcino...
The adoptive transfer of cancer-specific T cells in combination with high dose interleukin-2 (IL-2) ...
Purpose: Transcriptomic analysis of skin innate lymphoid cells; Methods: Innate lymphoid cells were ...
iPSC derived dopaminergic neuron cultures sequenced from different patient lines. SOURCE: Samuel,A,S...
We report NRF2-dependent changes in the transcriptome of A549, H460 and H2023 cell lines. SOURCE: Ho...
Vascular endothelial cells (ECs) derived from the central nervous system (CNS) variably lose their u...
By m6A-seq, we examined the m6A pattern on Xist, which immediately after the A-repeat region. The ce...
T cell receptor (TCR) stimulation of nave CD8+ T cells initiates reprogramming of cis-regulatory lan...
Follicular helper T (Tfh) cells are essential for generating protective humoral immunity. To date, m...
We utilized RNA-sequencing strategy to explore the characterstics of gene expression profile of LSEC...
Virus and host factors contribute to cell-to-cell variation in viral infection and determine the out...
To evaluate the potential role of Hes1 in regulation of type I IFNs and the downstream ISGs expressi...
Dravet syndrome is a severe, early-onset epileptic encephalopathy frequently resulting from de novo ...
G-quadruplexes (G4) are secondary nucleic acid structures that have been associated with genomic ins...
To identify p53-regulated lncRNAs responsive to DNA damage in human hepatocellular carcinoma (HCC) c...
To identify transcription factors critically involved in the Tfh cell transcriptional network, antig...
To analyze transcriptional expression profile in CTC and tumor cells SOURCE: Yi Fan (Yi.Fan@uphs.upe...
We show that mesenchymal CSC-like cells express an embryonic stem cell signature that is mutant p53 ...
Description: We find multiple evidence that mitochondria are directly and indirectly involved in the...
the gene expression profiles of 3 cultured MEFs from NGLY1 knockout mice was compared to 3 cultured ...
A direct comparison of NAC and EEC allergen challenges revealed differences in the kinetics and magn...
Gene expression analysis of HeLa cells exposed to hypoxia (1% Oxygen), treated with a PHD inhibitor ...
Long noncoding RNAs (lncRNAs) have emerged as important components of gene regulatory network in emb...
In mammals, most immature oocytes remain dormant in the primordial follicles in order to ensure the ...
To understand the molecular signatures of Dek over-expressed quiescent muscle stem cells in vivo, we...
The innate immune cell compartment is highly diverse in the healthy central nervous system (CNS) inc...
The transcriptional profile of A673 parental, and SP-2509 drug resistant washout cells (4 and 6 mon...
Epigenetic modifications operate in concert to maintain cell identity, yet how these interconnecte...
The transcriptional profile of A673 parental and SP-2509 Drug resistant cells treated with DMSO and ...
Prdm12, a novel key regulator of the Nerve Growth Factor-TrkA signaling pathway, is required for noc...
Induction of hepatocyte senescence is known to inhibit hepatocellular carcinoma (HCC). Until now, it...
To identify the AR-V7 target genes in human prostate cancer, two cell lines (LNCaP, LNCaP95) were s...
Analysis of adult and embryonci stem cells depleted for DDX6. Results provide insight into the regul...
H3.3 knock-in mice serve as a useful experimental model to study epigenome regulation in development...
Excessive fructose consumption causes fatty liver disease and steatohepatitis, conditions that eleva...
Gene expression profile of AML generated via 3 related transgenes is compared. SOURCE: Peter Aplan C...
The spatial organization of chromosomes influences many nuclear processes including gene expression....
Alteration in RNA editing has been connected to tumor progression and many other important human dis...
Pioneer transcription factors (PTF) can recognize their binding sites on nucleosomal DNA and trigger...
Human dendritic cells were exposed to LPS, in the absence and presence of adenosine receptor 3 inhib...
Using lineage-tracing in a well-established psoriasis-like mouse model with inducible epidermal dele...
Despite the key role that antibodies play in protection against malaria, the cellular processes modu...
We report the application of next-generation sequencing (NGS) to analysis the gene expression profil...
Shank3 is a core excitatory postsynaptic protein expressed in multiple brain regions including the m...
tRNAs are subject to numerous modifications including methylation. Mutations in the human N7-methylg...
Adolescent stress can impact health and well-being not only during adulthood of the exposed individu...
We generated RNA-seq data to measure transcriptional profiles of twenty hPSC-derived NSC populations...
Here, we use a microfluidics-based approach to prepare single-cell RNA-Seq libraries from 164 primar...
To induce tumorigenesis in the esophagus, 100 mg/mL of the water-soluble carcinogen 4NQO (Sigma-Aldr...
Male mammals must simultaneously produce prodigious numbers of sperm and maintain an adequate reserv...
Purpose: To identify TP63 expression regulated pathways in HNSCC; Methods: A recombinant lentivirus ...
While protein arginine methyltransferases (PRMTs) and PRMT-catalyzed protein methylation have been w...
The purpose of this study was to compare the transcriptome of NIPBL patient derived Hematopoietic pr...
Breast tumors are characterized by inherent heterogeneity but the evolving cellular organization of ...
Early mammalian development is accompanied by a profound global remodeling of chromatin-based regula...
The rapid improvements in single cell sequencing technologies and analyses methods afford greater sc...
Mouse embryonic stem cells (ESCs) sporadically express preimplantation two-cell-stage (2C) transcrip...
We characterized the effect of GSK-LSD1 treatment on gene expression for both wt SET-2 and drug-resi...
Purpose: PM2.5 can impact mouse TH17 cell differentitation. To Investigator the genes altered by PM2...
We have performed modular analyses to decipher the global transcriptional response and capture a bre...
During immune ontogeny the thymus is colonized by distinct waves of hematopoietic stem cells that gi...
Purpose: to analyze gene expression in THZ531 treated liver cancer cells. Methods: Hep3B and Huh7 ce...
Single cell RNAseq of Old (19 month) and Young (3 month) mouse brain endothelial cells isolated from...
The CCCTC-binding factor (CTCF) is a versatile transcriptional regulator required for embryogenesis,...
CD4+T cells are differentiated into Th1, Th2, Th17 and Treg cells after Antigen presentation by othe...
Gene expression networks are tightly regulated by transcription factors (TF) and their targeted regu...
Neural stem cells (NSCs) are valuable for both basic research and clinical application. We previousl...
The overall goal of this study was to characterize the activity and mechanism(s) of action of the pa...
In this article, Jose Polo and colleagues molecularly compare existing microglia differentiation met...
Rett syndrome is a severe neurodevelopmental condition that rsults primarily from mutations in the M...
We identified the first Spt5-Pol II inhibitors (SPIs). SPIs faithfully reproduced Spt5 knockdown eff...
Quiescent splenic B cells purified from Cg1-cre Prmt5F/F cells and Cg1-cre control mice. Resting B c...
RNA-seq profiles of patient-derived primary CLL cells when co-cultured with bone marrow derived mese...
The crosstalk between the microbiota and the immune system plays a fundamental role in the control o...
CD4+ T cells play a key role in the adaptive immune system. Their subset, Th17 cells contribute to p...
Background Ageing is characterised by loss of function of the adaptive immune system, but the under...
Purpose: Tumor-specific antigens (TSAs) represent ideal targets for cancer immunotherapy, but very f...
Pleomorphic adenoma gene 1 (PLAG1) encodes a transcription factor involved in cancer and growth. We ...
Integrin 31 in hair bulge population affects the tumor formation following DMBA/TPA carcinogenesis p...
Transforming growth factorbeta (TGF1) plays an important regulatory role in the progression of chron...
Bisphenol A (BPA), known as an endocrine disruptor, is widely used in the world. BPA is reported to ...
Although mechanisms of acquired resistance of EGFR mutant non-small cell lung cancers to EGFR inhibi...
Treatment with IL-1b or TNFa enhance the proliferation of alveolar type 2 cells in organoid culture....
The human pluripotent stem cells cultured on Low-adhesion substrates formed two morphologically diff...
We applied previously established in silico whole-embryo body (WB)-subtraction-based approach to id...
Pancreas tissue derived from mice with intraperitoneal injection of saline, cerulein or polyI:C plus...
RNA-sequencing analysis was carried out on ascitic fluid-isolated mesothelial cells from ovarian can...
Gut resident IL10+CX3CR1hi macrophages drive development of mucosal tertiary lymphoid structures tha...