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Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
Neurogenesis entails a highly orchestrated process from pluripotent to neural cell fates including p...
The skin is the human bodys largest organ and is in contact with a diverse community of microorganis...
We describe here a novel role for CHD1 in regulating the osteoblast cell fate by studying the effect...
Purpose: To investigate the impact of oncogenic Notch on the 3D genome organization of cancer cells....
The CBF-MYH11 fusion generated by inv(16) aberration is proposed to block normal myeloid differentia...
Accumulation of subcutaneous white adipose tissue (WAT) is associated with increased insulin sensiti...
In mammalian embryos, the stepwise generation of hematopoietic stem cells (HSCs) from endothelial pr...
Pregnant mice were infected with Heligmosomoides bakeri nematode on gestation day 7, 12 and 17 and o...
We applied RNA-Seq to analyze the effects of silencing of Thoc2 or Thoc5, two components of the THO ...
To study if ZBTB10 influences gene expression, we used CRISPR/Cas9 knockout HEK293 and U2OS cells to...
We studied changes in a whole transcriptome during dsDNA virus infection. SOURCE: Thomas Shenk Princ...
Chrdl1, a BMP antagonist, is an astrocyte-secreted factor that promotes synapse maturation in the up...
RNA-seq analysis of the effects of etoposide treatment on transcriptomes of human pre-B, mature B, T...
Spermatogenesis is precisely cotrolled by complex gene expression programs and involves epigenetic r...
In this paper, a new circRNA was discovered by RNA sequencing, and its relationship with hepatocarci...
Second-generation CD19-targeted chimeric antigen receptors (CAR) have an antigen-binding domain fuse...
Purpose: The purpose is to systemically identify RNA expression changes along mast cell development ...
Chromatin-associated RNA-Seq of pre-B cell line B3 transduced with Ikaros (Ikaros-ERt2) or Myc (Myc-...
Transcriptome of human retinal endothelial cells (hRECs) treated with low glucose (LG), high glucose...
Following all types of neurological injury, resident macrophages are activated locally, and blood-de...
We performed transcriptome profiling for mouse dLGN (dorsolateral geniculate nucleus) tissues derive...
A major target of insulin signaling is the FoxO family of Forkhead transcription factors, which tran...
Pancreatic ductal adenocarcinoma (PDAC) is a deadly disease when diagnosed at a late stage, however ...
Transcriptome analysis of human induced hepatic progenitor cells (hiHepPCs) in various culture condi...
We performed RNA sequencing in Mouse Embryonic Fibroblasts (MEFs) of GR wild-type and GR Zn. Cells w...
Pluripotent stem cells (PSCs) have increasingly been used to model different aspects of embryogenesi...
We demonstrated that the offspring of depressed fathers display reduced resilience to stress and enh...
EMT in cancer has been associated with tumour stemness, metastasis and resistance to therapy. It has...
Combination therapy with anti PD-1 and -catenin siRNA delivered using biological nanoparticles prov...
MFN2 is a mitochondrial outer membrane protein that plays a pivotal role in mitochondrial dynamics i...
The goals of this study are to explore the function of Pten in regulating the pluripotency transitio...
Phosphorylation of the NF-B p50 subunit is known to regulate target gene expression. Here, we invest...
We report the generation of isogenic hPSC model of FXS and characterize the neurodevelopmental capac...
Autosomal dominant polycystic kidney disease (ADPKD) is a debilitating disease that is characterized...
Minichromosome maintenance (MCM) proteins facilitate replication by licensing origins and unwinding ...
Cellular diversity within tumors and reduced lineage commitment can undermine targeted therapy by in...
We used human iPSC-CMs generated from healthy individuals and performed RNA-sequencing after 7 days ...
Analysis of gene expression profile of cancer cells after T lymphocyte-cancer cell co-culture SOURCE...
We examine the effect of GPER activation on murine pancreatic ductal adenocarcinoma cell lines SOURC...
High-throughput RNA-seq analysis was performed using fresh residual CT26 tumors 3 days after incompl...
To evaluate gene expression changes in response to prolyl hydroxylase domain protein 2 and 3 (PHD2/3...
Purpose: Long non-coding RNAs (lncRNAs) have been implicated in the inflammatory response of many di...
Advances in genetics and sequencing have lead to a deluge of disease-associated and disease-causing ...
Even though genetic studies of individuals with neuromuscular diseases have uncovered the molecular ...
A hallmark of nave cell identity is the presence of two active X-chromosomes in females. However, li...
Purpose: The goals of this study are to compare NGS-derived transcriptome profiling (RNA-seq) to fin...
Cytokeratin 18(CK18), one of the major components of intermediate filaments (IF) in simple-type epit...
Although elevated KCNH2-3.1 potassium channel expression is associated with cognitive dysfunctions a...
We have mapped m6A sites and endogenous SND1 binding sites in the viral and cellular transcriptome u...
Integration of in silico and in vitro approaches to design and conduct transcriptomic drug screening...
Chemotherapy-induced hair loss (alopecia; CIA) is a highly distressing adverse effect that many canc...
Non-coding RNAs are emerging as novel regulators in adipocyte differentiation and function. Circular...
Kidneys which had been taken for transplant but later declined were perfused for up to 4 hours using...
We used the conditional chemical genetics approach known as anchor away (AA) to rapidly inactivate t...
We report that TRIM21 plays a crucial role in mediating antibody interference of adenovirus gene del...
Promoters and enhancers are key cis-regulatory elements, but how they orchestrate to generate cell-t...
Functional mutagenic screening has been used to identify key factors required for a wide range of de...
Pluripotent stem cells (PSCs) have increasingly been used to model different aspects of embryogenesi...
Human Tregs isolated from PBMCs were cultured in the absence or presence of additional NaCl (40mM) f...
Skeletal muscle insulin resistance, decreased phosphatidylinositol 3-kinase (PI3K) activation and al...
We report the differential gene expression analysis of DSS treated colon tissues obtained from WT an...
The ten-eleven translocation (Tet) proteins are well known for their role in maintaining naive pluri...
High laminar shear stress (HLSS), as observed in straight parts of arteries, assures a quiescent non...
We combined the tissue preservation and single-cell resolution of laser capture with an improved pre...
We analysed by bulk RNA seq the impact of the depletion of EZH2 on Langerhans cells SOURCE: Kaibo D...
Characterization of gene expression changes in HuH7 HCC cells upon treatment with the Jumonji KDM in...
Defining conserved molecular pathways in animal models of successful cardiac regeneration could yiel...
Goal: Determine differences in gene expression profile between microglia and macrophages isoalted fr...
We report here the transcriptome of a population enriched in enteroendocrine cells from human jejunu...
In murine glioma models, TLR2 is selectively upregulated in glioma-associated microglia. We found th...
BCR pathway inhibitors idelalisib and ibrutinib are the first small molecule targeted agents for B-c...
This scRNA-seq data is an integral part of a manuscript with the above title. Using computational me...
High macrophage infiltration in cancer is associated with reduced survival in animal models and in p...
The advent of Next Generation Sequencing has allowed transcriptomes to be profiled with unprecedente...
Renal artery stenosis (RAS) caused by narrowing of arteries is characterized by microvascular damage...
Purpose: The goals of this study are to compare transcriptome profiling (RNA-seq) in pancreatic intr...
To identify the up & down regulated genes in IL-33 transgenic mice SOURCE: Daniel,Rothschild,OBrien ...
Next generation RNA sequencing was performed to analyze changes in gene expression upon BRCA2 deplet...
Glandular epithelia including the mammary gland (MG) and the prostate are composed of basal cells (B...
RNA polymerase III (Pol III) is an essential enzyme responsible for the synthesis of several small n...
Pregnant CD-1 mice were fed control (ad libitum) and 70% total food (g) (MNR) diets from E6.5-birth....
The balance between self-renewal and differentiation of hematopoietic stem and progenitor cells (HSP...
Purpose: To investigate the impact of oncogenic Notch on the 3D genome organization of cancer cells....
Cold exposed mice were studied to investigate the genes changed in cold-induced thermogenesis. SOURC...
The colonic epithelium can undergo multiple rounds of damage and repair, often in response to excess...
We performed RNA-Seq and identified the differnetially expressed gene information among human AM-MSC...
N6-methyladenosine (m6A) modification of mRNA catalyzed by METTL3 is enriched at a subset of stop co...
Analysis of heart from myocardil specific deletion of Jarid2 by crossing Jarid2 floxed mice with aMH...
The project aims to identify differentially expressed genes in adipose progenitors that were freshly...
Theilers murine encephalomyelitis virus (TMEV) induces different diseases in the central nervous sys...
Polycomb repressive complex 2 (PRC2) is composed of EED, SUZ12, and EZH1/2, and mediates mono-, di- ...
Transcriptomics on lung-resident CD8+ T cells reveals how global gene expression patterns diverge ov...
Murine norovirus is genetically similar to human norovirus, and offers both an efficient in vitro ce...
Retinoic acid receptor beta regulates intestinal immune transcriptional programs SOURCE: Zheng Kuang...
Cardiac development relies on proper cardiomyocyte differentiation including expression and assembly...
Comparison of longitudinal transcriptomic profiles of activated human primary hepatic stellate cells...
Natural Killer (NK) cells are innate lymphoid cells (ILCs) involved in antimicrobial and antitumoral...
The goal of this study was to identify transcripts that were differentially regulated in Lgr5 hair f...
We leverage RNA sequencing to identify the transcriptional changes assocaited with several experimen...
The liver is the most common site of metastatic disease in gastrointestinal malignancies, including ...