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Talk to our team for accessPluto has a large database of published data, available to explore, conduct your own analysis, and view QC reports.
Talk to our team for accessStore large, raw sequencing data files and transform them into biologically-meaningful results in your browser. Gain critical QC information, quantify targets within and across data sets, and run best-in-class computational biology analyses specific to each assay type.
A longitudinal systems immunologic investigation of acute Zika virus infection in an individual infe...
LT-HSC and ST-HSCs were FACS sorted (>10^4cells per sample), cultured for two days in presence or ab...
CBP bromodomain inhibitor effects on mouse MDSCs sorted out of MDA-MB-231.X1.1 xenograft SOURCE: Suc...
There is growing evidence that paternal pre-conception cigarette smoke (CS) exposure is associated w...
The transcriptional regulator Rbpj is involved in T-helper (TH) subset polarization, but its functio...
Dysregulated IL-23/IL-17 responses have been linked to psoriatic arthritis and other forms of spondy...
Despite the prevalence and recognition of its detrimental impact, clinical complications of sepsis r...
We demonstrate the effects of Arg2 overexpression on murine liver gene expression by high-throughput...
Adoption of Warburg metabolism is critical for macrophage activation in response to lipopolysacchari...
The blood-brain barrier (BBB) is critical for neural function as it restricts effects of peripheral ...
To address the role of INO80/SWR-type remodeling complexes, we deleted Ep400 at defined times of mou...
PAX6 is essential for eye and forebrain development but how PAX6 instructs retinal versus neuroectod...
In this study we identified genes regulated by CASZ1b in SMS-CTR cells SOURCE: Jack Shern (john.sher...
We investigate the transcriptional changes caused by the knock-out of neuropathy linked gene CHCHD10...
Kaposi's sarcoma-associated herpesvirus (KSHV) is a human oncogenic virus, which maintains the persi...
Brown adipocytes (BAs) are a potential therapeutic cell source for the treatment of metabolic diseas...
Investigation of the ability of WT or mutant hPRDM15 to restore the transcriptional changes induced...
Ivermectin and Diethylcarbamizine (DEC) are used in the elimination programs for lymphatic filariasi...
High-throughput RNA-seq approach was used to profile transcriptional ISC niche responses in SAMP mic...
We report a new technology for the parallel bimodal analysis of RNA-seq and ATAC-seq within a single...
TET-mediated oxidation of 5-mC participates in both passive and active DNA demethylation, which exer...
We performed RNA-seq to identify the transcriptional targets of ELF4 in BE-(2)-C neuroblastoma cells...
The goals of this study is to find effect of overexpression-TRIB1 to prostate cancer cell (PC3 and D...
By transcriptionally profiling single cells from patients spanning different stages of lung adenocar...
Memory helper T cells provide long-lasting host defeMemory helper T cells provide long-lasting host ...
We used RNA-seq to profile the effect of a bacterially derived fatty on LPS-stimulated murine macrop...
In this study we identified genes regulated by CASZ1b in C2C12 cells SOURCE: Jack Shern (john.shern@...
This experiment is to examine the effect of PARP inhibitor and Myc shRNA knockdown on transcriptome ...
In metazoans, skeletal muscle evolved to contract and to produce force. Recent experimental evidence...
T helper (Th) differentiation is regulated by diverse inputs including the Vitamin A metabolite reti...
Raw files corresponding to five immunocyte populations deep sequenced using ImmGen's standard ultra-...
Previously, I have found that Mkp-1 knockout exacerbates inflammation, perturbs lipid metabolism, in...
Rationale: The atrioventricular conduction system controls ventricular activation and is delineated ...
The aim is to identify important metabolic and immune signaling pathways in memory CD8 T cells regul...
We report that microbiota dysregulation promotes LIF secretion by intestinal epithelial cells (IECs)...
Gene expression of Va7.2+CD161+CD4-CD8+MAIT cells from two subsets (CD69+CD26++ and CD69-CD26+/-). S...
Many previous attempts to derive survival models in whole blood transcriptomics data have failed. St...
Aging is a major risk factor for both genetic and sporadic neurodegenerative disorders. However, it ...
Molecular chaperones such as heat-shock proteins (HSPs) help in protein folding and complex assembly...
The study profiled the effect of Phf6 deletion on gene expression in hematopoietic stem cells (HSCs)...
We report a multi-omic study of sex differences and gene-by-sex interactions across a panel of 100 i...
Many chromatin-binding proteins and protein complexes that regulate transcription also bind RNA. One...
NFkB RelA is the potent transcriptional activator of inflammatory response genes. We stringently def...
Heterozygous loss-of-function mutations in the synaptic scaffolding gene SHANK2 are strongly associa...
Aim of the study was to elucidate YAP-regulated trophoblast-specific genes by analyzing differential...
miR-155 has recently emerged as an important promoter of antitumor immunity through its functions in...
Bulk RNA sequencing of sorted inguinal LN CD11c+ cells from healthy mice and mice subcutaneously imp...
SRSF1 is an abundant RNA-binding protein with functions in mRNA splicing, stability, translation and...
The mammalian genome is sequentially partitioned from chromosomes into looped chromatin regions term...
We explored the regulation of alternative splicing in a cell model of breast cancer resistance to do...
Maternal unbalanced nutritional habits during embryo development and perinatal stages perturb hypoth...
Systemic sclerosis (SSc) is a chronic autoimmune disease that mainly affects the connective tissue. ...
Objectives: To identify gene expression changes in acne flare-up patients, thereby exploring the mec...
Ibrutinib plus venetoclax is a highly effective combination in mantle cell lymphoma. However, strate...
Leukemia stem cells (LSCs) are regarded as the origins and key therapeutic targets of leukemia, but ...
Purpose: The objective of this study was to determine cardiac transcriptional pathways regulated in ...
miR-34a is a known tumor suppressor that targets cell proliferation and apoptosis genes. In this stu...
We implemented RNA-seq analyses of blood of 10-11M mice; These mice with the treatment of Naringenin...
Animals susceptible to chronic social defeat stress (CSDS) exhibit depression-related behaviors, and...
Investigation of the transcriptional profile of BcorE9-10KrasG12D myeloid progenitors SOURCE: Madiso...
Objective:mRNA sequencing of sorted naive CD4+ T cells from the spleens of PIK3CD GOF mice and WT li...
The goal of the current study was to characterize the cardiac transcriptional signature of the metab...
Immunoglobulin heavy chain (Igh) class switch recombination (CSR) requires B cell proliferation, ger...
As part of this study, we isolated induced pluripotent stem cells (iPSCs) from a patient with TP53-m...
SRSF2 flanked with flox was specifically depleted in the livers by Alb-Cre(HKO),and took the intact ...
The decline of hematopoietic stem cell (HSC) function upon aging contributes to the senescent immune...
We report RNA sequencing data from the Achilles, patellar, supraspinatus, and forepaw flexor tendons...
Regulatory T (Treg) cells, whose differentiation and function are controlled by transcription factor...
Vincristine, oxaliplatin, and cisplatin are commonly prescribed chemotherapeutic agents for the trea...
Purpose: Identification the biological response to fear and stress in both brain and blood is vital ...
RNAseq was used to analyse transcriptional changes occuring in WNK1-expressing or WNK1-deficient DN3...
Gamma delta T (gdT) cells with distinct properties develop in the embryonic and adult thymus and hav...
Blood-stage malaria initiates both innate and adaptive immune responses, inclusive a strong activati...
Investigation of the transcriptional consequences of Bcor loss in bone marrow transplant SOURCE: Mad...
To study the effect of SARM1 deficiency on brain transcriptome, we performed RNAsequencing of the br...
Host defense by the innate immune system requires the establishment of antimicrobial states allowing...
Microfluidic deterministic barcoding of mRNAs and proteins in tissue slides followed by high through...
The study investigates CTCF/cohesin binding and chromatin looping by ChIP-seq and Micro-C. By ChIP-s...
We compared the global transcriptomes of wild type and SphK2 null fibroblasts by RNA-seq as a first ...
Zbtb11 is an uncharacterised transcription factor that is conserved in vertebrates. Mutations in its...
Coordinated changes of DNA (de)methylation, nucleosome positioning and chromatin binding of the arch...
Organisms have adapted to the changing environmental conditions within the 24h cycle of the day by t...
Genome-wide association studies (GWAS) have identified 100s of loci associated with coronary artery ...
Six2 may play a role in mediating stemness characteristics during tumor progression as during develo...
By co-culturing murine keratinocytes with splenic T cells we show here that T cells affect the synth...
Expression of co-inhibitory receptors, such as CTLA-4 and PD-1, on effector T cells is a key mechani...
Atherosclerosis is a lipid-driven chronic inflammatory disorder of the arteries in which macrophages...
Aging is a major risk factor for many neurological pathologies, including Alzheimers disease (AD). H...
Activation of transcription enhancers, especially super enhancers, is one of the important epigeneti...
Examination of ribosome-bound mRNA at five timepoints (in duplicates) during oocyte meiosis (prophas...
ILC3s from the spleen (SP) and small intestine (SI) have been shown to be phenotypically and functio...
Increased energy requirement and metabolic reprograming is a hallmark of cancer cells. We found that...
We conducted genome wide transcription profiling by RNA-seq in a mouse hippocampal cell line (HT22),...
Summary: Cell fate transitions are accompanied by global transcriptional, epigenetic and topological...
To understand the EZHIP-mediated transcriptional profile in mouse embryonic fibroblasts SOURCE: Pete...
Studies in mice have indicated that TPL2 kinase plays important roles in immune responses to pathoge...
Mitochondria fulfill vital metabolic functions and act as crucial cellular signaling hubs integratin...
Myotonic dystrophy type 1 (DM1) is a multisystemic genetic disorder caused by a CTG trinucleotide r...
We report the application of RNA sequencing technology for high-throughput profiling of gene express...
Excessive consumption of beverages sweetened with high-fructose corn syrup (HFCS) is associated with...