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Sequencing-based assays page 95
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GSE137116: Developmental trajectory of pre-hematopoietic stem cell formation from endothelium (scRNA-seq data set)
To examine the cell and molecular transitions between endothelial (E), hemogenic endothelial (HE), a...
GSE142163: Oocyte RNA-seq data of WT, Tet1-/- and Tet2-/-; RNA seq of PGC at E13.5
Differential functions of Tet 1 and Tet2 in oocyte development and quality control link to reproduct...
GSE142636: Transcriptome of Human Primary Corneal Endothelial Cells with SLC4A11 deficiency
Mutations in the solute-linked carrier family 4 member 11 (SLC4A11) gene are associated with several...
GSE136558: Nickel induced transcriptional changes persist post exposure through epigenetic reprograming (RNA-seq dataset)
Nickel is an occupational and environmental toxicant associated with a number of diseases. Our earli...
GSE128571: E11.5 Hand1 myocardial knockout RNA-Seq
Aims: To examine the role of the basic Helix-loop-Helix (bHLH) transcription factor HAND1 in embryon...
GSE133978: RNA-seq of cold stimulated inguinal fat of wild type and Rarres2-/- mice
Although various stimuli and mediators have been identified to promote thermogenic beige fat develop...
GSE136569: circNFIB suppresses lymphatic metastasis of pancreatic cancer
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignany and currently the fourth...
GSE141972: TGF-activated kinase 1-dependent microglial and macrophage responses aggravate long-term outcomes after ischemic stroke
Microglia/macrophages (Mi/M) can profoundly influence stroke outcomes by acquiring functionally domi...
GSE142166: Transcriptional response of intestinal epithelial cells to type I and III IFN
RNAseq of intestinal epithelial cell (IEC) organoids and treated with PBS, interferon beta (IFNB), o...
GSE130298: Hematopoietic stem cells in perisinusoidal niches are protected from ageing [aged, GFP-label retaining HSCs]
With ageing, intrinsic hematopoietic stem cell (HSC) activity decreases, resulting in impaired tissu...
GSE137584: Genome-wide CRISPR interference screen identifies long non-coding RNA loci required for differentiation and pluripotency
Systematic identification of factors that regulate human embryonic stem cell (hESC) differentiation ...
GSE142019: Effect of Ythdf2 in haematopoiesis [RNA-seq]
The mRNA m6A reader YTHDF2 is overexpressed in human acute myeloid leukaemias. To understand the ro...
GSE132265: Inactivation of Sox9 in fibroblasts reduces cardiac fibrosis and inflammation in mice after myocardial infarction
Fibrotic scarring drives the progression of heart failure after myocardial infarction (MI). Therefor...
GSE143365: Transcriptional profile of T, ITNK and NK cells
To further characterize the global gene expression profiles of ITNKs, we conducted RNA-sequencing an...
GSE145894: cirRNA-seq of the fourth passage xenografts treated with 5-Fu and PBS
In this study, we established a successive xenograft model to enrich Epstein-Barr virus-associated g...
GSE142000: The significance of interleukin 2 receptor subunit gamma in the progression of human gastric cancer
IL2RG is overexpressed in advanced GC and is associated with poor survival. IL2RG may serve as a bio...
GSE126785: Transcriptomic analysis of iPSC and ESC challenged with atmospheric or physiological oxygen
Modulation of metabolism by 5% (physiological) oxygen during reprogramming has been shown to improve...
GSE142169: MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression
Misregulation of long non-coding RNA genes has been linked to a wide variety of cancer types. Here w...
GSE136597: Transcriptome analysis of MUTU I and MUTU III cells
RNAseq was used to identify host and viral transcriptome changes in MUTU I and MUTU III cells. SOURC...
GSE141124: Loss of Lamin A/C in myeloid cells promotes lung metastasis through Gfi-1 and C/EBPe-mediated granulocytic differentiation
The immune suppressive tumor microenvironment contributes to metastatic spread. In particular, tumor...
GSE145984: Total RNA-Seq of KHSRP knockdown (KD) and control samples in HepG2 and K562
We profile the expression of circular RNAs (circRNAs) upon KHSRP KD in HepG2 and K562 cells SOURCE: ...
GSE142022: RNA-seq profiling of astrocytes after microglial ablation
Astrocytes become activated in a mouse model of microglial ablation. We isolated astrocytes from hip...
GSE143403: The Xenobiotic Transporter Mdr1 Enforces T Cell Homeostasis in the Presence of Intestinal Bile Acids [shMdr1 RNA-seq in vivo]
CD4+ T cells are tightly regulated by microbiota in the intestine, but whether intestinal T cells in...
GSE155654: Effects of TNFR1 deletion in mice in early life
Athough anti-TNF therapies can be used to treat colitis associated with inflammatory bowel disease, ...
GSE136580: Rare pulmonary neuroendocrine cells are stem cells regulated by Rb, p53, and Notch
Pulmonary neuroendocrine (NE) cells are neurosensory cells sparsely distributed throughout the bronc...
GSE142017: Dysregulation of MITF in the context of defective MC1R and RB1/p16/CDK4 leads to melanocyte transformation [RNA-Seq]
RNAseq Expression analysis of immortalized melanocytes Hermes 3c (3C) and Hermes 4c (4C) cell lines ...
GSE143277: Translation is required for miRNA-dependent decay of endogenous transcripts.
Posttranscriptional repression by microRNA (miRNA) occurs through transcript destabilization or tran...
GSE131776: Single cell analysis of smooth muscle cell phenotypic modulation in vivo during disease in mice and humans [mouse scRNA-seq]
In response to various stimuli, vascular smooth muscle cells (SMCs) can de-differentiate, proliferat...
GSE137170: Transcriptome reprogramming via Tob2-promoted global mRNA turnover
We found that multilayered phosphorylation of human Tob2 modulates its PABP-binding ability to chang...
GSE129137: RNA-seq using RNA from KDM4 WT and Knockout haematopoietic stem cells
The KDM4/JMJD2 are H3K9- and H3K36- specific demethylases, which are considered promising therapeuti...
GSE136536: Ketogenic diet activates protective T cell responses against influenza virus infection
Influenza A virus (IAV) infection-associated morbidity and mortality are a key global healthcare con...
GSE152118: Gene expression analysis of E2A forced homodimer overexpression in mouse embryonic stem cells.
We set out to investigate whether overexpression of the bHLH transcription factor, E2A, is sufficien...
GSE137365: Evaluation of the physiological property of D-allulose on obesity and its comorbidities in diet-induced obese mice based on mRNA-seq analysis
ackground/Objectives: The aim of the current study was to elucidate the effects of long-term supplem...
GSE128781: A single-cell atlas of mouse brain macrophages reveals unique transcriptional identities shaped by ontogeny and tissue environment. [bulk RNA-Seq]
While the roles of parenchymal microglia in brain homeostasis and disease are fairly clear, other br...
GSE137215: RNA-seq of the lens transition zone in control vs Pea3-depleted mouse embryonic tissue
The goal of the study is to find the transcriptional targets downstream of Pea3-mediated signaling d...
GSE143371: Transcriptome analysis of differentiated human embryonic stem cells (hESCs) upon CRISPR/Cas9-mediated mutagenesis of lineage-specific and common essential genes
Pluripotentstemcells can differentiate into all embryonic germ layers, a process that is orchestrate...
GSE137022: RNA-seq from adipose and liver tissue in Fam13a knockout and wildtype mice on different diets
We performed RNA-sequencing of liver, visceral and subcutaneous adipose tissues from Fam13a KO/WT mi...
GSE150811: The AP-1/JNK pathway is regulated by CD73 and gets dysregulated in aged hosts leading to defect in anti-pneumococcal function of neutrophils
We used high through put RNA-sequencing to identify changes in the PMN transcriptome induced by S. p...
GSE137203: mRNA expression data of Tumor budding cells and Tumor center cells
The gene expression in Tumor budding cells was substantially different from that in the cells of tu...
GSE141103: Amplification of Oocytes through Parthenogenesis
We asked whether oocyte number could be amplified through parthenogenesis of mouse oocytes, without ...
GSE146012: Gene expression of primary tumor and lung metastases in 4T1 mouse mammry tumor model
We sorted GFP-labeled 4T1 cells from primary tumor and lung metastases and performed mRNA sequencing...
GSE142705: Snai2 maintains bone marrow niche cells by repressing osteopontin expression
Bone marrow (BM) mesenchymal stem and progenitor cells (MSPCs) are a critical constituent of the hem...
GSE137025: Bulk RNA-seq on SEMA7A high and negative Idiopathic pulmonary fibrosis (IPF) lung fibroblasts
To check the gene signatures of SEMA7A high and SEMA7Anegative IPF lung fibroblasts and the similari...
GSE143388: Loss Of Neural Stem Cell O-Glcnacylation Regulates An Age-Related Fate Switch In The Mature Hippocampus
To gain mechanistic insight into the role of O-GlcNAc in adult hippocampal neural stem cells (NSCs),...
GSE137030: The role of the core PRC1 members Ring1 and Rnf2 in expression regulation during oocyte growth
Comparative expression analysis between germinal vesicle (GV) stage mouse oocytes of Ring1-deficient...
GSE137211: The lncRNA NEAT1_1 is seemingly dispensable for normal tissue homeostasis and cancer cell growth
NEAT1 is one of the most studied lncRNAs, in part because its silencing in mice causes defects in ma...
GSE142644: Whole transcriptomes analyses of gastric tumor tissues derived from Mst4F/F UBCcre (Mst4 KO) mice and wildtype (WT) mice
To explore whether Mst4 limits YAP signaling and suppresses GC development in vivo, RNA sequencing w...
GSE131751: RNAseq of renal dendritic cells from adult Clec9a-Cre Rosa-YFP mice
We use bulk RNA sequencing of sorted cells to characterize the gene expression profiles of renal den...
GSE129177: DNMT1 is required for proximal-distal patterning of the lung endoderm and restraining alveolar type 2 cell fate
Lung endoderm development occurs through a series of finely coordinated transcriptional processes th...
GSE135350: The XPO1 inhibitor KPT-8602 synergizes with dexamethasone for the inhibition of acute lymphoblastic leukemia
Acute lymphoblastic leukemia (ALL) is the most common pediatric cancer. Survival of ALL patients has...
GSE136604: RNA-seq comparative analysis of HOTAIRM1 knockdown in Caki-1 cells
RNA-seq comparative analysis of HOTAIRM1 knockdown in Caki-1 cells SOURCE: Michael Hamilton (mihamil...
GSE129028: Glycosylation-dependent modulation of the IL-2 signaling axis determines Th17 differentiation and IL-10 production
Metabolism plays an essential role in shaping Th cell responses including the production of pro-infl...
GSE150838: Humanized C3 Mouse: A Novel Accelerated Model of C3 Glomerulopathy
We developed a novel, rapidly-progressing, severe murine model of C3G by replacing the mouseC3 genew...
GSE142677: Ago HITS-CLIP in adipose tissue reveals mir-29 as a post-transcriptional regulatory of leptin
wildtype mouse adipose tissue was dissected and subjected to Ago-CLIP sequencing to identify Ago:RNA...
GSE135296: Hippo Pathway Deletion in Adult Resting Cardiac Fibroblasts Initiates a Cell State Transition with Spontaneous and Self-Sustaining Fibrosis
Cardiac fibroblasts (CFs) respond to injury by transitioning through multiple cell states, including...
GSE143946: Blood Serum Stimulates p38-Mediated Proliferation and Changes in Global Gene Expression of Adult Human Cardiac Stem Cells
Global transcriptome analysis of blood serum-treated adult human cardiac stem cells shows p38-MAPK m...
GSE145922: IL-23 promotes a coordinated B-cell germinal center program for class-switch recombination to IgG2b in BXD2 mice
IL-23 promotes autoimmune disease including Th17 CD4 T-cell development and autoantibody (autoAb) pr...
GSE142667: Urinary Cell Transcriptomics and Acute Rejection in Human Kidney Allografts
RNA-sequencing (RNA-Seq) is a precise tool to analyze global transcriptional changes, develop biomar...
GSE128838: Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug [mouse P1]
Williams syndrome (WS), caused by a heterozygous microdeletion in 7q11.23, is a neurodevelopmental d...
GSE128710: RNA-seq analysis of freshly isolated germinal center B cells
Purpose: The goal of this study is to complare the transcitpional profiles of freshly isolated, sple...
GSE141190: EXOSC10 sculpts the transcriptome during oocyte growth-to-maturation transition
Growing mammalian oocytes accumulate substantial amounts of RNA, most of which are degraded during t...
GSE126885: Fatty acid transporter 2 regulates lipid metabolism and suppressive function of neutrophils in cancer
Polymorphonuclear myeloid derived suppressor cells (PMN-MDSC) are pathologically activated neutrophi...
GSE136574: Genome-wide RNA sequencing on myeloid derived suppressor cells from mice treated with lymphodepleting chemotherapy
Myeloid derived suppressor cells (MDSCs) were sorted from B16 tumor-bearing mice that were untreated...
GSE140182: Single cell RNA sequencing of advanced gastric cancer
To define the cellular characteristics of malignant ascites of advanced gastric cancer patients and ...
GSE128675: Rhythmic chromatin interactions with lamin B1 in liver reflect stochasticity in variable lamina-associated domains during the circadian cycle
Purpose: Many mammalian genes exhibit circadian expression patterns concordant with periodic binding...
GSE128719: Transcriptome sequencing of purified dermal adipocytes and inguinal adipocytes
Purpose: The goals of this study are to compare the transcription difference between purified dermal...
GSE129347: Anti-inflammatory effects of HDL in macrophages predominate over pro-inflammatory effects in atherosclerotic plaques
HDL infusion reduces atherosclerosis in animal models and is being evaluated as a treatment in human...
GSE135382: Dissecting cellular crosstalk by sequencing physically interacting cells
Crosstalk between neighboring cells underlines many biological processes, such as cell activation, d...
GSE137205: RNA-Seq of livers of male C57/BL6N and Scly KO mice on diets containing 0.08 ppm (low) and 0.25 ppm (adequate) sodium selenite
We report the application of RNA sequencing technology for transcriptomic profiling in murine livers...
GSE136596: Transcriptome analysis to UHRF1 depletion in RaeL cells
RNAseq was used to identify host and viral transcriptome changes in UHRF1 knock-out RaeL cells. UHR...
GSE131798: Transcriptional analysis of tendons from mice with a tenocyte-specific deletion of IGF1R
We report RNA sequencing data from the plantaris tendons of adult male mice in the C57Bl/6 backgroun...
GSE144503: -Catenin and FGFR2 Regulate Postnatal Rosette-Based Adrenocortical Morphogenesis
We show that -catenin stabilization leads to increased FGFR2, which is required for rosette formatio...
GSE142750: Single cell transcriptome sequencing of gastric cancer cell lines
We report the integrative analysis of single cell genome and transcriptome characteristics of gastri...
GSE143340: Canonical Wnt pathway controls mESCs self-renewal through inhibition of spontaneous differentiation via -catenin/TCF/LEF functions
The Wnt/-catenin signalling pathway is a key regulator of embryonic stem cell self-renewal and diffe...
GSE137208: Epigenetic and metabolic remodeling during the acquisition of extended pluripotency
Totipotent cells with bidirectional chimeric ability attracts more attention from developmental biol...
GSE136591: Akap11 is a positive regulator of osteogenesis in mouse osteoblastic cell line MC3T3-E1
Purpose: This is a post-GWAS functional study that aims to determine the effect of Akap11 knockout i...
GSE137152: Sustained fetal hematopoiesis causes juvenile death from leukemia: evidence from a dual-age-specific mouse model
After decades of efforts to simulate juvenile myelomonocytic leukemia (JMML) in mice, with its assoc...
GSE138007: Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation [RNA_LinNegBM]
Transcriptional regulators, including the cohesin complex member STAG2, are recurrently mutated in c...
GSE128839: Neuronal deletion of Gtf2i, associated with Williams syndrome, causes behavioural and myelin alterations rescuable by a remyelinating drug [mouse P30]
Williams syndrome (WS), caused by a heterozygous microdeletion in 7q11.23, is a neurodevelopmental d...
GSE152114: Transcriptome analysis of Human Cytomegalovirus (HCMV) infected nasal turbinate tissues
We report the application of RNA sequencing for transcriptome analysis of HCMV infected Human nasal ...
GSE130256: Innate Lymphoid Cells-Containing Fraction of Murine Lamina Propria Cells Produces Interleukin-17 upon Incubation with Giardia lamblia
Innate lymphoid cells (ILCs) are key players during an immune response at the mucosal surfaces, such...
GSE138045: Genome-wide transcriptome alternation by DNA methylation inhibitor 5'-Aza in primary leiomyoma cells
Uterine leiomyomas (LM) affect up to 80% of all reproductive-age women. LM growth requires progester...
GSE142657: Cocaine-mediated circadian reprogramming in the striatum through a dopamine D2 receptor-PPARg circuit
Cocaine-dependent genome-wide effects were analyzed, total RNAs were extracted from ventral striatum...
GSE137026: Single cell RNA-seq revealed critical genetic programs of invasive fibroblasts for pulmonary fibrosis
We performed a single cell RNA-seq survey of 14,704 invasive fibroblasts and 16,104 non-invasive fib...
GSE136639: Genome-wide RNA sequencing on myeloid derived suppressor cells from mice treated with lymphodepleting chemotherapy reveals distinct IL-6 driven regulatory patterns
Myeloid derived suppressor cells (MDSCs) were sorted from B16 tumor-bearing mice, WT and IL-6KO, tha...
GSE135865: Protease-activated receptor-2 promotes osteogenesis in skeletal mesenchymal stem cells at the expense of adipogenesis
Osteoblast-like cells isolated from the calvariae of wildtyope and protease-activated receptor-2 nul...
GSE141782: Whole population RNASeq of pancreatic islet macrophages during autoimmune diabetes progression
Whole population RNASeq of pancreatic islet macrophages during autoimmune diabetes progression. SOUR...
GSE143391: Impact of Microbiome on Hepatic Drug Processing Genes in Mice during Pregnancy
While microbiome and pregnancy are known to alter drug disposition, the interplay of the two physiol...
GSE144186: Transcriptional control of thermogenesis by early B cell proteins [RNA-seq]
Early B Cell Factor 2 (EBF2) is required for brown adipose tissue basal thermogenic gene expression;...
GSE136619: Whole exome and transcriptome sequencing of murine tumor models
These data were used for prediction of neoantigens and minor histocompatibility mismatch antigens, w...
GSE137039: Comparison of tumor-associated YAP1 fusions identifies a recurrent set of functions critical for oncogenesis [mouse RNA-seq]
Several different YAP1 gene fusions have been identified in various human cancers. We performed RNA ...
GSE138077: Genome-wide transcriptomic analysis in pediatric glioblastomas cell lines by RNA-seq.
We identified that RACK7 recognizes the histone H3.3G34R mutaion in vitro and in vivo. In order to e...
GSE146027: Transcriptome of murine gastric cancer treated with anti-IL-17, PD-1 or CTLA-4 antibodies.
YTN2 and YTN16 cells are chemically induced gastric cancer cell lines. YTN2 is spontaneously regress...
GSE138470: Loss of transcription factor EB action remodel lipid metabolism and cell death pathways in the cardiomyocyte
Loss of TFEB action, impaired lysosomal autophagy and increased proteotoxicity are observed in numer...
GSE136634: Clinical and biological implications of target occupancy in chronic lymphocytic leukemia treated with acalabrutinib
Inhibition of the B-cell receptor pathway, and specifically of Bruton tyrosine kinase (BTK), is a le...
GSE142678: Adult Born Hippocampal Neurons Mount Unique Translational Changes in Response to Voluntary Running
We report the genome-wide gene expression in adult born hippocampal neurons (at three different stag...
GSE134005: Transcriptome Clarifies Mechanisms of Lesion Genesis Versus Progression in Models of Ccm3 Cerebral Cavernous Malformations [RNA-seq]
Cerebral cavernous malformations (CCMs) are dilated capillaries causing epilepsy and stroke.; Inheri...
GSE136610: Fluidigm single-cell RNA-seq analysis for gene signatures associated with T-cell persistence
A patient (4095) with metastatic colorectal cancer was treated with polyclonal tumor infiltrating ly...
GSE137028: Transcriptomic profiling of microglia and astrocytes throughout aging
Purpose:The goal of this study are to understand the role of miceoglia and astrocyte in both physiol...
GSE139412: Continuous and discrete neuron types of the adult murine striatum
The mammalian striatum is involved in many complex behaviors and yet is largely composed of a single...